Negative-strand RNA viruses

Section edited by Andrew Easton

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  1. Research

    Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection

    Host proteases have been shown to play important roles in many viral activities such as entry, uncoating, viral protein production and disease induction. Therefore, these cellular proteases are putative target...

    Winke Van der Gucht, Annelies Leemans, Marjorie De Schryver, Annick Heykers, Guy Caljon, Louis Maes, Paul Cos and Peter L. Delputte

    Virology Journal 2017 14:157

    Published on: 17 August 2017

  2. Research

    Comparison of serological assays to titrate Hantaan and Seoul hantavirus-specific antibodies

    Hantaan and Seoul viruses, in the Hantavirus genus, are known to cause hemorrhagic fever with renal syndrome (HFRS). The plaque reduction neutralization test (PRNT), as conventional neutralization test for han...

    Weihong Li, Shouchun Cao, Quanfu Zhang, Jiandong Li, Shuo Zhang, Wei Wu, Jing Qu, Chuan Li, Mifang Liang and Dexin Li

    Virology Journal 2017 14:133

    Published on: 18 July 2017

  3. Short Paper

    Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

    Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of...

    Mako Yanai, Madoka Sakai, Akiko Makino and Keizo Tomonaga

    Virology Journal 2017 14:126

    Published on: 11 July 2017

  4. Research

    Comparison of the protective efficacy between single and combination of recombinant adenoviruses expressing complete and truncated glycoprotein, and nucleoprotein of the pathogenic street rabies virus in mice

    Rabies is an important viral zoonosis that causes acute encephalitis and death in mammals. To date, several recombinant vaccines have been developed based on G protein, which is considered to be the main antig...

    Ha-Hyun Kim, Dong-Kun Yang, Jin-Ju Nah, Jae-Young Song and In-Soo Cho

    Virology Journal 2017 14:122

    Published on: 24 June 2017

  5. Research

    Cross-border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China

    Rabies is an important but underestimated threat to public health, with most cases reported in Asia. Since 2000, a new epidemic wave of rabies has emerged in Yunnan Province, southwestern China, which borders ...

    Yuzhen Zhang, Bram Vrancken, Yun Feng, Simon Dellicour, Qiqi Yang, Weihong Yang, Yunzhi Zhang, Lu Dong, Oliver G. Pybus, Hailin Zhang and Huaiyu Tian

    Virology Journal 2017 14:102

    Published on: 3 June 2017

  6. Methodology

    A robust and cost-effective approach to sequence and analyze complete genomes of small RNA viruses

    Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic acids. The use of sequence-independent amplification of viral nucleic acids without utilization of target-specific primers provides adva...

    Kiril M. Dimitrov, Poonam Sharma, Jeremy D. Volkening, Iryna V. Goraichuk, Abdul Wajid, Shafqat Fatima Rehmani, Asma Basharat, Ismaila Shittu, Tony M. Joannis, Patti J. Miller and Claudio L. Afonso

    Virology Journal 2017 14:72

    Published on: 7 April 2017

  7. Methodology

    Development of real-time and lateral flow strip reverse transcription recombinase polymerase Amplification assays for rapid detection of peste des petits ruminants virus

    Peste des petits ruminants (PPR) is an economically important, Office International des Epizooties (OIE) notifiable, transboundary viral disease of small ruminants such as sheep and goat. PPR virus (PPRV), a n...

    Yang Yang, Xiaodong Qin, Yiming Song, Wei Zhang, Gaowei Hu, Yongxi Dou, Yanmin Li and Zhidong Zhang

    Virology Journal 2017 14:24

    Published on: 7 February 2017

  8. Research

    A DNA vaccine encoding the viral hemorrhagic septicemia virus genotype IVb glycoprotein confers protection in muskellunge (Esox masquinongy), rainbow trout (Oncorhynchus mykiss), brown trout (Salmo trutta), and lake trout (Salvelinus namaycush)

    The viral hemorrhagic septicemia virus (VHSV) is one of the most serious fish pathogens. In 2003, a novel sublineage (genotype IVb) of this deadly virus emerged in the Great Lakes basin causing serious fish ki...

