Emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) in North America, Asia and Europe has caused severe economic loss to the global swine industry. However, the virome of PEDV infected pigs an...
Authors: Qi Chen, Leyi Wang, Ying Zheng, Jianqiang Zhang, Baoqing Guo, Kyoung-Jin Yoon, Phillip C. Gauger, Karen M. Harmon, Rodger G. Main and Ganwu Li
Currently, the role of human papillomavirus (HPV)-58 in southwestern China has been unexplored. Although there is some controversy, it is proposed that the viral load of HPV correlates with the severity of int...
Authors: Wenbo Long, Zixi Yang, Xiabin Li, Ming Chen, Jie Liu, Yuanxue Zhang and Xingwang Sun
Grass carp (Ctenopharyngodon idella) hemorrhagic disease is caused by an acute infection with grass carp reovirus (GCRV). The frequent outbreaks of this disease have suppressed development of the grass carp farmi...
Authors: Hao Wang, Weisha Liu, Meng Sun, Dubo Chen, Lingbing Zeng, Liqun Lu and Jing Xie
Cucurbit chlorotic yellows virus (CCYV), a bipartite crinivirus, causes chlorotic leaf spots and yellowing symptoms on cucurbit leaves. We previously developed an infectious clone of CCYV. Limited work has been c...
Authors: Ying Wei, Xiaoyu Han, Zhenyue Wang, Qinsheng Gu, Honglian Li, Linlin Chen, Bingjian Sun and Yan Shi
Human metapneumovirus (HMPV) is established as one of the causative agents of respiratory tract infections. To date, there are limited reports that describe the effect of HMPV genotypes and/or viral load on di...
Authors: Xiang Yong Oong, Jack Bee Chook, Kim Tien Ng, Wei Zhen Chow, Kok Gan Chan, Nik Sherina Hanafi, Yong Kek Pang, Yoke Fun Chan, Adeeba Kamarulzaman and Kok Keng Tee
Maize lethal necrosis is caused by a synergistic co-infection of Maize chlorotic mottle virus (MCMV) and a specific member of the Potyviridae, such as Sugarcane mosaic virus (SCMV), Wheat streak mosaic virus (WSM...
Authors: Mwathi Jane Wamaitha, Deepti Nigam, Solomon Maina, Francesca Stomeo, Anne Wangai, Joyce Njoki Njuguna, Timothy A. Holton, Bramwel W. Wanjala, Mark Wamalwa, Tanui Lucas, Appolinaire Djikeng and Hernan Garcia-Ruiz
Artemisia scoparia Waldst and Kit is a famous traditional Chinese medicine widely distributed in Xinjiang, China. Flavonoids extracted from it exhibits inhibitory activities against several influenza virus strain...
Authors: Haiyan Yan, Huiqiang Wang, Linlin Ma, Xueping Ma, Jinqiu Yin, Shuo Wu, Hua Huang and Yuhuan Li
Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, causing a major risk of liver disease and hepatocellular carcinoma (HCC). Many mouse models have been tried to establish ...
Authors: Xian Wang, Jianmin Zhu, Yong Zhang, Yue Li, Tai Ma, Qun Li, Jiegou Xu and Long Xu
N6-methyl-adenosine (m6A) is a prevalent RNA modification in many species. Abnormal m6A methylation levels can lead to RNA dysfunction and can cause diseases. Tobacco mosai...
Authors: Zhurui Li, Jing Shi, Lu Yu, Xiaozhen Zhao, Longlu Ran, Deyu Hu and Baoan Song
Hepatocytes infected by hepatitis B virus (HBV) produce different HBV RNA species, including pregenomic RNA (pgRNA), which is reverse transcribed during replication. Particles containing HBV RNA are present in...
Authors: Kasthuri Prakash, Gustaf E. Rydell, Simon B. Larsson, Maria Andersson, Gunnar Norkrans, Heléne Norder and Magnus Lindh
‘Rapid Apple Decline’ (RAD) is a newly emerging problem of young, dwarf apple trees in the Northeastern USA. The affected trees show trunk necrosis, cracking and canker before collapse in summer. In this study...
Authors: Huawei Liu, Liping Wu, Ekaterina Nikolaeva, Kari Peter, Zongrang Liu, Dimitre Mollov, Mengji Cao and Ruhui Li
Chikungunya virus (CHIKV) and dengue virus (DENV) are arboviruses that share the same Aedes mosquito vector, and there is much overlap in endemic areas. In India, co-infection with both viruses is often reported....
Adverse drug reactions (ADRs) are a significant problem for HIV patients, with the risk of developing ADRs increasing as the infection progresses to AIDS. However, the pathophysiology underlying ADRs remains u...
