Retroviruses

Section Editor: Li Wu, Ohio State University, USA 
Deputy Section Editor: Ben Berkhout, University of Amsterdam, Netherlands ​​​​​​​

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  1. Research

    Putative progressive and abortive feline leukemia virus infection outcomes in captive jaguarundis (Puma yagouaroundi)

    Feline leukemia virus (FeLV) is an exogenous gammaretrovirus of domestic cats (Felis catus) and some wild felids. The outcomes of FeLV infection in domestic cats vary according to host susceptibility, virus strai...

    Claudia Filoni, A. Katrin Helfer-Hungerbuehler, José Luiz Catão-Dias, Mara Cristina Marques, Luciana Neves Torres, Manfred Reinacher and Regina Hofmann-Lehmann

    Virology Journal 2017 14:226

    Published on: 17 November 2017

  2. Research

    Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

    Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out ...

    Karolin Meixenberger, Kaveh Pouran Yousef, Maureen Rebecca Smith, Sybille Somogyi, Stefan Fiedler, Barbara Bartmeyer, Osamah Hamouda, Norbert Bannert, Max von Kleist and Claudia Kücherer

    Virology Journal 2017 14:223

    Published on: 14 November 2017

  3. Research

    A cheap and open HIV viral load technique applicable in routine analysis in a resource limited setting with a wide HIV genetic diversity

    HIV infection in Cameroon is characterized by a great viral diversity with all HIV-1 groups (M, N, O, and P) and HIV-2 in circulation. HIV group determination is very important if tailored viral load analysis ...

    Elodie Téclaire Ngo-Malabo, Paul Alain Ngoupo T., Martin Zekeng, Valérie Ngono, Laure Ngono, Serge Alain Sadeuh-Mba, Richard Njouom and Anfumbom Kfutwah

    Virology Journal 2017 14:224

    Published on: 14 November 2017

  4. Review

    Epidemiology and genetic diversity of bovine leukemia virus

    Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses....

    Meripet Polat, Shin-nosuke Takeshima and Yoko Aida

    Virology Journal 2017 14:209

    Published on: 2 November 2017

  5. Research

    Is MMTV associated with human breast cancer? Maybe, but probably not

    Conflicting results regarding the association of MMTV with human breast cancer have been reported. Published sequence data have indicated unique MMTV strains in some human samples. However, concerns regarding ...

    Raisa Perzova, Lynn Abbott, Patricia Benz, Steve Landas, Seema Khan, Jordan Glaser, Coleen K. Cunningham and Bernard Poiesz

    Virology Journal 2017 14:196

    Published on: 13 October 2017

  6. Research

    Membrane-anchored CCL20 augments HIV Env-specific mucosal immune responses

    Induction of broad immune responses at mucosal site remains a primary goal for most vaccines against mucosal pathogens. Abundance of evidence indicates that the co-delivery of mucosal adjuvants, including cyto...

    Xianliang Sun, Han Zhang, Shuiling Xu, Lili Shi, Jingjian Dong, Dandan Gao, Yan Chen and Hao Feng

    Virology Journal 2017 14:163

    Published on: 23 August 2017

  7. Research

    The impact of p53 on the early stage replication of retrovirus

    The function of p53 in cancer biology has been studied extensively, but its role in anti-retrovirus infection has been elusive for many years. The restriction of retrovirus early stage replication by p53 was i...

    Michaela Kinnetz, Faris Alghamdi, Michael Racz, Wenwei Hu and Binshan Shi

    Virology Journal 2017 14:151

    Published on: 9 August 2017

  8. Short report

    Prevalence of plasma autoantibody against cancer testis antigen NY-ESO-1 in HTLV-1 infected individuals with different clinical status

    Detection of specific immune responses against cancer/testis antigen NY-ESO-1 was recently reported in patients with adult T-cell leukemia/lymphoma (ATL) and human T-cell leukemia virus type 1 (HTLV-1)-infecte...

    Yasuo Shiohama, Tadasuke Naito, Toshio Matsuzaki, Reiko Tanaka, Takeaki Tomoyose, Hiroshi Takashima, Takuya Fukushima, Yuetsu Tanaka and Mineki Saito

    Virology Journal 2017 14:130

    Published on: 17 July 2017

  9. Research

    Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein

    The human immunodeficiency virus (HIV-1) envelope glycoprotein (Env), a Type 1 transmembrane protein, assembles into a trimeric spike complex that mediates virus entry into host cells. The high potential energ...

    Hanh T. Nguyen, Navid Madani, Haitao Ding, Emerald Elder, Amy Princiotto, Christopher Gu, Patrice Darby, James Alin, Alon Herschhorn, John C. Kappes, Youdong Mao and Joseph G. Sodroski

    Virology Journal 2017 14:33

    Published on: 16 February 2017

  10. Short report

    Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

    HIV-1 is highly variable genetically and at protein level, a property it uses to subvert antiviral immunity and treatment. The aim of this study was to assess if HIV subtype differences were associated with va...

    Rose C. Kitawi, Carol W. Hunja, Rashid Aman, Bernhards R. Ogutu, Anne W. T. Muigai, Gilbert O. Kokwaro and Washingtone Ochieng

    Virology Journal 2017 14:29

    Published on: 14 February 2017

  11. Short report

    The sense behind retroviral anti-sense transcription

    Retroviruses are known to rely extensively on the expression of viral proteins from the sense proviral genomic strand. Yet, the production of regulatory retroviral proteins from antisense-encoded viral genes i...

    Mamneet Manghera, Alycia Magnusson and Renée N. Douville

    Virology Journal 2017 14:9

    Published on: 14 January 2017

  12. Research

    Construction of a molecular clone of ovine enzootic nasal tumor virus

    Enzootic nasal tumor virus (ENTV-1) is an ovine betaretrovirus that has been linked to enzootic nasal adenocarcinoma (ENA), a contagious tumor of the ethmoid turbinates of sheep. Transmission experiments perfo...

    Scott R. Walsh, María Carla Rosales Gerpe and Sarah K. Wootton

    Virology Journal 2016 13:209

    Published on: 30 December 2016

  13. Research

    Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques

    Increasing evidence suggests an unexpected potential for non-neutralizing antibodies to prevent HIV infection. Consequently, identification of functional linear B-cell epitopes for HIV are important for develo...

    Bapi Pahar, Carys S. Kenway-Lynch, Preston Marx, Sudesh K. Srivastav, Celia LaBranche, David C. Montefiori and Arpita Das

    Virology Journal 2016 13:200

    Published on: 1 December 2016

  14. Short report

    Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro

    During sexual transmission of human immunodeficiency virus (HIV), macrophages are initial targets for HIV infection. Secretory leukocyte protease inhibitor (SLPI) has been shown to protect against HIV infectio...

    Andrew W. Woodham, Adriana M. Sanna, Julia R. Taylor, Joseph G. Skeate, Diane M. Da Silva, Lodewijk V. Dekker and W. Martin Kast

    Virology Journal 2016 13:187

    Published on: 18 November 2016

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