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  1. Research

    Putative progressive and abortive feline leukemia virus infection outcomes in captive jaguarundis (Puma yagouaroundi)

    Feline leukemia virus (FeLV) is an exogenous gammaretrovirus of domestic cats (Felis catus) and some wild felids. The outcomes of FeLV infection in domestic cats vary according to host susceptibility, virus strai...

    Claudia Filoni, A. Katrin Helfer-Hungerbuehler, José Luiz Catão-Dias, Mara Cristina Marques, Luciana Neves Torres, Manfred Reinacher and Regina Hofmann-Lehmann

    Virology Journal 2017 14:226

    Published on: 17 November 2017

  2. Research

    Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

    Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out ...

    Karolin Meixenberger, Kaveh Pouran Yousef, Maureen Rebecca Smith, Sybille Somogyi, Stefan Fiedler, Barbara Bartmeyer, Osamah Hamouda, Norbert Bannert, Max von Kleist and Claudia Kücherer

    Virology Journal 2017 14:223

    Published on: 14 November 2017

  3. Research

    A cheap and open HIV viral load technique applicable in routine analysis in a resource limited setting with a wide HIV genetic diversity

    HIV infection in Cameroon is characterized by a great viral diversity with all HIV-1 groups (M, N, O, and P) and HIV-2 in circulation. HIV group determination is very important if tailored viral load analysis ...

    Elodie Téclaire Ngo-Malabo, Paul Alain Ngoupo T., Martin Zekeng, Valérie Ngono, Laure Ngono, Serge Alain Sadeuh-Mba, Richard Njouom and Anfumbom Kfutwah

    Virology Journal 2017 14:224

    Published on: 14 November 2017

  4. Correction

    Correction to: Development of molecular confirmation tools for swift and easy rabies diagnostics

    After publication of the article [1], it has been brought to our attention that an incorrect genetic sequence has been cited. On page 4, paragraph 1 the following sequence is cited “ATG GAT GCC GAC AAG ATT GTM...

    Kore Schlottau, Conrad M. Freuling, Thomas Müller, Martin Beer and Bernd Hoffmann

    Virology Journal 2017 14:225

    Published on: 14 November 2017

    The original article was published in Virology Journal 2017 14:184

  5. Short Report

    Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations

    Porcine circovirus type 3 (PCV3), as an emerging circovirus species, was reported to be widely circulating in the United States, China, South Korea and Poland. Previous studies revealed that PCV3 was mainly co...

    Shao-Lun Zhai, Xia Zhou, He Zhang, Ben M. Hause, Tao Lin, Runxia Liu, Qin-Ling Chen, Wen-Kang Wei, Dian-Hong Lv, Xiao-Hui Wen, Feng Li and Dan Wang

    Virology Journal 2017 14:222

    Published on: 13 November 2017

  6. Research

    An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced

    Genetically modified adenoviruses (Ad) with preferential replications in tumor cells have been examined for a possible clinical applicability as an anti-cancer agent. A simple method to detect viral and cellul...

    Takao Morinaga, Thảo Thi Thanh Nguyễn, Boya Zhong, Michiko Hanazono, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima and Masatoshi Tagawa

    Virology Journal 2017 14:219

    Published on: 10 November 2017

  7. Research

    Association of IFITM3 rs12252 polymorphisms, BMI, diabetes, and hypercholesterolemia with mild flu in an Iranian population

    IFITM3 has been suggested to be associated with infection in some ethnic groups. Diabetes and hypercholesterolemia are also important clinical conditions that can predispose individual...

    Parvaneh Mehrbod, Sana Eybpoosh, Fatemeh Fotouhi, Hadiseh Shokouhi Targhi, Vahideh Mazaheri and Behrokh Farahmand

    Virology Journal 2017 14:218

    Published on: 9 November 2017

  8. Research

    ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells

    The Zika virus (ZIKV) is a mosquito-borne flavivirus that causes microcephaly and Guillain-Barré syndrome in infected individuals. To obtain insights into the mechanism of ZIKV infection and pathogenesis, we a...

    Benxia Hu, Yongxia Huo, Liping Yang, Guijun Chen, Minhua Luo, Jinlong Yang and Jumin Zhou

    Virology Journal 2017 14:217

    Published on: 7 November 2017

  9. Short Report

    Lack of cytomegalovirus detection in human glioma

    Gliomas are the most common brain tumors and include a variety of histologic types and grades of malignancy. They arise from glial cells and represent approximately 70% of the primary brain tumors. According t...

    Araceli Garcia-Martinez, Cristina Alenda, Esperanza Irles, Enrique Ochoa, Teresa Quintanar, Alvaro Rodriguez-Lescure, Jose L. Soto and Victor M. Barbera

    Virology Journal 2017 14:216

    Published on: 7 November 2017

  10. Research

    Fraction of high-grade cervical intraepithelial lesions attributable to genotypes targeted by a nonavalent HPV vaccine in Galicia, Spain

    Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The obje...