Authors: Kemi Adeyanju, John R. Bend, Michael J. Rieder and Gregory A. Dekaban
Hantavirus infection is a zoonotic disease that is associated with hemorrhagic fever with renal syndrome and cardiopulmonary syndrome in human. Anjozorobe virus, a representative virus of Thailand orthohantavi...
The human T-lymphotropic virus type 1 (HTLV-1) affects 2–5 million people worldwide, and is associated with a number of degenerative and infectious diseases. The Envelope glycoproteins (gp) are highly conserve...
Authors: Maria de Nazaré do Socorro de Almeida Viana, Akim Felipe Santos Nobre, Edivaldo Costa Jr, Ingrid Christiane Silva, Bruna Teles Pinheiro, Cássia Cristine Costa Pereira, Louise de Souza Canto Ferreira, Danilo Souza de Almeida, Marcos William Leão de Araújo, Mariza da Silva Borges, Carlos Araujo da Costa, Edna Aoba Yassui Ishikawa, Stephen Francis Ferrari and Maísa Silva de Sousa
Human adenovirus (HAdV) serotypes 2, 3 and 7 are more prevalent than other serotypes and have been associated with severe pneumonia in pediatric children. Molecular typing of HAdV is not routinely performed in...
Authors: Fang-zhou Qiu, Xin-xin Shen, Meng-chuan Zhao, Li Zhao, Su-xia Duan, Chen Chen, Ju-Ju Qi, Gui-xia Li, Le Wang, Zhi-shan Feng and Xue-jun Ma
The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs).
Authors: Mary Bridget Nanteza, Barnabas Bakamutumaho, Annet Kisakye, Prossy Namuwulya, Henry Bukenya, Edson Katushabe, Josephine Bwogi, Charles Rutebarika Byabamazima, Raffaella Williams and Nicksy Gumede
Zika virus infection in new born is linked to congenital syndromes, especially microcephaly. Studies have shown that these neuropathies are the result of significant death of neuronal progenitor cells in the c...
Authors: Julie Gaburro, Asim Bhatti, Vinod Sundaramoorthy, Megan Dearnley, Diane Green, Saeid Nahavandi, Prasad N. Paradkar and Jean-Bernard Duchemin
Rotavirus infection is the most common cause of severe gastroenteritis in children under five years of age in both developed and developing countries. The World Health Organisation (WHO) recommends the surveil...
Authors: Catherine Boni-cisse, Sindou Meite, Alice Britoh Mlan, Flore Zaba, Rebecca N’Guessan, Nicaise Aka Lepri and Bélinda Lartey
Variations in HPV LCR/E6/E7 have been shown to be associated with the viral persistence and cervical cancer development. So far, there are few reports about the polymorphisms of the HPV-58 LCR/E6/E7 sequences ...
Authors: Juemin Xi, Junying Chen, Miaoling Xu, Hongying Yang, Songjiao Wen, Yue Pan, Xiaodan Wang, Chao Ye, Lijuan Qiu and Qiangming Sun
To investigate the predictive capability of microRNAs (miRNAs) prior treatment for HBsAg clearance in chronic hepatitis B (CHB) treated with pegylated interferon α-2a (PEG-IFNα-2a).
Authors: Yanlin Yang, Ming Liu, Ying Deng, Yan Guo, Xuqing Zhang, Dedong Xiang, Li Jiang, Zhonglan You, Yi Wu, Maoshi Li and Qing Mao
The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six...
Authors: Ameh S. James, Shawn Todd, Nina M. Pollak, Glenn A. Marsh and Joanne Macdonald
Infection with Parvovirus B19 (B19V), Cytomegalovirus (CMV) and Herpes Simplex Virus-1/2 (HSV-1/2) may cause fetal loses including spontaneous abortion, intrauterine fetal death and non-immune hydrops fetalis....
Authors: Ya-Ling Gao, Zhan Gao, Miao He and Pu Liao
In China, the rice pathogen Rice yellow stunt virus (RYSV), a member of the genus Nucleorhabdovirus in the family Rhabdoviridae, was a severe threat to rice production during the1960s and1970s. Fundamental aspect...
Authors: Haitao Wang, Juan Wang, Yunjie Xie, Zhijun Fu, Taiyun Wei and Xiao-Feng Zhang
Mosquitoes are the potential vectors for a variety of viruses that can cause diseases in the human and animal populations. Viruses in the order Picornavirales infect a broad range of hosts, including mosquitoes. ...
Authors: Harindranath Cholleti, Juliette Hayer, Jose Fafetine, Mikael Berg and Anne-Lie Blomström
