Skip to main content

Veterinary RNA viruses

Section Editor: Siba Samal, University of Maryland, USA

The Veterinary RNA viruses section of Virology Journal covers research on RNA viruses of non-human animals, including food, companion, and wild animal species. Both reviews and original research papers on viral structure, function and genetics will be considered as well as articles focusing on viral pathogenesis, virus-host interactions, vaccines, and antiviral therapeutics.

Page 1 of 3

  1. Canine distemper virus (CDV) infection of ferrets, dogs, and giant pandas causes an acute systemic disease involving multiple organ systems, including the respiratory tract, lymphoid system, and central nervou...

    Authors: Jingjian Dong, Yan Chen, Lili Shi, Bing Shen, Xianliang Sun, Kaiyi Ruan, Xianzhu Xia, Hao Feng and Na Feng

    Citation: Virology Journal 2021 18:229

    Content type: Research

    Published on:

  2. Interleukin (IL)-38, a novel member of the IL-1 family, has been reported to be involved in several diseases associated with viral infection. However, the expression and functional role of IL-38 in acute viral...

    Authors: Yimin Xue, Mingguang Chen, Qian Chen, Tingfeng Huang, Qiaolian Fan, Fenghui Lin, Jun Ke and Feng Chen

    Citation: Virology Journal 2021 18:220

    Content type: Research

    Published on:

  3. Porcine vesicular disease is caused by the Seneca Valley virus (SVV), it is a novel Picornaviridae, which is prevalent in several countries. However, the pathogenicity of SVV on 5–6 week old pigs and the transmis...

    Authors: Jinyong Zhang, Chenghui Li, Yuan Meng, Yubiao Xie, Ning Shi, He Zhang, Chengdong Yu, Fulong Nan, Changzhan Xie, Zhuo Ha, Jicheng Han, Zhuoxin Li, Qiuxuan Li, Peng Wang, Xu Gao, Ningyi Jin…

    Citation: Virology Journal 2021 18:209

    Content type: Research

    Published on:

  4. As genetic analysis becomes less expensive, more comprehensive diagnostics such as whole genome sequencing (WGS) will become available to the veterinary practitioner. The WGS elucidates more about porcine repr...

    Authors: Jessica Risser, Matthew Ackerman, Robert Evelsizer, Stephen Wu, Byungjoon Kwon and James Mark Hammer

    Citation: Virology Journal 2021 18:206

    Content type: Review

    Published on:

  5. Chikungunya fever, caused by the Chikungunya virus (CHIKV), has become a major global health concern, causing unexpected large outbreaks in Africa, Asia, Europe, and the Americas. CHIKV is not indigenous to Ch...

    Authors: Shaofu Qiu, Jinpeng Guo, Peihan Li, Peng Li, Xinying Du, Rongzhang Hao, Chaojie Yang, Qi Wang, Hongbo Liu, Haoran Zhang, Sai Tian, Hua Shi, Liang Wen, Daizhi An, Xiaocui Yang, Xiaoyuan An…

    Citation: Virology Journal 2021 18:203

    Content type: Short report

    Published on:

  6. Despite the fact that the chikungunya viral infection is a neglected disease, complications such as hemorrhagic fever, arthritis, and lymphopenia remain a health concern. The aim of this study was to determine...

    Authors: Abdulrahim R. Hakami, Abdullah A. Alshamrani, Mohamad Alqahtani, Yasser Alraey, Razan A. Alhefzi, Sultan Alasmari, Mohamed Makkawi, Gasim Dobie, Mushtaq Mir, Mohamed Alshahrani, Ayed Dera, Mohammed Alfaifi, Mesfer Al Shahrani, Ahmad Matari and Ali Essa Asiry

    Citation: Virology Journal 2021 18:190

    Content type: Research

    Published on:

  7. Canine distemper caused by canine distemper virus that belongs to the Morbillivirus genus of the Paramyxoviridae family is still a global epidemic significant infectious disease, especially in pet dogs in China a...

