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Virology Journal

Hepatitis viruses

Section Editor: Alan McLachlan, University of Illinois at Chicago, USA 
Deputy Section Editor: Susan Uprichard, University of Illinois at Chicago, USA 

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  1. Content type: Research

    An association between hepatitis C virus (HCV) and type 2 diabetes (T2D) is supported by numerous epidemiologic studies. We hypothesized that HCV could infect human pancreatic islet cells in vitro.

    Authors: Jason T. Blackard, Ling Kong, Angela Lombardi, Dirk Homann, Sara Salehi Hammerstad and Yaron Tomer

    Citation: Virology Journal 2017 14:237

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  2. Content type: Research

    It has been widely accepted that hepatitis B virus X protein (HBx) plays an important role in hepatocellular carcinoma (HCC). This study aimed to explore the function of long non-coding RNAs (lncRNAs) in the e...

    Authors: Yinji Jin, Di Wu, Weiwei Yang, Mingjiao Weng, Yafei Li, Xuefei Wang, Xiao Zhang, Xiaoming Jin and Tianzhen Wang

    Citation: Virology Journal 2017 14:238

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  3. Content type: Research

    Direct acting antivirals (DAAs) provide efficient hepatitis C virus (HCV) therapy and clearance for a majority of patients, but are not available or effective for all patients. They risk developing HCV-induced...

    Authors: Sara M. Ø. Solbak, Eldar Abdurakhmanov, Anni Vedeler and U. Helena Danielson

    Citation: Virology Journal 2017 14:236

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  4. Content type: Research

    Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationshi...

    Authors: Peng Huang, Haozhi Fan, Ting Tian, Peiwen Liao, Jun Li, Rongbin Yu, Xueshan Xia, Yue Feng, Jie Wang, Yuan Liu, Yun Zhang and Ming Yue

    Citation: Virology Journal 2017 14:235

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  5. Content type: Research

    Infection with the hepatitis E virus (HEV) can cause acute hepatitis in endemic areas in immune-competent hosts, as well as chronic infection in immune-compromised subjects in non-endemic areas. Most studies a...

    Authors: Ananta Shrestha, Anurag Adhikari, Manjula Bhattarai, Ramanuj Rauniyar, Jose D. Debes, André Boonstra, Thupten K. Lama, Mamun Al Mahtab, Amna Subhan Butt, Sheikh Mohammad Fazle Akbar, Nirmal Aryal, Sapana Karn, Krishna Das Manandhar and Birendra Prasad Gupta

    Citation: Virology Journal 2017 14:228

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  6. Content type: Research

    Hepatitis C virus (HCV) genotypes and subtypes are considered an important tool for epidemiological and clinical studies and valuable markers for disease progression and response to antiviral therapy. The aim ...

    Authors: Amen Bawazir, Fahad AlGusheri, Hoda Jradi, Mohammed AlBalwi and Abdel-Galil Abdel-Gader

    Citation: Virology Journal 2017 14:208

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  7. Content type: Research

    Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-H...

    Authors: Lei Li, Sheng Li, Yun Zhou, Lu Yang, Di Zhou, Yan Yang, Mengji Lu, Dongliang Yang and Jingjiao Song

    Citation: Virology Journal 2017 14:205

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  8. Content type: Research

    The pathogenesis of acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB) is not well understood. The aim of this study was to investigate whether there is an association between HBV polymerase (P...

    Authors: Shan Gao, Shivali S. Joshi, Carla Osiowy, Y. Chen, Carla S. Coffin and Z-P. Duan

    Citation: Virology Journal 2017 14:203

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  9. Content type: Research

    Occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the serum and/or liver in HBsAg-negative individuals. OBI is associated with the risk of viral transmission, espe...

    Authors: Yan Mardian, Yoshihiko Yano, Widya Wasityastuti, Neneng Ratnasari, Yujiao Liang, Wahyu Aristyaning Putri, Teguh Triyono and Yoshitake Hayashi

    Citation: Virology Journal 2017 14:201

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  10. Content type: Research

    Seroprevalence of hepatitis C in Khyber Pakhtunkhwa province of Pakistan was determined by screening blood samples of expectant mothers seeking antenatal care in gynecological units of district hospitals. The ...

