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  1. N6-methyladenosine (m6A) modification is the most prevalent internal modification of eukaryotic mRNA modulating gene expression. m6A modification is a dynamic reversible process regulated by three protein grou...

    Authors: Fang Wu, Wenzhao Cheng, Feiyuan Zhao, Mingqing Tang, Yong Diao and Ruian Xu

    Citation: Virology Journal 2019 16:133

    Content type: Review

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  2. Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of this viral group in human hosts remain unclear. Ou...

    Authors: Hany K. Soliman, Mohamed Abouelhoda, Mahmoud N. El Rouby, Ola S. Ahmed, G. Esmat, Zeinab K. Hassan, Mohammed M. Hafez, Dina Ahmed Mehaney, Manojkumar Selvaraju, Rania Kamal Darwish, Yehia A. Osman and Abdel-Rahman N. Zekri

    Citation: Virology Journal 2019 16:132

    Content type: Case Report

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  3. In Oman tobacco (Nicotiana tabacum; family Solanaceae) is a minor crop, which is produced only for local consumption. In 2015, tobacco plants exhibiting severe downward leaf curling, leaf thickening, vein swellin...

    Authors: Muhammad Shafiq Shahid, Muhammad Shafiq, Amir Raza, Abdullah M. Al-Sadi and Rob W. Briddon

    Citation: Virology Journal 2019 16:131

    Content type: Research

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  4. MicroRNAs (miRNAs) are a class of 21–24 nucleotide endogenous non-coding small RNAs that play important roles in plant development and defense responses to biotic and abiotic stresses. Tobacco curly shoot viru...

    Authors: Jiang Du, Gentu Wu, Zhongpiao Zhou, Jiayuan Zhang, Mingjun Li, Miao Sun, Kairong Jiang and Ling Qing

    Citation: Virology Journal 2019 16:130

    Content type: Research

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  5. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever that was first described in China in 2011. We report a patient who died of Severe fever with thrombocytopenia syndrome virus (SF...

    Authors: Yi Sun, Bin Guo, Hao Yan, Ai Lan Wu, Wen Wu Yao, Kang Chen, Jun Hang Pan, Zhao Xia Li, Hai Yan Mao and Yan Jun Zhang

    Citation: Virology Journal 2019 16:129

    Content type: Case Report

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  6. Capsid (C) protein plays an important role in the replication of classical swine fever virus (CSFV). The ubiquitin proteasome system (UPS) involves in replication of many viruses via modulation of viral protei...

    Authors: Yuming Chen, Erpeng Zhu, Shuangqi Fan, Hongxing Ding, Shengming Ma, Mengjiao Zhu, Shaofeng Deng, Jinding Chen and Mingqiu Zhao

    Citation: Virology Journal 2019 16:127

    Content type: Research

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  7. Since the discovery of mimivirus, numerous giant viruses associated with free-living amoebae have been described. The genome of giant viruses can be more than 2.5 megabases, and virus particles can exceed the ...

    Authors: Graziele Oliveira, Bernard La Scola and Jônatas Abrahão

    Citation: Virology Journal 2019 16:126

    Content type: Review

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  8. Dengue is an important mosquito-borne disease. There is currently only one licensed vaccine for dengue prevention. The vaccine provides higher efficacy in pre-vaccination dengue-seropositive persons but a high...

    Authors: Chukiat Sirivichayakul, Kriengsak Limkittikul, Pornthep Chanthavanich, Sutee Yoksan, Anuttarasakdi Ratchatatat, Jacqueline Kyungah Lim, Watcharee Arunsodsai and Arunee Sabchareon

    Citation: Virology Journal 2019 16:125

    Content type: Research

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  9. Despite the high yearly prevalence of Influenza, the pathogenesis mechanism and involved genes have not been fully known. Finding the patterns and mapping the complex interactions between different genes help ...

    Authors: Mohadeseh Zarei Ghobadi, Sayed-Hamidreza Mozhgani, Mahdieh Farzanehpour and Farida Behzadian

    Citation: Virology Journal 2019 16:124

    Content type: Research

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  10. Conventional assays to titrate polioviruses usually test serial dilutions inoculated into replicate cell cultures to determine a 50% cytopathic endpoint, a process that is both time-consuming and laborious. Su...

    Authors: Hasmik Manukyan, Elvira Rodionova, Tatiana Zagorodnyaya, Tsai-Lien Lin, Konstantin Chumakov and Majid Laassri

    Citation: Virology Journal 2019 16:122

    Content type: Methodology

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  11. Porcine epidemic diarrhea virus (PEDV) has caused enormous economic losses to the global pig industry. Currently available PEDV vaccine strains have limited protective effects against PEDV variant strains.

