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Influenza viruses

Section Editor: Hualan Chen, Chinese Academy of Agricultural Sciences, China 
Deputy Section Editor: Chengjun Li, Chinese Academy of Agricultural Sciences, China

The Influenza viruses section of Virology Journal will publish articles on all aspects of influenza virus research, including molecular genetics, molecular biology, biochemistry, biophysics, structural biology, cell biology, immunology, morphology, and pathogenesis. The section will also welcome the case reports of influenza outbreaks in both human and animal populations, and development and evaluation of vaccines and antiviral compounds in humans and animals.​​​​​​​

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  1. Content type: Research

    With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats and report on high frequency of avian H9 seroconversion in a species of free ranging bats, an important issue to address is the ...

    Authors: Tessa Slater, Isabella Eckerle and Kin-Chow Chang

    Citation: Virology Journal 2018 15:68

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  2. Content type: Research

    Non-structural protein NS1 of influenza A viruses harbours several determinants of pathogenicity and host-range. However it is still unclear to what extent each of its two structured domains (i.e. RNA-binding ...

    Authors: Sascha Trapp, Denis Soubieux, Alexandra Lidove, Evelyne Esnault, Adrien Lion, Vanaique Guillory, Alan Wacquiez, Emmanuel Kut, Pascale Quéré, Thibaut Larcher, Mireille Ledevin, Virginie Nadan, Christelle Camus-Bouclainville and Daniel Marc

    Citation: Virology Journal 2018 15:55

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  3. Content type: Research

    The influenza A virus non-structural protein 1 (NS1) is a multifunctional protein that plays an important role in virus replication, virulence and inhibition of the host antiviral immune response. In the avian...

    Authors: Jinghua Cheng, Chunling Zhang, Jie Tao, Benqiang Li, Ying Shi and Huili Liu

    Citation: Virology Journal 2018 15:57

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  4. Content type: Research

    The highly pathogenic avian influenza viruses of the H5 subtype, such as the H5N1 viral strains or the novel H5N8 and H5N2 reassortants, are of both veterinary and public health concern worldwide. To combat th...

    Authors: Violetta Sączyńska, Anna Bierczyńska-Krzysik, Violetta Cecuda-Adamczewska, Piotr Baran, Anna Porębska, Katarzyna Florys, Marcin Zieliński and Grażyna Płucienniczak

    Citation: Virology Journal 2018 15:13

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  5. Content type: Methodology

    Swine influenza is a respiratory infection of pigs that may have a significant economic impact in affected herds and pose a threat to the human population since swine influenza A viruses (swIAVs) are zoonotic ...

    Authors: Emilie Bonin, Stéphane Quéguiner, Cédric Woudstra, Stéphane Gorin, Nicolas Barbier, Timm C. Harder, Patrick Fach, Séverine Hervé and Gaëlle Simon

    Citation: Virology Journal 2018 15:7

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  6. Content type: Research

    Influenza is a severe contagious disease especially in children, elderly and immunocompromised patients. Beside vaccination, the discovery of new anti-viral agents represents an important strategy to encounter...

    Authors: Raihan Shah Mahmud, Ahmed Mostafa, Christin Müller, Pumaree Kanrai, Vera Ulyanova, Yulia Sokurenko, Julia Dzieciolowski, Irina Kuznetsova, Olga Ilinskaya and Stephan Pleschka

    Citation: Virology Journal 2018 15:5

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  7. Content type: Research

    Numerous toxicological studies have focused on injury caused by exposure to single types of nanoparticles, but few have investigated how such exposures impact a host’s immune response to pathogen challenge. Fe...

    Authors: Hao Chen, Xiao Zheng, Justine Nicholas, Sara T. Humes, Julia C. Loeb, Sarah E. Robinson, Joseph H. Bisesi Jr, Dipesh Das, Navid B. Saleh, William L. Castleman, John A. Lednicky and Tara Sabo-Attwood

    Citation: Virology Journal 2017 14:242

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  8. Content type: Research

    IFITM3 has been suggested to be associated with infection in some ethnic groups. Diabetes and hypercholesterolemia are also important clinical conditions that can predispose individual...

    Authors: Parvaneh Mehrbod, Sana Eybpoosh, Fatemeh Fotouhi, Hadiseh Shokouhi Targhi, Vahideh Mazaheri and Behrokh Farahmand

    Citation: Virology Journal 2017 14:218

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  9. Content type: Research

    Endothelial cells are believed to play an important role in response to virus infection. Our previous microarray analysis showed that H9N2 virus infection and inactivated viral particle inoculation increased t...