    Authors: Yaoqian Pan, Shuai Wang, Peng Li, Feng Yue, Yanfang Zhang, Bo Pan and Xingyou Liu

    Citation: Virology Journal 2021 18:165

    Content type: Research

    Published on:

  8. Bovine viral diarrhea (BVD) which is caused by Bovine viral diarrhea virus (BVDV), is an acute, contagious disease. In spite of the use of vaccines and elimination projects, BVDV still causes severe economic l...

    Authors: Yaxin Li, Tao Guo, Xiaokui Wang, Wei Ni, Ruirui Hu, Yuying Cui, Taotao Mi and Shengwei Hu

    Citation: Virology Journal 2021 18:119

    Content type: Research

    Published on:

  9. Newcastle disease is a devastating disease in poultry caused by virulent Newcastle disease virus (NDV), a paramyxovirus endemic in many regions of the world despite intensive vaccination. Phylogenetic analyses...

    Authors: Ibrahim Moharam, Olayinka Asala, Sven Reiche, Hafez Hafez, Martin Beer, Timm Harder and Christian Grund

    Citation: Virology Journal 2021 18:86

    Content type: Research

    Published on:

  10. Encephalomyocarditis virus, member of Cardiovirus genus within Picornaviridae family, is an important pathogen that infects different domestic and wild animals. However, the molecular mechanism of its entry remai...

    Authors: Qiongyi Li, Yang Liu, Shujuan Xu, Kexue Zhao, Ying Ling, Rongxiu Liu, Amjad Ali and Jialin Bai

    Citation: Virology Journal 2021 18:63

    Content type: Research

    Published on:

  11. Classical swine fever (CSF) caused by the classical swine fever virus (CSFV) is a highly contagious swine disease resulting in large economical losses worldwide. The viral envelope glycoprotein E2 and Erns are ma...

    Authors: Qiang Wei, Yilin Bai, Yapeng Song, Yunchao Liu, Wei Yu, Yaning Sun, Li Wang, Ruiguang Deng, Guangxu Xing and Gaiping Zhang

    Citation: Virology Journal 2021 18:44

    Content type: Short report

    Published on:

  12. Japanese encephalitis virus is a mosquito-borne neurotropic flavivirus that causes acute viral encephalitis in humans. Pigs are crucial amplifier host of JEV. Recently, increasing evidence has shown that long ...

    Authors: Xiaolong Zhou, Qiongyu Yuan, Chen Zhang, Zhenglie Dai, Chengtao Du, Han Wang, Xiangchen Li, Songbai Yang and Ayong Zhao

    Citation: Virology Journal 2021 18:29

    Content type: Research

    Published on:

  13. The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is a major antigen that can induce protective antibodies in poultry. However, its antigenic epitopes have not been fully elucidated...

    Authors: Zhongyuan Jin, Qiaolin Wei, Youkun Bi, Yongshan Li, Na Huo, Sujing Mou, Wenbin Wang, Haijin Liu, Zengqi Yang, Hongjun Chen and Sa Xiao

    Citation: Virology Journal 2021 18:8

    Content type: Research

    Published on:

  14. Street rabies virus (RABV) usually infects hosts at peripheral sites and migrates from motor or sensory nerves to the central nervous system. Several studies have found that inflammation is mild in a mouse mod...

    Authors: Shu Qing Liu, Yuan Xie, Xin Gao, Qian Wang and Wu Yang Zhu

    Citation: Virology Journal 2020 17:157

    Content type: Research

    Published on:

  15. Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically devastating diseases affecting the pork industry globally. PRRS is caused by PRRS virus (PRRSV). Currently there are no effe...