    Authors: Yu Wu, Wei Li, Qingfeng Zhou, Qunhui Li, Zhichao Xu, Hanqin Shen and Feng Chen

    Citation: Virology Journal 2019 16:121

    Content type: Research

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  12. Tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) is a novel target and molecule in the negative regulation of immune homeostasis. The present study aimed to investigate the dynamic expression of TI...

    Authors: Yi Liu, Jia Jin, Jian Ji, Xi-Mei Gao and Yu-Chen Fan

    Citation: Virology Journal 2019 16:120

    Content type: Research

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  13. In 2017–2018, a new highly pathogenic H5N6 avian influenza virus (AIV) variant appeared in poultry and wild birds in Asian and European countries and caused multiple outbreaks. These variant strains are differ...

    Authors: Lin Liu, Ying Zhang, Pengfei Cui, Congcong Wang, Xianying Zeng, Guohua Deng and Xiurong Wang

    Citation: Virology Journal 2019 16:119

    Content type: Research

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  14. Mycoviruses were recently discovered in the white pine blister rust (WPBR) fungus Cronartium ribicola (J.C. Fisch.). Detection and characterization of their double stranded RNA (dsRNA) would facilitate understand...

    Authors: Jun-Jun Liu, Yu Xiang, Richard A. Sniezko, Anna W. Schoettle, Holly Williams and Arezoo Zamany

    Citation: Virology Journal 2019 16:118

    Content type: Research

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  15. Human Papilloma Virus (HPV) DNA tests are highly sensitive and can triage women with mild lesions, improving the prognosis and diagnosis of cervical lesions. However, additional efficient strategies should be ...

    Authors: Yuejie Li, Jie Liu, Li Gong, Xingwang Sun and Wenbo Long

    Citation: Virology Journal 2019 16:117

    Content type: Research

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  16. Finding new biomarkers for the early detection of cervical cancer is an essential requirement in this field. In this study, we aimed to evaluate the expression level of potential biomarkers in progression of c...

    Authors: Mahdieh Farzanehpour, Sayed-Hamidreza Mozhgani, Somayeh Jalilvand, Ebrahim Faghihloo, Setareh Akhavan, Vahid Salimi and Talat Mokhtari Azad

    Citation: Virology Journal 2019 16:116

    Content type: Research

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  17. Hepatitis B virus-related decompensated cirrhosis is difficult to cure but has a high readmission rate due to multiple complications. Our aim was to investigate the diagnostic potential value of plasma diamine...

    Authors: Feng-Cai Li, Yu-Chen Fan, Yue-Kai Li and Kai Wang

    Citation: Virology Journal 2019 16:115

    Content type: Research

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  18. Human papillomavirus type-6 (HPV6) is the major etiological agent of anogenital warts both men and women. The present study aimed to characterize the genetic diversity among HPV6 in Southwest China, and to inv...

    Authors: Zuyi Chen, Qiongyao Li, Jian Huang, Jin Li, Feng Yang, Xun Min and Zehui Chen

    Citation: Virology Journal 2019 16:114

    Content type: Research

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  19. Trichoderma spp. are used extensively in agriculture as biological control agents to prevent soil-borne plant diseases. In recent years, mycoviruses from fungi have attracted increasing attention due to their eff...

    Authors: Chenchen Liu, Mei Li, Estifanos Tsegaye Redda, Jie Mei, Jiantai Zhang, Beilei Wu and Xiliang Jiang

    Citation: Virology Journal 2019 16:113

    Content type: Research

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  20. Reverse genetics systems enable the manipulation of viral genomes and therefore serve as robust reverse genetic tools to study RNA viruses. A DNA-launched rescue system initiates the transcription of viral gen...

    Authors: Ruihua Zhang, Jingjing Lan, Haie Li, Junhao Chen, Yupeng Yang, Shaoli Lin, Zhijing Xie and Shijin Jiang

    Citation: Virology Journal 2019 16:112

    Content type: Research

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  21. Viral respiratory tract infections are common during early childhood. How they impact cystic fibrosis lung disease history in young children is poorly known. The principal aim o...

    Authors: Mathilde Eymery, Florence Morfin, Anne Doleans-Jordheim, Marie Perceval, Camille Ohlmann, Catherine Mainguy and Philippe Reix

    Citation: Virology Journal 2019 16:111

    Content type: Research

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  22. Iridoviruses are large DNA viruses that cause diseases in fish, amphibians and insects. Singapore grouper iridovirus (SGIV) is isolated from cultured grouper and characterized as a ranavirus. ICP46 is defined ...

    Authors: Li-Qun Xia, Jian-Lin Chen, Hong-Lian Zhang, Jia Cai, Sheng Zhou and Yi-Shan Lu

    Citation: Virology Journal 2019 16:110

    Content type: Research

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  23. The aim of this article is to summarise the virology content presented at the 9th Lorne Infection and Immunity Conference, Australia, in February 2019. The broad program included virology as a key theme, and t...