    S. Perez, A. Iñarrea, R. Pérez-Tanoira, M. Gil, E. López-Díez, O. Valenzuela, M. Porto, L. Alberte-Lista, M. A. Peteiro-Cancelo, A. Treinta, R. Carballo, M. C. Reboredo, M. E. Alvarez-Argüelles and M. J. Purriños

    Virology Journal 2017 14:214

    Published on: 6 November 2017

  11. Research

    Construction and characterization of an improved DNA-launched infectious clone of duck hepatitis a virus type 1

    DNA-launched infectious system is a useful tool with high rescue efficiency that allows the introduction of mutations in specific positions to investigate the function of an individual viral element. Rescued v...

    Junhao Chen, Ruihua Zhang, Shaoli Lin, Pengfei Li, Jingjing Lan, Zhijing Xie, Yu Wang and Shijin Jiang

    Virology Journal 2017 14:212

    Published on: 3 November 2017

  12. Methodology

    Validation of a pan-orthopox real-time PCR assay for the detection and quantification of viral genomes from nonhuman primate blood

    In 1980, smallpox disease was eradicated from nature and Variola virus, the etiological agent of smallpox, was confined to two laboratories, one located in Russia (Moscow) later moved to VECTOR (Novosibirsk, Sibe...

    Eric M. Mucker, Christopher Hartmann, Donna Hering, Wendy Giles, David Miller, Robert Fisher and John Huggins

    Virology Journal 2017 14:210

    Published on: 3 November 2017

  13. Research

    HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells

    Condyloma acuminatum, infected by low-risk human papillomaviruses (e.g., HPV6 and HPV11), is one of the most widespread sexually transmitted diseases. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide...

    Yongfang Wang, Xinyu Li, Shasha Song, Yang Sun, Jiafen Zhang, Changming Yu and Wei Chen

    Virology Journal 2017 14:211

    Published on: 3 November 2017

  14. Research

    Investigation of antiviral state mediated by interferon-inducible transmembrane protein 1 induced by H9N2 virus and inactivated viral particle in human endothelial cells

    Endothelial cells are believed to play an important role in response to virus infection. Our previous microarray analysis showed that H9N2 virus infection and inactivated viral particle inoculation increased t...

    Bo Feng, Lihong Zhao, Wei Wang, Jianfang Wang, Hongyan Wang, Huiqin Duan, Jianjun Zhang and Jian Qiao

    Virology Journal 2017 14:213

    Published on: 3 November 2017

  15. Review

    Epidemiology and genetic diversity of bovine leukemia virus

    Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses....

    Meripet Polat, Shin-nosuke Takeshima and Yoko Aida

    Virology Journal 2017 14:209

    Published on: 2 November 2017

  16. Research

    A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca)

    Polyomaviruses infect a wide variety of mammalian and avian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction.

    Dunwu Qi, Tongling Shan, Zhijian Liu, Xutao Deng, Zhihe Zhang, Wenlei Bi, Jacob Robert Owens, Feifei Feng, Lisong Zheng, Feng Huang, Eric Delwart, Rong Hou and Wen Zhang

    Virology Journal 2017 14:207

    Published on: 27 October 2017

  17. Research

    A comparative study of multiple clinical enterovirus 71 isolates and evaluation of cross protection of inactivated vaccine strain FY-23 K-B in vitro

    Enterovirus 71 (EV71) is one of the causative agents of hand, foot and mouth disease, which mostly affects infants and children and leads to severe neurological diseases. Vaccination offers the best option for...

    Ting Yang, Hua Li, Lei Yue, Xia Song, Tianhong Xie, Shaohui Ma, Huaqing Meng, Ye Zhang, Xin He, Runxiang Long, Rong Yang, Fangyu Luo, Zhongping Xie and Qihan Li

    Virology Journal 2017 14:206

    Published on: 26 October 2017

  18. Research

    Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice

    Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the out...

    Weiwei Gai, Xuexing Zheng, Chong Wang, Hualei Wang, Yongkun Zhao, Qi Wang, Gary Wong, Weijiao Zhang, Na Feng, Boning Qiu, Hang Chi, Nan Li, Tiecheng Wang, Yuwei Gao, Junjie Shan, Songtao Yang…

    Virology Journal 2017 14:204

    Published on: 25 October 2017

  19. Research

    The dose of HBV genome contained plasmid has a great impact on HBV persistence in hydrodynamic injection mouse model

    Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-H...

    Lei Li, Sheng Li, Yun Zhou, Lu Yang, Di Zhou, Yan Yang, Mengji Lu, Dongliang Yang and Jingjiao Song

    Virology Journal 2017 14:205

    Published on: 25 October 2017

  20. Research

    Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants

    The pathogenesis of acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB) is not well understood. The aim of this study was to investigate whether there is an association between HBV polymerase (P...

    Shan Gao, Shivali S. Joshi, Carla Osiowy, Y. Chen, Carla S. Coffin and Z-P. Duan

    Virology Journal 2017 14:203

    Published on: 24 October 2017

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