    Authors: Chang Huang, Denzil Bernard, Jiaqi Zhu, Radha Charan Dash, Alexander Chu, Alec Knupp, Anna Hakey, M. Kyle Hadden, Antonio Garmendia and Young Tang

    Citation: Virology Journal 2020 17:116

    Content type: Research

    Published on:

  16. Infectious hematopoietic necrosis virus (IHNV) and viral hemorrhagic septicemia virus (VHSV) are highly contagious, pathogenic Novirhabdoviruses affecting fish and are thusly notifiable diseases with the World...

    Authors: Bartolomeo Gorgoglione, Jeffery L. Ringiesn, Loc H. Pham, Brian S. Shepherd and Douglas W. Leaman

    Citation: Virology Journal 2020 17:110

    Content type: Research

    Published on:

  17. More than 3 years since the last Zika virus (ZIKV) outbreak in Brazil, researchers are still deciphering the molecular mechanisms of neurovirulence and vertical transmission, as well as the best way to control...

    Authors: Paula A. Faria Waziry, Aarti Raja, Chloe Salmon, Nathalia Aldana, Sruthi Damodar, Andre Rinaldi Fukushima and Bindu S. Mayi

    Citation: Virology Journal 2020 17:93

    Content type: Research

    Published on:

  18. Bovine viral diarrhea virus (BVDV) is a cause of substantial economic loss to the cattle industry worldwide, and there are currently no effective treatment or preventive measures. Bovine enterovirus (BEV) has ...

    Authors: Xiao Ren, Shan Zhang, Xintao Gao, Xiaoyu Guo, Ting Xin, Hongfei Zhu, Hong Jia and Shaohua Hou

    Citation: Virology Journal 2020 17:88

    Content type: Research

    Published on:

  19. A prevalent PEDV strain, designated FJLY06, was isolated from Fujian, China. The four of structural genes sequences of PEDV obtained were analyzed to determine their phylogenetic relationships and homology res...

    Authors: Bo Dong, Ailing Dai, Xiaohua Li and Xiaoyan Yang

    Citation: Virology Journal 2020 17:79

    Content type: Short report

    Published on:

  20. Bovine viral diarrhea virus (BVDV) belongs to the Flaviviridae family and the pestivius virus group. BVDV is responsible for significant economic loss in cattle industry worldwide because of reducing reproductive...

    Authors: Xiaowei Gong, Qiwei Chen and Fuying Zheng

    Citation: Virology Journal 2020 17:59

    Content type: Research

    Published on:

  21. Cypoviruses (CPVs) are RNA viruses with segmented double-stranded genome and major pathogens of various insects, including economic insects like silkworms and pest insects for agricultural crops and forests. G...

    Authors: Zhendong Zhang, Ning Li, Chengxiang Hou, Kun Gao, Xudong Tang and Xijie Guo

    Citation: Virology Journal 2020 17:48

    Content type: Short report

    Published on:

  22. Porcine epidemic diarrhea virus (PEDV) infection causes an acute enteric tract infectious disease characterized by vomiting, anorexia, dehydration, weight loss and high mortality in neonatal piglets. During PE...

    Authors: Ning Kong, Qiong Meng, Yajuan Jiao, Yongguang Wu, Yewen Zuo, Hua Wang, Dage Sun, Sujie Dong, Huanjie Zhai, Wu Tong, Hao Zheng, Hai Yu, Guangzhi Tong, Yongjie Xu and Tongling Shan

    Citation: Virology Journal 2020 17:46

    Content type: Research

    Published on:

  23. Pneumonia and stomatitis represent severe and often fatal diseases in different captive snakes. Apart from bacterial infections, paramyxo-, adeno-, reo- and arenaviruses cause these diseases. In 2014, new viru...

    Authors: Silvia Blahak, Maria Jenckel, Dirk Höper, Martin Beer, Bernd Hoffmann and Kore Schlottau

    Citation: Virology Journal 2020 17:6

    Content type: Research

    Published on:

  24. The foot-and-mouth disease (FMD) virus is classified into seven serotypes, of which the South African types have South African Territories (SAT)1, SAT2, and SAT3 that are prevalent in Africa. Especially SAT2 h...