    Authors: Bo Feng, Lihong Zhao, Wei Wang, Jianfang Wang, Hongyan Wang, Huiqin Duan, Jianjun Zhang and Jian Qiao

    Citation: Virology Journal 2017 14:213

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  10. Content type: Research

    Since the highly pathogenic H5N1 influenza caused thousands of deaths of wild bird in this area in 2005, Qinghai Lake in China has become a hot spot for study of the influence of avian influenza to migratory w...

    Authors: Jie Dong, Hong Bo, Ye Zhang, Libo Dong, Shumei Zou, Weijuan Huang, Jia Liu, Dayan Wang and Yuelong Shu

    Citation: Virology Journal 2017 14:180

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  11. Content type: Research

    Cationic derivatives of polyprenols (trimethylpolyprenylammonium iodides – PTAI) with variable chain length between 6 and 15 isoprene units prepared from naturally occurring poly-cis-prenols were tested as DNA va...

    Authors: Anna Stachyra, Monika Rak, Patrycja Redkiewicz, Zbigniew Madeja, Katarzyna Gawarecka, Tadeusz Chojnacki, Ewa Świeżewska, Marek Masnyk, Marek Chmielewski, Agnieszka Sirko and Anna Góra-Sochacka

    Citation: Virology Journal 2017 14:168

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  12. Content type: Short Report

    Influenza A virus (IAV) PB1-F2 protein has been linked to viral virulence. Strains of the H3N2 subtype historically express full-length PB1-F2 proteins but during the 2010–2011 influenza seasons, nearly half o...

    Authors: Julie McAuley, Yi-Mo Deng, Brad Gilbertson, Charley Mackenzie-Kludas, Ian Barr and Lorena Brown

    Citation: Virology Journal 2017 14:162

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  13. Content type: Research

    Defective interfering (DI) viruses are natural antivirals made by nearly all viruses. They have a highly deleted genome (thus being non-infectious) and interfere with the replication of genetically related inf...

    Authors: Bo Meng, Kirsten Bentley, Anthony C. Marriott, Paul D. Scott, Nigel J. Dimmock and Andrew J. Easton

    Citation: Virology Journal 2017 14:138

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  14. Content type: Short report

    Low pathogenic avian influenza viruses (LPAIV) of the subtypes H5 and H7 are known to give rise to highly pathogenic (HP) phenotypes by spontaneous insertional mutations which convert a monobasic trypsin-sensi...

    Authors: Annika Graaf, Martin Beer and Timm Harder

    Citation: Virology Journal 2017 14:137

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  15. Content type: Research

    Recently, avian influenza virus has caused repeated worldwide outbreaks in humans. Live Poultry Markets (LPMs) play an important role in the circulation and reassortment of novel Avian Influenza Virus (AIVs). ...

    Authors: Xiaoxu Zeng, Mingbin Liu, Heng Zhang, Jingwen Wu, Xiang Zhao, Wenbing Chen, Lei Yang, Fenglan He, Guoyin Fan, Dayan Wang, Haiying Chen and Yuelong Shu

    Citation: Virology Journal 2017 14:136

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  16. Content type: Research

    Yearly influenza virus mutations potentially affect the performance of molecular assays, if nucleic acid changes involve the sequences in the assay. Because individual patient viral loads depend on variables s...

    Authors: Kenneth H. Rand, Maura Pieretti, Rodney Arcenas, Stacy G. Beal, Herbert Houck, Emma Boslet and John A. Lednicky

    Citation: Virology Journal 2017 14:128

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  17. Content type: Research

    Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group. Vaccination o...

    Authors: Joan E. M. van der Lubbe, Jessica Vreugdenhil, Sarra Damman, Joost Vaneman, Jaco Klap, Jaap Goudsmit, Katarina Radošević and Ramon Roozendaal

    Citation: Virology Journal 2017 14:123

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  18. Content type: Short Report

    Influenza virus isolation in embryonated chicken eggs (ECEs) is not applicable for rapid diagnosis, however it allows the recovery and propagation of the viable virus. A low number of infectious virus particle...

    Authors: Ilona Marcelina Gora, Malgorzata Kwasnik, Jan Franciszek Zmudzinski and Wojciech Rozek

    Citation: Virology Journal 2017 14:120

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  19. Content type: Short report

    On November 20, 2016 two novel strains of H5N6 highly pathogenic avian influenza virus (HPAIVs) were isolated from three whooper swans (Cygnus cygnus) at Gangjin Bay in South Jeolla province, South Korea. Identif...

    Authors: Jipseol Jeong, Chanjin Woo, Hon S. Ip, Injung An, Youngsik Kim, Kwanghee Lee, Seong-Deok Jo, Kidong Son, Saemi Lee, Jae-Ku Oem, Seung-Jun Wang, Yongkwan Kim, Jeonghwa Shin, Jonathan Sleeman and Weonhwa Jheong

    Citation: Virology Journal 2017 14:60

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