    Authors: Gregor Ebert, Prasad N. Paradkar and Sarah L. Londrigan

    Citation: Virology Journal 2019 16:109

    Content type: Meeting report

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  24. Bovine leukemia virus (BLV) causes enzootic bovine leucosis and is widely spread worldwide, except several European countries, Australia and New Zealand. Although BLV is highly prevalent in China, information ...

    Authors: Yi Yang, Lina Chen, Maoli Dong, Wenjiang Huang, Xiaoli Hao, Yalan Peng, Zaicheng Gong, Aijian Qin, Shaobin Shang and Zhangping Yang

    Citation: Virology Journal 2019 16:108

    Content type: Short report

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  25. The indicating FTA card is a dry medium used for collection of cervical samples. HPVIR is a multiplex real-time PCR test that detects 12 high-risk human papillomavirus types (hrHPV) and provides single genotyp...

    Authors: Inger Gustavsson, Riina Aarnio, Mattias Myrnäs, Julia Hedlund-Lindberg, Ongeziwe Taku, Tracy Meiring, Ingrid Wikström, Stefan Enroth, Anna-Lise Williamson, Matts Olovsson and Ulf Gyllensten

    Citation: Virology Journal 2019 16:107

    Content type: Research

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  26. Plant viruses can affect vector’s behaviors in order to enhance viral transmission. Cucurbit chlorotic yellows virus (CCYV) (genus Crinivirus) is an emergent RNA plant virus and is transmitted specifically by bio...

    Authors: Shaohua Lu, Mingshun Chen, Jingjing Li, Yan Shi, Qinsheng Gu and Fengming Yan

    Citation: Virology Journal 2019 16:106

    Content type: Research

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  27. The gut microbiome is closely associated with the health of the host; although the interaction between the bacterial microbiome and the whole virome has rarely been studied, it is likely of medical importance....

    Authors: Heng Li, Hongzhe Li, Jingjing Wang, Lei Guo, Haitao Fan, Huiwen Zheng, Zening Yang, Xing Huang, Manman Chu, Fengmei Yang, Zhanlong He, Nan Li, Jinxi Yang, Qiongwen Wu, Haijing Shi and Longding Liu

    Citation: Virology Journal 2019 16:105

    Content type: Research

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  28. The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence in C...

    Authors: Lem Edith Abongwa, Anthony Kebira Nyamache, Judith Ndongo Torimiro, Paul Okemo and Fokunang Charles

    Citation: Virology Journal 2019 16:103

    Content type: Research

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  29. Dengue virus (DENV) infection is one of the biggest challenges for human health in the world. In addition, a secondary DENV infection sometimes causes dengue hemorrhagic fever (DHF), which frequently leads to ...

    Authors: Keita Suzuki, Emi E. Nakayama, Akatsuki Saito, Akio Egawa, Tairyu Sato, Juthamas Phadungsombat, Rummana Rahim, Abu Hasan, Hisahiko Iwamoto, Mizanur Rahman and Tatsuo Shioda

    Citation: Virology Journal 2019 16:102

    Content type: Research

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  30. Current HCV treatments are genotype specific although potential pan-genotype treatments have recently been described. Therefore, genotyping is an essential tool for the therapeutic management of HCV infection ...

    Authors: Paul Alain Tagnouokam-Ngoupo, Marie Nicole Ngoufack, Sebastien Kenmoe, Simon Frédéric Lissock, Marie Amougou-Atsama, Robert Banai, Laure Ngono and Richard Njouom

    Citation: Virology Journal 2019 16:101

    Content type: Research

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  31. Recombinant Modified Vaccinia Virus Ankara has been employed as a safe and potent viral vector vaccine against infectious diseases and cancer. We generated recMVAs encoding norovirus GII.4 genotype capsid prot...

    Authors: Franziska Kugler, Ingo Drexler, Ulrike Protzer, Dieter Hoffmann and Hassan Moeini

    Citation: Virology Journal 2019 16:100

    Content type: Methodology

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  32. Coxsackievirus A10 (CA10) constitutes one of the four major pathogens causing hand, foot and mouth disease in infants. Infectious clones are of great importance for studying viral gene functions and pathogenic...

    Authors: Qiliang Liu, Hanliang Dan, Xiaoping Zhao, Huoying Chen, Yongbei Chen, Ning Zhang, Zhijing Mo and Hongbo Liu

    Citation: Virology Journal 2019 16:98

    Content type: Research

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  33. Transmissible gastroenteritis virus (TGEV), a member of the family Coronaviridae, causes lethal watery diarrhea in piglets. Previous studies have revealed that the coronaviruses develop various strategies to evad...

