Positive-strand RNA viruses

Section edited by Suresh Mahalingam

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  1. Research

    Prevalence of human pegivirus-1 and sequence variability of its E2 glycoprotein estimated from screening donors of fetal stem cell-containing material

    Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV). The E2 glycoprotein of HPgV-1 is the principl...

    Yakov Vitrenko, Iryna Kostenko, Kateryna Kulebyakina and Khrystyna Sorochynska

    Virology Journal 2017 14:167

    Published on: 31 August 2017

  2. Research

    Chikungunya virus infection in Cynomolgus macaques following Intradermal and aerosol exposure

    Chikungunya virus (CHIKV) is transmitted via mosquito bite and potentially by aerosol, causing chikungunya fever and arthritic disease in humans. There are currently no licensed vaccines or antiviral therapeut...

    Chris M. Cirimotich, Eric M. Vela, Jennifer Garver, Roy E. Barnewall, Brian D. Miller, Gabriel T. Meister and James V. Rogers

    Virology Journal 2017 14:135

    Published on: 20 July 2017

  3. Research

    Genome-wide analysis of codon usage bias in Bovine Coronavirus

    Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important econo...

    Matías Castells, Matías Victoria, Rodney Colina, Héctor Musto and Juan Cristina

    Virology Journal 2017 14:115

    Published on: 17 June 2017

  4. Research

    Complete genome sequence of T’Ho virus, a novel putative flavivirus from the Yucatan Peninsula of Mexico

    We previously reported the discovery of a novel, putative flavivirus designated T’Ho virus in Culex quinquefasciatus mosquitoes in the Yucatan Peninsula of Mexico. A 1358-nt region of the NS5 gene was amplified a...

    Thomas Briese, Maria A. Loroño-Pino, Julian E. Garcia-Rejon, Jose A. Farfan-Ale, Carlos Machain-Williams, Karin S. Dorman, W. Ian Lipkin and Bradley J. Blitvich

    Virology Journal 2017 14:110

    Published on: 12 June 2017

  5. Research

    Zika vector transmission risk in temperate Australia: a vector competence study

    Zika virus is an emerging pathogen of global importance. It has been responsible for recent outbreaks in the Americas and in the Pacific region. This study assessed five different mosquito species from the tem...

    Jean-Bernard Duchemin, Peter T. Mee, Stacey E. Lynch, Ravikiran Vedururu, Lee Trinidad and Prasad Paradkar

    Virology Journal 2017 14:108

    Published on: 9 June 2017

  6. Research

    Detection of alpha- and betacoronaviruses in rodents from Yunnan, China

    Rodents represent the most diverse mammals on the planet and are important reservoirs of human pathogens. Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in...

    Xing-Yi Ge, Wei-Hong Yang, Ji-Hua Zhou, Bei Li, Wei Zhang, Zheng-Li Shi and Yun-Zhi Zhang

    Virology Journal 2017 14:98

    Published on: 26 May 2017

  7. Review

    Inhibitors compounds of the flavivirus replication process

    Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are...

    Leidy L. García, Leonardo Padilla and Jhon C. Castaño

    Virology Journal 2017 14:95

    Published on: 15 May 2017

  8. Research

    A guinea pig model of Zika virus infection

    Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemic of Zika virus (ZIKV). Here we report that immunocompetent guinea pigs are susceptible to infection by a ...

    Mukesh Kumar, Keeton K. Krause, Francine Azouz, Eileen Nakano and Vivek R. Nerurkar

    Virology Journal 2017 14:75

    Published on: 11 April 2017

  9. Short report

    Viral and serological kinetics in Zika virus-infected patients in South Korea

    Zika virus is a mosquito-borne flavivirus that causes clinical symptoms similar to those observed in dengue and chikungunya virus infections. The Korea Centers for Disease Control and Prevention initiated labo...

    Young Eui Jeong, Go-Woon Cha, Jung Eun Cho, Eun Ju Lee, Youngmee Jee and Won-Ja Lee

    Virology Journal 2017 14:70

    Published on: 7 April 2017

  10. Research

    Identification of host cellular proteins that interact with the M protein of a highly pathogenic porcine reproductive and respiratory syndrome virus vaccine strain

    The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) continues to pose one of the greatest threats to the swine industry. M protein is the most conserved and important structura...

    Qian Wang, Yanwei Li, Hong Dong, Li Wang, Jinmei Peng, Tongqing An, Xufu Yang, Zhijun Tian and Xuehui Cai

    Virology Journal 2017 14:39

    Published on: 22 February 2017

  11. Research

    Involvement of fatty acid synthase in dengue virus infection

    The mosquito transmitted Dengue virus (DENV) remains a significant public health problem in many tropical and subtropical countries. Increasing evidence has suggested that during the infection process cellular li...

    Natthida Tongluan, Suwipa Ramphan, Phitchayapak Wintachai, Janthima Jaresitthikunchai, Sarawut Khongwichit, Nitwara Wikan, Supoth Rajakam, Sutee Yoksan, Nuttaporn Wongsiriroj, Sittiruk Roytrakul and Duncan R. Smith

    Virology Journal 2017 14:28

    Published on: 13 February 2017

  12. Research

    Coxsackievirus B4 vertical transmission in a murine model

    Life-threatening infections with type B Coxsackieviruses (CV-B) are frequently encountered among newborns and are partly attributed to vertically-transmitted virus. Our current study investigates this alternat...

    Hela Jaïdane, Aymen Halouani, Habib Jmii, Firas Elmastour, Moncef Mokni and Mahjoub Aouni

    Virology Journal 2017 14:16

    Published on: 31 January 2017

  13. Research

    Sequence diversity of dengue virus type 2 in brain and thymus of infected interferon receptor ko mice: implications for dengue virulence

    We previously reported that a clinical isolate of dengue virus (DENV) is capable of causing acute-phase systemic infection in mice harboring knockouts of the genes encoding type-I and -II interferon IFN recept...

    Priya Dhole, Emi E. Nakayama, Akatsuki Saito, Kriengsak Limkittikul, Supranee Phanthanawiboon, Tatsuo Shioda and Takeshi Kurosu

    Virology Journal 2016 13:199

    Published on: 30 November 2016

  14. Methodology

    Analytical characteristics and comparative evaluation of Aptima HIV-1 Quant Dx assay with Ampliprep/COBAS TaqMan HIV-1 test v2.0

    Quantitation of HIV-RNA is critically important for diagnosis, prognosis, treatment, monitoring and assessment of infectivity in HIV-1 infection. The objective of this study was to assess performance character...

    Angelos. Hatzakis, Helen Papachristou, Sangeetha J. Nair, Jacqueline Fortunko, Tracy Foote, HeeCheol Kim, Tashi L. Peling and Andrew J. Worlock

    Virology Journal 2016 13:176

    Published on: 21 October 2016

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