    Authors: Hye-Eun Jo, Su-Hwa You, Joo-Hyung Choi, Mi-Kyeong Ko, Sung Ho Shin, Jisoo Song, Hyundong Jo, Min Ja Lee, Su-Mi Kim, Byounghan Kim and Jong-Hyeon Park

    Citation: Virology Journal 2019 16:156

    Content type: Research

    Published on:

  25. Bluetongue virus (BTV), an emerging insect vector mediated pathogen affecting both wild ruminants and livestock, has a genome consisting of 10 linear double-stranded RNA genome segments. BTV has a severe econo...

    Authors: Qingyuan Xu, Jinying Ge, Maolin Li, Encheng Sun, Yawei Zhou, Yunze Guo, Donglai Wu and Zhigao Bu

    Citation: Virology Journal 2019 16:151

    Content type: Methodology

    Published on:

  26. Capsid (C) protein plays an important role in the replication of classical swine fever virus (CSFV). The ubiquitin proteasome system (UPS) involves in replication of many viruses via modulation of viral protei...

    Authors: Yuming Chen, Erpeng Zhu, Shuangqi Fan, Hongxing Ding, Shengming Ma, Mengjiao Zhu, Shaofeng Deng, Jinding Chen and Mingqiu Zhao

    Citation: Virology Journal 2019 16:127

    Content type: Research

    Published on:

  27. Reverse genetics systems enable the manipulation of viral genomes and therefore serve as robust reverse genetic tools to study RNA viruses. A DNA-launched rescue system initiates the transcription of viral gen...

    Authors: Ruihua Zhang, Jingjing Lan, Haie Li, Junhao Chen, Yupeng Yang, Shaoli Lin, Zhijing Xie and Shijin Jiang

    Citation: Virology Journal 2019 16:112

    Content type: Research

    Published on:

  28. Transmissible gastroenteritis virus (TGEV), a member of the family Coronaviridae, causes lethal watery diarrhea in piglets. Previous studies have revealed that the coronaviruses develop various strategies to evad...

    Authors: Yanan Wang, Aoying Sun, Yu Sun, Sijia Zhang, Tian Xia, Tiantian Guo, Zhenye Hao, Li Sun, Yanping Jiang, Xinyuan Qiao, Wen Cui, Lijie Tang, Yigang Xu, Yijing Li and Li Wang

    Citation: Virology Journal 2019 16:97

    Content type: Research

    Published on:

  29. Lates calcarifer, known as seabass in Asia and barramundi in Australia, is a widely farmed species internationally and in Southeast Asia and any disease outbreak will have a great economic impact on the aquacultu...

    Authors: Jing Chen, Xinyu Toh, Jasmine Ong, Yahui Wang, Xuan-Hui Teo, Bernett Lee, Pui-San Wong, Denyse Khor, Shin-Min Chong, Diana Chee, Alvin Wee, Yifan Wang, Mee-Keun Ng, Boon-Huan Tan and Taoqi Huangfu

    Citation: Virology Journal 2019 16:71

    Content type: Research

    Published on:

  30. The picornaviral 3C protease mediates viral polyprotein maturation and multiple cleavages of host proteins to modulate viral translation and transcription. The 3C protease has been regarded as a valid target d...

    Authors: Di Sun, Mingshu Wang, Xingjian Wen, Sai Mao, Anchun Cheng, Renyong Jia, Qiao Yang, Ying Wu, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Xiaoyue Chen, Yunya Liu, Yanling Yu…

    Citation: Virology Journal 2019 16:54

    Content type: Research

    Published on:

  31. Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and has a negative impact on equine breeding enterprises worldwide. Among ERVA strains infecting foals, the genotypes G3P[12] and G1...

    Authors: Mariano Carossino, Maria E. Barrandeguy, Erdal Erol, Yanqiu Li and Udeni B. R. Balasuriya

    Citation: Virology Journal 2019 16:49

    Content type: Research

    Published on:

  32. Piscine orthoreovirus (PRV) is an emergent virus in salmon aquaculture belonging to the family Reoviridae. PRV is associated with a growing list of pathological conditions including heart and skeletal inflammatio...

