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Retroviruses

Section Editor: Linda Chelico, University of Saskatchewan, Canada
Deputy Section Editor: Molly Ohainle, Fred Hutchinson Cancer Research Center, USA

The Retroviruses section of Virology Journal aims to publish research articles and reviews covering all aspects of human and animal retroviruses. We welcome basic and translational studies on the mechanisms of retrovirus replication and pathogenesis, including reports on the development of antiretroviral drugs and vaccines. Interdisciplinary research on retroviruses using multiple approaches is particularly welcome.

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  1. As the most frequent pathway of vertical transmission of HTLV-1 is breast-feeding, and considering the higher prevalence in women, it is very important to perform screening examinations for anti-HTLV-1 antibod...

    Authors: Marco Antônio Gomes Mello, Aline Ferreira da Conceição, Sandra Mara Bispo Sousa, Luiz Carlos Alcântara, Lauro Juliano Marin, Mônica Regina da Silva Raiol, Ney Boa-Sorte, Lucas Pereira Souza Santos, Maria da Conceição Chagas de Almeida, Tâmara Coutinho Galvão, Raquel Gois Bastos, Noilson Lázaro, Bernardo Galvão-Castro and Sandra Rocha Gadelha
    Citation: Virology Journal 2014 11:28
    Content type: Research Published on:

  2. Because of the shared transmission routes, co-infection with human immunodeficiency virus (HIV) and hepatitis C virus (HIV) is very common. Accumulated clinical evidence showed that one could alter the infecti...

    Authors: Lina Yi, Jin Zhao, Jing Lu, Ying Chen, Lin Chen, Jinquan Cheng, Yan Sun, Zhi Li, Ruotin Men, Li Yang, Hsiangfu Kung, Zhengrong Yang and Ming-liang He
    Citation: Virology Journal 2014 11:27
    Content type: Research Published on:

  3. Previously, we showed that the tetraspanin membrane protein CD63 mediates both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of CD63 were discerned using monoclonal antib...

    Authors: Guangyu Li, Mark A Endsley, Anoma Somasunderam, Sonia L Gbota, Maryann I Mbaka, James L Murray and Monique R Ferguson
    Citation: Virology Journal 2014 11:23
    Content type: Research Published on:

  4. We and others have previously reported that cell membrane-bound TGFβ (mTGFβ) on activated T regulatory (Treg) cells mediates suppressor function. Current findings suggest that a novel protein known as Glycopro...

    Authors: Michelle M Miller, Christopher S Petty, Mary B Tompkins and Jonathan E Fogle
    Citation: Virology Journal 2014 11:7
    Content type: Research Published on:

  5. Despite the significant contributions of monocytes to HIV persistence, the HIV-monocyte interaction remains elusive. For patients on antiretroviral therapy, previous studies observed a virological suppression ...

    Authors: Jing Qin Wu, Tara Ruth Sassé, Monica Miranda Saksena and Nitin K Saksena
    Citation: Virology Journal 2013 10:361
    Content type: Research Published on:

  6. Previously, we had shown that persons infected with human T-cell lymphoma leukemia virus 1 or 2 (HTLV-1 or 2) had an increased prevalence of antibodies to a peptide in the Pol protein of the retrovirus HERV-K1...

    Authors: Raisa Perzova, Elliot Graziano, Swathi Sanghi, Caitlin Welch, Patricia Benz, Lynn Abbott, Danielle Lalone, Jordan Glaser, Thomas Loughran, William Sheremata and Bernard J Poiesz
    Citation: Virology Journal 2013 10:360
    Content type: Research Published on:

  9. There is legitimate concern that minority drug-resistant mutants may be selected during the initial HIV-1 RNA decay phase following antiretroviral therapy initiation, thus undermining efficacy of treatment. Th...

    Authors: Marc Noguera-Julian, Maria Casadellà, Christian Pou, Cristina Rodríguez, Susana Pérez-Álvarez, Jordi Puig, Bonaventura Clotet and Roger Paredes
    Citation: Virology Journal 2013 10:350
    Content type: Short report Published on:

  10. Identification of the epitopes targeted by antibodies that can neutralize diverse HIV-1 strains can provide important clues for the design of a preventative vaccine.

    Authors: Miguel Lacerda, Penny L Moore, Nobubelo K Ngandu, Michael Seaman, Elin S Gray, Ben Murrell, Mohan Krishnamoorthy, Molati Nonyane, Maphuti Madiga, Constantinos Kurt Wibmer, Daniel Sheward, Robert T Bailer, Hongmei Gao, Kelli M Greene, Salim S Abdool Karim, John R Mascola…
    Citation: Virology Journal 2013 10:347
    Content type: Research Published on:

  11. OX40 ligand (OX40L) co-stimulates and differentiates T cells via ligation of OX40 that is transiently induced on T cells upon activation, resulting in prolonged T cell survival and enhanced cytokine production...

