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Mucus and Mucins: do they have a role in the inhibition of the human immunodeficiency virus?

Many studies have shown that body fluids have components that prevent the transmission of HIV-1 from infected to non-infected persons through various forms of contact. This review explores the anti-HIV activity of various types body fluids, including saliva and breast milk, along with their respective mucin components. The authors then interrogate the possibility of exploiting mucins to formulate a biologically based biocompatible substance that could act as a topical prophylactic to prevent transmission of the virus.


  1. Content type: Research


    Authors: Josefina Garcia, Victoria Espejo, Martha Nelson, Merly Sovero, Manuel V Villaran, Jorge Gomez, Melvin Barrantes, Felix Sanchez, Guillermo Comach, Ana E Arango, Nicolas Aguayo, Ivette L de Rivera, Wilson Chicaiza, Mirna Jimenez, Washington Aleman, Francisco Rodriguez…

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Virology Journal is published continuously online-only. We encourage you to sign up to receive free email alerts to keep up to date with all of the latest articles by registering here.

Aims and scope

Virology Journal is an open access, peer reviewed journal that considers articles on all aspects of virology, including research on the viruses of animals, plants and microbes. The journal welcomes basic research as well as pre-clinical and clinical studies of novel diagnostic tools, vaccines and anti-viral therapies.

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Journal Sections

Emerging viruses: Tom Geisbert, University of Texas Medical Branch, USA
Hepatitis viruses: Alan McLachlan, University of Illinois at Chicago, USA
Herpes viruses: Blossom Damania, University of North Carolina at Chapel Hill, USA
Influenza viruses: Hualan Chen, Chinese Academy of Agricultural Sciences, China
Negative-strand RNA viruses: Bert Rima, Queen’s University Belfast, UK
Other viruses: Erna Geessien Kroon, Universidade Federal de Minas Gerais, Brazil
Plant viruses: Chikara Masuta, Hokkaido University, Japan
Positive-strand RNA viruses: Alexander A Khromykh, University of Queensland, Australia
Retroviruses: Li Wu, Ohio State University, USA
Veterinary DNA viruses: Klaus Osterrieder, Freie Universität Berlin, Germany
Veterinary RNA viruses: Siba Samal, University of Maryland, USA
Viruses of microbes: Joana Azeredo, University of Minho, Portugal

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Linfa Wang, Editor-in-Chief

Prof Wang is the director of the Programme in Emerging Infectious Diseases at Duke-NUS Medical School, and an honorary professor at the University of Melbourne and the Chinese Academy of Sciences. He is an international leader in the field of emerging zoonotic viruses and virus-host interaction, specialising in bat-borne viruses. After completing his Bachelor's degree in 1982 at the East China Normal University, he went on to obtain his PhD at the University of California, Davis. In 1990, he joined the CSIRO, Australian Animal Health Laboratory where he played a leading role in identifying bats as the natural host of the Severe Acute Respiratory Syndrome (SARS) virus. 

Prof Wang's work has been recognized internationally through various international awards, numerous invited speeches at major international conferences, many top scientific publications, five patents and many invited book chapters. He holds a number of honorary positions and memberships and has received numerous awards such as the 2014 Eureka Prize for Research in Infectious Diseases. In 2010, Prof Wang was elected as a Fellow of Australian Academy of Technological Sciences and Engineering in recognition of his expertise in new and emerging diseases.


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