    Authors: Molly J. T. Kibenge, Yingwei Wang, Nick Gayeski, Alexandra Morton, Kurt Beardslee, Bill McMillan and Frederick S. B. Kibenge

    Citation: Virology Journal 2019 16:41

    Content type: Research

    Published on:

    The Correction to this article has been published in Virology Journal 2019 16:60

  33. Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, are a significant cause of enteritis, pneumonia, polioencephalomyelitis and reproductive disorders in pigs. Howev...

    Authors: Tingting Zhao, Li Cui, Xiangqian Yu, Zhonghai Zhang, Xiaojuan Shen and Xiuguo Hua

    Citation: Virology Journal 2019 16:37

    Content type: Research

    Published on:

  34. Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. VHSV isolates are cl...

    Authors: Shamila Yusuff, Gael Kurath, Min Sun Kim, Tarin M. Tesfaye, Jie Li, Douglas G. McKenney and Vikram N. Vakharia

    Citation: Virology Journal 2019 16:31

    Content type: Research

    Published on:

  35. Canine distemper virus (CDV), currently termed Canine morbillivirus, is an extremely contagious disease that affects dogs. It is identified as a multiple cell tropism pathogen, and its host range includes a vast ...

    Authors: Santiago Rendon-Marin, Renata da Fontoura Budaszewski, Cláudio Wageck Canal and Julian Ruiz-Saenz

    Citation: Virology Journal 2019 16:30

    Content type: Review

    Published on:

  36. Autophagy is an essential process in eukaryotic cells in which autophagosomes form to deliver cellular organelles and long-lived proteins to lysosomes for degradation. Many studies have recently identified the...

    Authors: Wei Zhang, Keren Chen, Yang Guo, Yaosheng Chen and Xiaohong Liu

    Citation: Virology Journal 2019 16:13

    Content type: Research

    Published on:

  37. The avian infectious bronchitis virus (IBV) remains a significant source of loss in the poultry industry and early diagnosis is required to prevent the disease from spreading. This study examined the combined ...

    Authors: Paula Fonseca Finger, Michele Soares Pepe, Luana Alves Dummer, Carolina Georg Magalhães, Clarissa Caetano de Castro, Silvia de Oliveira Hübner, Fábio Pereira Leivas Leite, Giseli Aparecida Ritterbusch, Paulo Augusto Esteves and Fabricio Rochedo Conceição

    Citation: Virology Journal 2018 15:189

    Content type: Research

    Published on:

  38. Porcine reproductive and respiratory syndrome virus(PRRSV) is an important immunosuppressive virus which can suppresses infected cells proliferation. In this work, we examined PRRSV ability to manipulate cell ...

    Authors: Linlin Song, Ximeng Han, Cunyu Jia, Xin Zhang, Yunjie Jiao, Taofeng Du, Shuqi Xiao, Julian A. Hiscox, En-Min Zhou and Yang Mu

    Citation: Virology Journal 2018 15:169

    Content type: Research

    Published on:

  39. A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of a...

    Authors: Huanan Wang, Feng Cong, Jianchi Guan, Li Xiao, Yujun Zhu, Yuexiao Lian, Ren Huang, Meili Chen and Pengju Guo

    Citation: Virology Journal 2018 15:146

    Content type: Methodology

    Published on:

  40. Duck Tembusu virus (DTMUV), a pathogenic flavivirus, emerged in China since 2010 and causing huge economic loss in the Chinese poultry industry. Although several vaccines have been reported to control DTMUV di...