    Authors: Yanan Wang, Aoying Sun, Yu Sun, Sijia Zhang, Tian Xia, Tiantian Guo, Zhenye Hao, Li Sun, Yanping Jiang, Xinyuan Qiao, Wen Cui, Lijie Tang, Yigang Xu, Yijing Li and Li Wang

    Citation: Virology Journal 2019 16:97

    Content type: Research

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  34. Dengue fever is a febrile disease caused by dengue virus (DENV), which affects people throughout the tropical and subtropical regions of the world, including Indonesia. East Kalimantan (Borneo) province suffer...

    Authors: R. Tedjo Sasmono, Lily Pertiwi Kalalo, Suryani Trismiasih, Dionisius Denis, Benediktus Yohan, Rahma F. Hayati and Sotianingsih Haryanto

    Citation: Virology Journal 2019 16:93

    Content type: Research

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  35. HPV DNA Array is an E1-targeting PCR genotyping test, with capability of distinguishing 18 high-risk (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) and 11 low-risk HPV types (6, 11, 4...

    Authors: Aleksandra Pesic, Amrei Krings, Matthias Hempel, Rosemarie Preyer, Kimon Chatzistamatiou, Theodoros Agorastos and Andreas M. Kaufmann

    Citation: Virology Journal 2019 16:92

    Content type: Research

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  36. Influenza A and B viruses mainly cause respiratory infectious disease. Till now, few tests are able to simultaneously detect both, especially in primary medical establishments.

    Authors: Qingjun Pan, Weiquan Wu, Shuzhen Liao, Sijie Wang, Chunfei Zhao, Chen Li and Ping Wu

    Citation: Virology Journal 2019 16:91

    Content type: Research

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  37. Nelson Bay orthoreovirus (NBV) was first isolated over 40 years ago from a fruit bat in Australia. Normally, NBV does not cause human diseases, but recently several NBV strains have been associated with human ...

    Authors: Xiao-Li Tao, Wei Zhao, Wei Tong, Xiao-Fang Wang, Li-Li Dou, Jiang-Man Chen, Nian Liu, Ying Lu, Yi-Bo Zhang, Xu-Peng Jin, Yan-Fei Shen, Hong-Yan Zhao, Hong Jin and Yong-Gang Li

    Citation: Virology Journal 2019 16:90

    Content type: Research

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  38. A tenuivirus, referred to here as JKI 29327, was isolated from a black medic (Medicago lupulina) plant collected in Austria. The virus was mechanically transmitted to Nicotiana benthamiana, M. lupulina, M. sativa

    Authors: Yahya Z. A. Gaafar, Katja R. Richert-Pöggeler, Angelika Sieg-Müller, Petra Lüddecke, Kerstin Herz, Jonas Hartrick, Yvonne Seide, Heinrich-Josef Vetten and Heiko Ziebell

    Citation: Virology Journal 2019 16:89

    Content type: Short report

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  39. Human infection with avian influenza H7N9 virus was first reported in 2013. Since the fifth epidemic, a highly pathogenic avian influenza (HPAI) H7N9 virus has emerged and caused 33 human infections. Several p...

    Authors: Jing Tang, Jing Zhang, Jianfang Zhou, Wenfei Zhu, Lei Yang, Shumei Zou, Hejiang Wei, Li Xin, Weijuan Huang, Xiyan Li, Yanhui Cheng and Dayan Wang

    Citation: Virology Journal 2019 16:87

    Content type: Research

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  40. Human adenoviruses are a common group of viruses that cause acute infectious diseases. Human adenovirus (HAdV) 3 and HAdV 7 cause major outbreaks of severe pneumonia. A reliable and practical method for HAdV t...

    Authors: Rui-huan Wang, Hong Zhang, Yi Zhang, Xin-na Li, Xin-xin Shen, Ju-ju Qi, Guo-hao Fan, Xing-yu Xiang, Zhi-fei Zhan, Zi-wei Chen and Xue-jun Ma

    Citation: Virology Journal 2019 16:86

    Content type: Methodology

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  41. Type A influenza viruses (IAVs) cause significant infections in humans and multiple species of animals including pigs, horses, birds, dogs and some marine animals. They are of complicated phylogenetic diversit...

    Authors: Qingye Zhuang, Suchun Wang, Shuo Liu, Guangyu Hou, Jinping Li, Wenming Jiang, Kaicheng Wang, Cheng Peng, Dong Liu, Aizhen Guo and Jiming Chen

    Citation: Virology Journal 2019 16:85

    Content type: Research

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  42. Advances in molecular laboratory techniques are changing the prospects for the diagnosis of viral infectious diseases. Multiplex polymerase chain reaction assay (multiplex-PCR) can detect dozens of pathogens s...

    Authors: Le Wang, Shuo Yang, Xiaotong Yan, Teng Liu, Zhishan Feng and Guixia Li

    Citation: Virology Journal 2019 16:84

    Content type: Research

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