    Authors: Daigo Kasahara, Azusa Takara, Yoshiaki Takahashi, Akira Kodama, Reiko Tanaka, Aftab A Ansari and Yuetsu Tanaka
    Citation: Virology Journal 2013 10:338
    Content type: Research Published on:

  12. The etiology of fibromyalgia and chronic fatigue syndrome (FM/CFS) is currently unknown. A recurrent viral infection is an attractive hypothesis repeatedly found in the literature since it would explain the pe...

    Authors: Elisa Oltra, María García-Escudero, Armando Vicente Mena-Durán, Vicente Monsalve and Germán Cerdá-Olmedo
    Citation: Virology Journal 2013 10:332
    Content type: Research Published on:

  13. Foamy viruses are non-pathogenic in vivo and naturally infect all species of non-human primates (NHP). Simian foamy viruses (SFV) are highly prevalent in both free ranging and captive NHP but few longitudinal stu...

    Authors: Simon Hood, Jane L Mitchell, Meera Sethi, Neil M Almond, Keith L Cutler and Nicola J Rose
    Citation: Virology Journal 2013 10:326
    Content type: Research Published on:

  14. HIV in Chile has a notification rate of 0.01%. Coreceptor antagonists are a family of antiretroviral drugs that are used with the prior knowledge of patients HIV-1 tropism. Viral RNA-based tropism detection re...

    Authors: Pablo Ferrer, Luisa Montecinos, Mario Tello, Rocio Tordecilla, Consuelo Rodríguez, Marcela Ferrés, Carlos M Pérez, Carlos Beltrán, Maria A Guzmán and Alejandro Afani
    Citation: Virology Journal 2013 10:318
    Content type: Short report Published on:

  15. Acacia catechu (Mimosa family) stem bark extracts have been used traditionally as a dietary supplement as well as a folk medicine given its reported anti-inflammatory, immunomodulatory, hepatoprotective, antioxid...

    Authors: Nutan, Manoj Modi, Charlene S Dezzutti, Shweta Kulshreshtha, Ajay Kumar Singh Rawat, Sharad Kumar Srivastava, Swadesh Malhotra, Anjali Verma, Udaykumar Ranga and Satish Kumar Gupta
    Citation: Virology Journal 2013 10:309
    Content type: Research Published on:

  16. HIV trans-activator protein (Tat) is the crucial factor to control HIV transcription, and is usually considered as an important immunogen for the design of HIV vaccine. Recent studies reported some special bio...

    Authors: Ye Liu, Fusheng Li, Zhi Qi, Yanling Hao, Kunxue Hong, Yong Liu, Yulong Cong and Yiming Shao
    Citation: Virology Journal 2013 10:297
    Content type: Research Published on:

  18. Since Highly Active Antiretroviral Therapy (HAART) medications were made available in 2002, multiple serious side effects have been observed. However, no study has yet systematically evaluated the prevalence o...

    Authors: Jiang Xiao, Ning Han, Di Yang and Hongxin Zhao
    Citation: Virology Journal 2013 10:261
    Content type: Research Published on:

  19. Dendritic cells (DCs) are promising mediators of anti-tumor immune responses due to their potent antigen-presentation capacity. Unfortunately, cancer cells can often disarm differentiated DCs by rendering them...

    Authors: James CM Wang, Tânia C Felizardo, Bryan CY Au, Daniel H Fowler, Gregory A Dekaban and Jeffrey A Medin
    Citation: Virology Journal 2013 10:240
    Content type: Methodology Published on:

  21. Integration of double stranded viral DNA is a key step in the retroviral life cycle. Virally encoded enzyme, integrase, plays a central role in this reaction. Mature forms of integrase of several retroviruses ...

    Authors: Guney Boso, Takafumi Tasaki, Yong Tae Kwon and Nikunj V Somia
    Citation: Virology Journal 2013 10:233
    Content type: Research Published on:

  22. Protein arginine methyltransferase 6 (PRMT6) can methylate the HIV-1 Tat, Rev and nucleocapsid proteins in a manner that diminishes each of their functions in in vitro assays, and increases the stability of Tat i...

    Authors: Haran Sivakumaran, Min-Hsuan Lin, Ann Apolloni, Vincent Cutillas, Hongping Jin, Dongsheng Li, Ting Wei and David Harrich
    Citation: Virology Journal 2013 10:207
    Content type: Research Published on:

  23. Osteosarcomas are the most common primary bone malignancies found in children and adolescents. An optimized system was developed for efficient retroviral gene delivery into solid 143B osteosarcoma tumors in mi...

    Authors: Xia Zhang, Anindita Sarangi, Dai-Tze Wu, Jaya Kanduri and Monica J Roth
    Citation: Virology Journal 2013 10:194
    Content type: Short report Published on:

  24. A neuropathogenic variant of Friend murine leukemia virus (Fr-MLV) clone A8 induces spongiform neurodegeneration when infected into neonatal rats. Studies with chimeras constructed from the A8 virus and the no...

    Authors: Yeng Cheng Choo, Yohei Seki, Akihito Machinaga, Nobuo Ogita and Sayaka Takase-Yoden
    Citation: Virology Journal 2013 10:124
    Content type: Research Published on:
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  • ISSN: 1743-422X (electronic)

Virology Journal

ISSN: 1743-422X