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  1. Research

    Comparison of the protective efficacy between single and combination of recombinant adenoviruses expressing complete and truncated glycoprotein, and nucleoprotein of the pathogenic street rabies virus in mice

    Rabies is an important viral zoonosis that causes acute encephalitis and death in mammals. To date, several recombinant vaccines have been developed based on G protein, which is considered to be the main antig...

    Ha-Hyun Kim, Dong-Kun Yang, Jin-Ju Nah, Jae-Young Song and In-Soo Cho

    Virology Journal 2017 14:122

    Published on: 24 June 2017

  2. Short Report

    Chorioallantoic membranes of embryonated chicken eggs as an alternative system for isolation of equine influenza virus

    Influenza virus isolation in embryonated chicken eggs (ECEs) is not applicable for rapid diagnosis, however it allows the recovery and propagation of the viable virus. A low number of infectious virus particle...

    Ilona Marcelina Gora, Malgorzata Kwasnik, Jan Franciszek Zmudzinski and Wojciech Rozek

    Virology Journal 2017 14:120

    Published on: 21 June 2017

  3. Short Report

    Variability in P1 gene redefines phylogenetic relationships among cassava brown streak viruses

    Cassava brown streak disease is emerging as the most important viral disease of cassava in Africa, and is consequently a threat to food security. Two distinct species of the genus Ipomovirus (family Potyviridae) ...

    Willard Mbewe, Fred Tairo, Peter Sseruwagi, Joseph Ndunguru, Siobain Duffy, Ssetumba Mukasa, Ibrahim Benesi, Samar Sheat, Marianne Koerbler and Stephan Winter

    Virology Journal 2017 14:118

    Published on: 20 June 2017

  4. Research

    Epitope mapping and characterization of a novel Nsp10-specific monoclonal antibody that differentiates genotype 2 PRRSV from genotype 1 PRRSV

    Porcine reproductive and respiratory syndrome virus (PRRSV), the causative agent of PRRS, has two distinct and highly diverse genotypes (genotype 1 and genotype 2) in the field. Accurate diagnosis and differen...

    Zhibang Zhang, Xuexia Wen, Jianguo Dong, Xinna Ge, Lei Zhou, Hanchun Yang and Xin Guo

    Virology Journal 2017 14:116

    Published on: 19 June 2017

  5. Research

    Genome-wide analysis of codon usage bias in Bovine Coronavirus

    Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important econo...

    Matías Castells, Matías Victoria, Rodney Colina, Héctor Musto and Juan Cristina

    Virology Journal 2017 14:115

    Published on: 17 June 2017

  6. Research

    Cyclophilin B facilitates the replication of Orf virus

    Viruses interact with host cellular factors to construct a more favourable environment for their efficient replication. Expression of cyclophilin B (CypB), a cellular peptidyl-prolyl cis-trans isomerase (PPIase),...

    Kui Zhao, Jida Li, Wenqi He, Deguang Song, Ximu Zhang, Di Zhang, Yanlong Zhou and Feng Gao

    Virology Journal 2017 14:114

    Published on: 15 June 2017

  7. Short report

    Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array

    Our next generation sequencing (NGS)-based human papillomavirus (HPV) genotyping assay showed a high degree of concordance with the Roche Linear Array (LA) with as little as 1.25 ng formalin-fixed paraffin-emb...

    Rebecca G. Nowak, Nicholas P. Ambulos, Lisa M. Schumaker, Trevor J. Mathias, Ruth A. White, Jennifer Troyer, David Wells, Manhattan E. Charurat, Søren M. Bentzen and Kevin J. Cullen

    Virology Journal 2017 14:112

    Published on: 13 June 2017

  8. Research

    Complete genome sequence of T’Ho virus, a novel putative flavivirus from the Yucatan Peninsula of Mexico

    We previously reported the discovery of a novel, putative flavivirus designated T’Ho virus in Culex quinquefasciatus mosquitoes in the Yucatan Peninsula of Mexico. A 1358-nt region of the NS5 gene was amplified a...

    Thomas Briese, Maria A. Loroño-Pino, Julian E. Garcia-Rejon, Jose A. Farfan-Ale, Carlos Machain-Williams, Karin S. Dorman, W. Ian Lipkin and Bradley J. Blitvich

    Virology Journal 2017 14:110

    Published on: 12 June 2017

  9. Research

    A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

    Avian coronavirus infectious bronchitis virus (IBV) is a respiratory pathogen of chickens that causes severe economic losses in the poultry industry worldwide. Major advances in the study of the molecular biol...

    Steven J. van Beurden, Alinda J. Berends, Annika Krämer-Kühl, Dieuwertje Spekreijse, Gilles Chénard, Hans-Christian Philipp, Egbert Mundt, Peter J. M. Rottier and M. Hélène Verheije

    Virology Journal 2017 14:109

    Published on: 12 June 2017

  10. Research

    Molecular epidemiology of Avian Rotaviruses Group A and D shed by different bird species in Nigeria

    Avian rotaviruses (RVs) cause gastrointestinal diseases of birds worldwide. However, prevalence, diversity, epidemiology and phylogeny of RVs remain largely under-investigated in Africa.

    Maude Pauly, Oluwole O. Oni, Aurélie Sausy, Ademola A. Owoade, Christopher A. O. Adeyefa, Claude P. Muller, Judith M. Hübschen and Chantal J. Snoeck

    Virology Journal 2017 14:111

    Published on: 12 June 2017

  11. Research

    Zika vector transmission risk in temperate Australia: a vector competence study

    Zika virus is an emerging pathogen of global importance. It has been responsible for recent outbreaks in the Americas and in the Pacific region. This study assessed five different mosquito species from the tem...

    Jean-Bernard Duchemin, Peter T. Mee, Stacey E. Lynch, Ravikiran Vedururu, Lee Trinidad and Prasad Paradkar

    Virology Journal 2017 14:108

    Published on: 9 June 2017

  12. Case report

    Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure

    The major resistance-associated substitution for sofosbuvir (S282T) in HCV NS5B causes severe viral fitness costs and rapidly reverts back to prototype in the absence of selection pressure. Accordingly, resist...

    Andreas Walker, Sandra Filke, Nadine Lübke, Martin Obermeier, Rolf Kaiser, Dieter Häussinger, Jörg Timm and Hans H. Bock

    Virology Journal 2017 14:106

    Published on: 8 June 2017

  13. Research

    Cross-border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China

    Rabies is an important but underestimated threat to public health, with most cases reported in Asia. Since 2000, a new epidemic wave of rabies has emerged in Yunnan Province, southwestern China, which borders ...

    Yuzhen Zhang, Bram Vrancken, Yun Feng, Simon Dellicour, Qiqi Yang, Weihong Yang, Yunzhi Zhang, Lu Dong, Oliver G. Pybus, Hailin Zhang and Huaiyu Tian

    Virology Journal 2017 14:102

    Published on: 3 June 2017

  14. Research

    Virology analysis in HCV genotype 1-infected patients treated with the combination of simeprevir and TMC647055/ritonavir, with and without ribavirin, and JNJ-56914845

    In study TMC647055HPC2001, a 3-direct-acting-antiviral (DAA) regimen combining NS3/4A protease inhibitor simeprevir (SMV), non-nucleoside NS5B inhibitor TMC647055/ritonavir (RTV) and NS5A inhibitor JNJ-5691484...

    Leen Vijgen, Kim Thys, An Vandebosch, Pieter Van Remoortere, René Verloes and Sandra De Meyer

    Virology Journal 2017 14:101

    Published on: 31 May 2017

  15. Research

    Development and application of triple antibody sandwich enzyme-linked immunosorbent assays for begomovirus detection using monoclonal antibodies against Tomato yellow leaf curl Thailand virus

    Tomato yellow leaf curl Thailand virus, TYLCTHV, is a begomovirus that causes severe losses of tomato crops in Thailand as well as several countries in Southeast and East Asia. The dev...

    Channarong Seepiban, Saengsoon Charoenvilaisiri, Nuchnard Warin, Anjana Bhunchoth, Namthip Phironrit, Bencharong Phuangrat, Orawan Chatchawankanphanich, Supat Attathom and Oraprapai Gajanandana

    Virology Journal 2017 14:99

    Published on: 30 May 2017

  16. Research

    First study conducted in Northern India that identifies group C rotavirus as the etiological agent of severe diarrhea in children in Delhi

    Group C Rotavirus (RVC) is an enteric pathogen responsible for acute gastroenteritis in children and adults globally. At present there are no surveillance studies on group C Rotaviruses in India and therefore ...

    Vasundhara Razdan Tiku, Baoming Jiang, Praveen Kumar, Satender Aneja, Arvind Bagga, Maharaj Kishen Bhan and Pratima Ray

    Virology Journal 2017 14:100

    Published on: 30 May 2017

  17. Research

    Detection of alpha- and betacoronaviruses in rodents from Yunnan, China

    Rodents represent the most diverse mammals on the planet and are important reservoirs of human pathogens. Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in...

    Xing-Yi Ge, Wei-Hong Yang, Ji-Hua Zhou, Bei Li, Wei Zhang, Zheng-Li Shi and Yun-Zhi Zhang

    Virology Journal 2017 14:98

    Published on: 26 May 2017

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