    Authors: Jingyu Tang, Zhuangli Bi, Mingyang Ding, Dongdong Yin, Jie Zhu, Li Zhang, Qiuhong Miao, Yingqi Zhu, Guijun Wang and Guangqing Liu

    Citation: Virology Journal 2018 15:140

    Content type: Research

    Published on:

  41. Canine distemper (CD) is a highly contagious, systemic, viral disease of dogs seen worldwide. Despite intensive vaccination in developed countries, recent reports suggest both the re-emergence and increased ac...

    Authors: Eman Anis, Teresa K. Newell, Neil Dyer and Rebecca P. Wilkes

    Citation: Virology Journal 2018 15:118

    Content type: Research

    Published on:

  42. Bovine viral diarrhea virus (BVDV) causes significant economic losses worldwide in the cattle industry through decrease in productive performance and immunosuppression of animals in herds. Recent studies condu...

    Authors: Kyung-Hyun Lee, Du-Gyeong Han, Suhee Kim, Eun-Jin Choi and Kyoung-Seong Choi

    Citation: Virology Journal 2018 15:115

    Content type: Research

    Published on:

  43. Reovirus type-3 infections cause severe pathologies in young mice and thus influence animal experiments in many ways. Therefore, the Federation of Laboratory Animal Science Associations (FELASA) recommends an ...

    Authors: Felix Fingas, Daniela Volke, Petra Bielefeldt, Rayk Hassert and Ralf Hoffmann

    Citation: Virology Journal 2018 15:114

    Content type: Research

    Published on:

  44. Emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) in North America, Asia and Europe has caused severe economic loss to the global swine industry. However, the virome of PEDV infected pigs an...

    Authors: Qi Chen, Leyi Wang, Ying Zheng, Jianqiang Zhang, Baoqing Guo, Kyoung-Jin Yoon, Phillip C. Gauger, Karen M. Harmon, Rodger G. Main and Ganwu Li

    Citation: Virology Journal 2018 15:95

    Content type: Research

    Published on:

  45. Vesiviruses (family Caliciviridae) had been shown capable of invading a variety of host species, raising concern of their zoonotic potential. Since the 1980’s, several canine caliciviruses (CaCV) isolates have be...

    Authors: Leonard N. Binn, Erica A. Norby, Ruth H. Marchwicki, Richard G. Jarman, Paul B. Keiser and Jun Hang

    Citation: Virology Journal 2018 15:39

    Content type: Research

    Published on:

  46. Porcine epidemic diarrhea (PED) is a lethal infectious disease in suckling piglets with symptoms including watery diarrhea caused by PED virus (PEDV). Since the late 1990’s, live vaccines based on genogroup 1 ...

    Authors: Tetsuo Sato, Kazuki Oroku, Yoshiyuki Ohshima, Yoshiaki Furuya and Chihiro Sasakawa

    Citation: Virology Journal 2018 15:28

    Content type: Research

    Published on:

  47. Virulent Newcastle disease virus (NDV, avian Avulavirus-1, APMV-1) induces a highly contagious and lethal systemic disease in gallinaceous poultry. APMV-1 antibody detection is used for surveillance and to con...

    Authors: Na Zhao, Christian Grund, Martin Beer and Timm C. Harder

    Citation: Virology Journal 2018 15:8

    Content type: Research

    Published on:

  48. Porcine reproductive and respiratory syndrome virus (PRRSV) has been epidemic more than 30 years in America and 20 years in China. It is still one of the most important causative agents to the worldwide swine ...

    Authors: Zhenhua Guo, Xin-xin Chen, Rui Li, Songlin Qiao and Gaiping Zhang

    Citation: Virology Journal 2018 15:2

    Content type: Review

    Published on:

  49. DNA-launched infectious system is a useful tool with high rescue efficiency that allows the introduction of mutations in specific positions to investigate the function of an individual viral element. Rescued v...

    Authors: Junhao Chen, Ruihua Zhang, Shaoli Lin, Pengfei Li, Jingjing Lan, Zhijing Xie, Yu Wang and Shijin Jiang

    Citation: Virology Journal 2017 14:212

    Content type: Research

    Published on: