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Clinical Virology

Section Editor: Fred Kibenge, University of Prince Edward Island, Canada
Deputy Section Editor: Kin On Kwok, The Chinese University of Hong Kong 

The Clinical Virology section of the Virology Journal covers the clinical aspects of pathogenic viruses in individual hosts and populations of humans, animals, or plants. This includes the study of viral diseases, laboratory diagnosis, treatment (antiviral therapies), and control (biocontainment and vaccines) using classical, molecular, or immunological methods. Studies, including the virome, virus-host interactions, and epidemiology of viral infections, are encouraged.

  1. Maintaining adequate drug adherence is crucial to ensure the HIV prevention benefits of pre-exposure prophylaxis (PrEP). We developed an enzymatic assay for rapidly measuring tenofovir-diphosphate (TFV-DP) con...

    Authors: Ayokunle O. Olanrewaju, Benjamin P. Sullivan, Ashley R. Bardon, Tiffany J. Lo, Tim R. Cressey, Jonathan D. Posner and Paul K. Drain

    Citation: Virology Journal 2021 18:77

    Content type: Short report

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  2. We stratified post-COVID patients into four newly established clinical groups based on the presence or absence of at least one subjective respiratory symptom and at least one objective sign of pulmonary involv...

    Authors: Mikulas Skala, Michal Svoboda, Michal Kopecky, Eva Kocova, Martin Hyrsl, Michal Homolac, Viktor Chrobok, Pavel Bostik, Miroslav Fajfr, Petr Prasil, Stanislav Plisek, Radek Sleha and Vladimir Koblizek

    Citation: Virology Journal 2021 18:73

    Content type: Short report

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  3. Risk scores are needed to predict the risk of death in severe coronavirus disease 2019 (COVID-19) patients in the context of rapid disease progression.

    Authors: Xiude Fan, Bin Zhu, Masoud Nouri-Vaskeh, Chunguo Jiang, Xiaokai Feng, Kyle Poulsen, Behzad Baradaran, Jiansong Fang, Erfan Ahmadi Ade, Akbar Sharifi, Zhigang Zhao, Qunying Han, Yong Zhang, Liming Zhang and Zhengwen Liu

    Citation: Virology Journal 2021 18:67

    Content type: Research

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  4. The sample collection procedure for SARS-CoV-2 has a strong impact on diagnostic capability, contact tracing approach, ultimately affecting the infection containment performance. This study demonstrates that s...

    Authors: Silvia Ricci, Lorenzo Lodi, Francesco Citera, Francesco Nieddu, Maria Moriondo, Valentina Guarnieri, Mattia Giovannini, Giuseppe Indolfi, Massimo Resti, Alberto Zanobini and Chiara Azzari

    Citation: Virology Journal 2021 18:59

    Content type: Short report

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  5. With the novel coronavirus pandemic, the impact on the healthcare system and workers cannot be overlooked. However, studies on the infection status of medical personnel are still lacking. It is imperative to e...

    Authors: Golnar Sabetian, Mohsen Moghadami, Leila Hashemizadeh Fard Haghighi, Reza Shahriarirad, Mohammad Javad Fallahi, Naeimehossadat Asmarian and Yalda Sadat Moeini

    Citation: Virology Journal 2021 18:58

    Content type: Research

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  6. The coronavirus disease 2019 (COVID-19) pandemic remains ongoing around the world, including in areas where dengue is endemic. Dengue and COVID-19, to some extent, have similar clinical and laboratory features...

    Authors: Marsha S. Santoso, Sri Masyeni, Sotianingsih Haryanto, Benediktus Yohan, Martin L. Hibberd and R. Tedjo Sasmono

    Citation: Virology Journal 2021 18:54

    Content type: Short report

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  7. The sudden arrival of the COVID-19 pandemic placed significant stresses on supply chains including viral transport medium (VTM). The VTM that was urgently required needed to support viral replication, as well ...

    Authors: Julie McAuley, Claire Fraser, Elena Paraskeva, Elizabeth Trajcevska, Michelle Sait, Nancy Wang, Eric Bert, Damian Purcell and Richard Strugnell

    Citation: Virology Journal 2021 18:53

    Content type: Short report

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  8. To investigate the predictive significance of different pneumonia scoring systems in clinical severity and mortality risk of patients with severe novel coronavirus pneumonia.

    Authors: PengFei Cheng, Hao Wu, JunZhe Yang, XiaoYang Song, MengDa Xu, BiXi Li, JunJun Zhang, MingZhe Qin, Cheng Zhou and Xiang Zhou

    Citation: Virology Journal 2021 18:33

    Content type: Research

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  9. Despite being a leading infectious cause of childhood disability globally, testing for cytomegalovirus (CMV) infections in pregnancy is generally not done in Sub-Sahara Africa (SSA), where breastfeeding practi...