    Isaac F. Standish, Elena V. Millard, Travis O. Brenden and Mohamed Faisal

    Virology Journal 2016 13:203

    Published on: 2 December 2016

  9. Review

    Host cytoskeleton in respiratory syncytial virus assembly and budding

    Respiratory syncytial virus (RSV) is one of the major pathogens responsible for lower respiratory tract infections (LRTI) in young children, the elderly, and the immunosuppressed. Currently, there are no antiv...

    Shadi Shahriari, James Gordon and Reena Ghildyal

    Virology Journal 2016 13:161

    Published on: 26 September 2016

  10. Research

    Common position of indels that cause deviations from canonical genome organization in different measles virus strains

    The canonical genome organization of measles virus (MV) is characterized by total size of 15 894 nucleotides (nts) and defined length of every genomic region, both coding and non-coding. Only rarely have repor...

    Jelena Ivancic-Jelecki, Anamarija Slovic, Maja Šantak, Goran Tešović and Dubravko Forcic

    Virology Journal 2016 13:134

    Published on: 29 July 2016

  11. Short report

    Differences in viral load among human respiratory syncytial virus genotypes in hospitalized children with severe acute respiratory infections in the Philippines

    Human respiratory syncytial virus (HRSV) is a leading viral etiologic agent of pediatric lower respiratory infections, including bronchiolitis and pneumonia. Two antigenic subgroups, HRSV-A and B, each contain...

    Francois Marie Ngako Kadji, Michiko Okamoto, Yuki Furuse, Raita Tamaki, Akira Suzuki, Irene Lirio, Clyde Dapat, Rungnapa Malasao, Mariko Saito, Gay Anne Granada Pedrera-Rico, Veronica Tallo, Socorro Lupisan, Mayuko Saito and Hitoshi Oshitani

    Virology Journal 2016 13:113

    Published on: 27 June 2016

  12. Research

    Development of real-time reverse transcriptase qPCR assays for the detection of Punta Toro virus and Pichinde virus

    Research with high biocontainment pathogens such as Rift Valley fever virus (RVFV) and Lassa virus (LASV) is expensive, potentially hazardous, and limited to select institutions. Surrogate pathogens such as Pu...

    Christopher P. Stefan, Kitty Chase, Susan Coyne, David A. Kulesh, Timothy D. Minogue and Jeffrey W. Koehler

    Virology Journal 2016 13:54

    Published on: 31 March 2016

  13. Research

    Actin- and clathrin-dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus

    Respiratory syncytial virus (RSV) can cause recurrent and severe respiratory tract infections. Cytoskeletal proteins are often involved during viral infections, either for cell entry or the initiation of the i...

    Jop Jans, Hicham elMoussaoui, Ronald de Groot, Marien I. de Jonge and Gerben Ferwerda

    Virology Journal 2016 13:52

    Published on: 22 March 2016

  14. Research

    Protective efficacy of a recombinant Newcastle disease virus expressing glycoprotein of vesicular stomatitis virus in mice

    Vesicular stomatitis virus (VSV) causes severe losses to the animal husbandry industry. In this study, a recombinant Newcastle disease virus (NDV) expressing the glycoprotein (G) of VSV (rL-VSV-G) was construc...

    Minmin Zhang, Jinying Ge, Xiaofang Li, Weiye Chen, Xijun Wang, Zhiyuan Wen and Zhigao Bu

    Virology Journal 2016 13:31

    Published on: 24 February 2016

  15. Short report

    Fugong virus, a novel hantavirus harbored by the small oriental vole (Eothenomys eleusis) in China

    Rodents are natural reservoirs of hantaviruses, which cause two disease types: hemorrhagic fever with renal syndrome in Eurasia and hantavirus pulmonary syndrome in North America. Hantaviruses related human ca...

    Xing-Yi Ge, Wei-Hong Yang, Hong Pan, Ji-Hua Zhou, Xi Han, Guang-Jian Zhu, James S. Desmond, Peter Daszak, Zheng-Li Shi and Yun-Zhi Zhang

    Virology Journal 2016 13:27

    Published on: 16 February 2016

    The Erratum to this article has been published in Virology Journal 2016 13:75

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