    Authors: Zobia Afsheen, Bashir Ahmad and Shumaila Bashir

    Citation: Virology Journal 2017 14:195

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  11. Content type: Research

    Hepatitis B virus (HBV) infection is a serious public health problem leading to cirrhosis and hepatocellular carcinoma. As the clinical utility of current therapies is limited, the development of new therapeut...

    Authors: Huifang Li, Junru Li, Yuan Tang, Lin Lin, Zhanglian Xie, Jia Zhou, Liyun Zhang, Xiaoyong Zhang, Xiaoshan Zhao, Zhengliang Chen and Daming Zuo

    Citation: Virology Journal 2017 14:178

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  12. Content type: Review

    There are an estimated 400 million chronic carriers of HBV worldwide; between 15 and 20 million have serological evidence of exposure to HDV. Traditionally, regions with high rates of endemicity are central an...

    Authors: Luan Felipo Botelho-Souza, Mariana Pinheiro Alves Vasconcelos, Alcione de Oliveira dos Santos, Juan Miguel Villalobos Salcedo and Deusilene Souza Vieira

    Citation: Virology Journal 2017 14:177

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  13. Content type: Research

    Direct-acting antivirals (DAAs) for chronic hepatitis C (CHC) treatment are tolerable and highly effective in a shorter period of time than before. However, resistance-associated variants (RAVs) can affect the...

    Authors: Jung Hwan Yu, Jung Il Lee, Kwan Sik Lee and Ja Kyung Kim

    Citation: Virology Journal 2017 14:164

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  14. Content type: Research

    Hepatitis C virus (HCV) is a leading cause of chronic liver disease and frequently progresses towards liver cirrhosis and Hepatocellular Carcinoma (HCC). This study aimed to determine the prevalence of HCV gen...

    Authors: Nausheen Nazir, Muhammad Rasul Jan, Amjad Ali, Muhammad Asif, Muhammad Idrees, Mohammad Nisar, Muhammad Zahoor and Naser M. Abd El-Salam

    Citation: Virology Journal 2017 14:160

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  15. Content type: Research

    The existing literature about HCV association with, and replication in mosquitoes is extremely poor. To fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of HCV E1E2 glyco...

    Authors: Catherine Fallecker, Alban Caporossi, Yassine Rechoum, Frederic Garzoni, Sylvie Larrat, Olivier François, Pascal Fender, Patrice Morand, Imre Berger, Marie-Anne Petit and Emmanuel Drouet

    Citation: Virology Journal 2017 14:161

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  16. Content type: Research

    Chronic hepatitis B virus (HBV) infection remains an important public health issue. A20, a ubiquitin-editing protein encoded by tumor necrosis factor alpha-inducible protein 3 (TNFAIP3) gene, is complicated in HB...

    Authors: Na Li, Ying Shi, Pingping Zhang, Jiao Sang, Fang Li, Huan Deng, Yi Lv, Qunying Han and Zhengwen Liu

    Citation: Virology Journal 2017 14:148

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  17. Content type: Research

    Because of shared modes of transmission, patients with hepatitis C virus (HCV) infection are often co-infected with other types of hepatitis viruses and/or HIV. We studied HCV viral load and its genotype patte...

    Authors: Marzieh Jamalidoust, Mandana Namayandeh, Mohsen Moghadami and Mazyar Ziyaeyan

    Citation: Virology Journal 2017 14:127

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  18. Content type: Case report

    The major resistance-associated substitution for sofosbuvir (S282T) in HCV NS5B causes severe viral fitness costs and rapidly reverts back to prototype in the absence of selection pressure. Accordingly, resist...

    Authors: Andreas Walker, Sandra Filke, Nadine Lübke, Martin Obermeier, Rolf Kaiser, Dieter Häussinger, Jörg Timm and Hans H. Bock

    Citation: Virology Journal 2017 14:106

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  19. Content type: Research

    In study TMC647055HPC2001, a 3-direct-acting-antiviral (DAA) regimen combining NS3/4A protease inhibitor simeprevir (SMV), non-nucleoside NS5B inhibitor TMC647055/ritonavir (RTV) and NS5A inhibitor JNJ-5691484...

    Authors: Leen Vijgen, Kim Thys, An Vandebosch, Pieter Van Remoortere, René Verloes and Sandra De Meyer

    Citation: Virology Journal 2017 14:101

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