    Authors: Kerina Duri, Simbarashe Chimhuya, Exnevia Gomo, Privilege Tendai Munjoma, Panashe Chandiwana, Louis Marie Yindom, Kudakwashe Mhandire, Asaph Ziruma, Sekesai Mtapuri-Zinyowera, Lovemore Ronald Mazengera, Benjamin Misselwitz, Felicity Zvanyadza Gumbo, Sebastian Jordi and Sarah Rowland-Jones

    Citation: Virology Journal 2021 18:30

    Content type: Research

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  10. Diverse vaccination outcomes and protection levels among different populations pose a serious challenge to the development of an effective malaria vaccine. Co-infections are among many factors associated with ...

    Authors: Anneth-Mwasi Tumbo, Tobias Schindler, Jean-Pierre Dangy, Nina Orlova-Fink, Jose Raso Bieri, Maximillian Mpina, Florence A. Milando, Omar Juma, Ali Hamad, Elizabeth Nyakarungu, Mwajuma Chemba, Ali Mtoro, Kamaka Ramadhan, Ally Olotu, Damas Makweba, Stephen Mgaya…

    Citation: Virology Journal 2021 18:28

    Content type: Research

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  11. COVID-19 is diagnosed via detection of SARS-CoV-2 RNA using real time reverse-transcriptase polymerase chain reaction (rtRT-PCR). Performance of many SARS-CoV-2 rtRT-PCR assays is not entirely known due to the...

    Authors: Jamil N. Kanji, Nathan Zelyas, Clayton MacDonald, Kanti Pabbaraju, Muhammad Naeem Khan, Abhaya Prasad, Jia Hu, Mathew Diggle, Byron M. Berenger and Graham Tipples

    Citation: Virology Journal 2021 18:13

    Content type: Short report

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  12. Chemokine levels in severe coronavirus disease 2019 (COVID-19) patients have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 has not yet been established. According to the epide...

    Authors: Xueyan Xi, Yang Guo, Min Zhu, Yuhui Wei, Gang Li, Boyu Du and Yunfu Wang

    Citation: Virology Journal 2021 18:12

    Content type: Research

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  13. The fight against the COVID-19 pandemic has created an urgent need to rapidly detect infected people. The challenge for clinical laboratories has been finding a high throughput, cost-efficient, and accurate te...

    Authors: Wesley Freppel, Natacha Merindol, Fabien Rallu and Marco Bergevin

    Citation: Virology Journal 2020 17:196

    Content type: Methodology

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  14. The new emerging coronavirus disease 2019 (COVID-19) overall shares similar symptoms with other common respiratory viral infections. We aimed in this study to compare COVID-19 and human adenovirus (HAdV) infec...

    Authors: Kuanrong Li, Ling Li, Xianfeng Wang, Hui Li, Jun Chen, Lei Liu, Jianbo Shao, Yi Xu, Liya He, Sitang Gong, Huimin Xia and Huiying Liang

    Citation: Virology Journal 2020 17:193

    Content type: Research

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  15. Several molecular kits are available for SARS-CoV-2 diagnosis, mostly lacking of proper clinical evaluation due to the emergency caused by COVID19 pandemia, particularly at developing countries like Ecuador.

    Authors: Byron Freire-Paspuel and Miguel Angel Garcia-Bereguiain

    Citation: Virology Journal 2020 17:178

    Content type: Short report

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    The Correction to this article has been published in Virology Journal 2021 18:41

  16. There is plenitude of information on HIV infection among pregnant mothers attending antenatal care (ANC) in sub-Saharan Africa. However, the epidemiology of HBV–HIV co-infections in the same cohort is not clea...

    Authors: Hussein Mukasa Kafeero, Dorothy Ndagire, Ponsiano Ocama, Abdul Walusansa and Hakim Sendagire

    Citation: Virology Journal 2020 17:170

    Content type: Research

    Published on:

  17. Human Papillomavirus (HPV) infection is one of the most important causes of cancer. It can play a role in cervical and extra-cervical cancers. Penile cancer is rare, even if an increasing trend was recently re...

    Authors: Narcisa Muresu, Giovanni Sotgiu, Laura Saderi, Illari Sechi, Antonio Cossu, Vincenzo Marras, Marta Meloni, Marianna Martinelli, Clementina Cocuzza, Francesco Tanda and Andrea Piana

    Citation: Virology Journal 2020 17:161

    Content type: Short report

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  18. Fast, reliable and easy to handle methods are required to facilitate urgently needed point-of-care testing (POCT) in the current coronavirus pandemic. Life-threatening severe acute respiratory syndrome coronav...

    Authors: Lena Mautner, Christin-Kirsty Baillie, Heike Marie Herold, Wolfram Volkwein, Patrick Guertler, Ute Eberle, Nikolaus Ackermann, Andreas Sing, Melanie Pavlovic, Ottmar Goerlich, Ulrich Busch, Lars Wassill, Ingrid Huber and Armin Baiker

    Citation: Virology Journal 2020 17:160

    Content type: Methodology

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