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Influenza viruses

Section Editor: Hualan Chen, Chinese Academy of Agricultural Sciences, China 
Deputy Section Editor: Chengjun Li, Chinese Academy of Agricultural Sciences, China

The Influenza viruses section of Virology Journal will publish articles on all aspects of influenza virus research, including molecular genetics, molecular biology, biochemistry, biophysics, structural biology, cell biology, immunology, morphology, and pathogenesis. The section will also welcome the case reports of influenza outbreaks in both human and animal populations, and development and evaluation of vaccines and antiviral compounds in humans and animals.​​​​​​​

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  1. The predominant subtypes of swine influenza A virus (SIV) in Korea swine population are H1N1, H1N2, and H3N2. The viruses are genetically close to the classical U.S. H1N1 and triple-reassortant H1N2 and H3N2 v...

    Authors: Kwang-Soo Lyoo, Jeong-Ki Kim, Kwonil Jung, Bo-Kyu Kang and Daesub Song

    Citation: Virology Journal 2014 11:170

    Content type: Short report

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  2. Major histocompatibility complex (MHC) class I peptide binding and presentation are essential for antigen-specific activation of cytotoxic T lymphocytes (CTLs) and swine MHC class I molecules, also termed swin...

    Authors: Lasse E Pedersen, Solvej Ø Breum, Ulla Riber, Lars E Larsen and Gregers Jungersen

    Citation: Virology Journal 2014 11:163

    Content type: Short report

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  3. H3N8 equine influenza virus (EIV) has caused disease outbreaks in horses across the world since its first isolation in 1963. However, unlike human, swine and avian influenza, there is relatively little sequenc...

    Authors: Adam Rash, Alana Woodward, Neil Bryant, John McCauley and Debra Elton

    Citation: Virology Journal 2014 11:159

    Content type: Methodology

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  4. Influenza is a segmented negative strand RNA virus. Each RNA segment is encapsulated by influenza nucleoprotein and bound by the viral RNA dependent RNA polymerase (RdRP) to form viral ribonucleoproteins respo...

    Authors: Sean Larsen, Steven Bui, Veronica Perez, Adeba Mohammad, Hilario Medina-Ramirez and Laura L Newcomb

    Citation: Virology Journal 2014 11:154

    Content type: Research

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  5. During the early phases of the 2009 pandemic, subjects with influenza-like illness only had laboratory testing specific for the new A(H1N1)pdm09 virus.

    Authors: Vigneswary Mala Ratnamohan, Janette Taylor, Frank Zeng, Kenneth McPhie, Christopher C Blyth, Sheena Adamson, Jen Kok and Dominic E Dwyer

    Citation: Virology Journal 2014 11:113

    Content type: Short report

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  6. Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when adminis...

    Authors: Tila Khan, Connie L Heffron, Kevin P High and Paul C Roberts

    Citation: Virology Journal 2014 11:78

    Content type: Short report

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  7. Wild waterfowl are recognized as the natural reservoir for influenza A viruses. Two distinct lineages, the American and Eurasian lineages, have been identified in wild birds. Gene flow between the two lineages...

    Authors: Yun Zhu, Shixiong Hu, Tian Bai, Lei Yang, Xiang Zhao, Wenfei Zhu, Yiwei Huang, Zhihong Deng, Hong Zhang, Zhiyong Bai, Mingdong Yu, Jianfei Huang and Yuelong Shu

    Citation: Virology Journal 2014 11:77

    Content type: Research

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  8. H5 low pathogenic avian influenza virus (LPAIV) infection in domestic ducks is a major problem in duck producing countries. Their silent circulation is an ongoing source of potential highly pathogenic or zoono...

    Authors: Olivier Guionie, Éric Niqueux, Michel Amelot, Stéphanie Bougeard and Véronique Jestin

    Citation: Virology Journal 2014 11:74

    Content type: Short report

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  9. Convalescent plasma and fractionated immunoglobulins have been suggested as prophylactic or therapeutic interventions during an influenza pandemic.

    Authors: Christine Hohenadl, Walter Wodal, Astrid Kerschbaum, Richard Fritz, M Keith Howard, Maria R Farcet, Daniel Portsmouth, John K McVey, Donald A Baker, Hartmut J Ehrlich, P Noel Barrett and Thomas R Kreil

    Citation: Virology Journal 2014 11:70

    Content type: Short report

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  10. We generated novel, effective candidate vaccine against Brucella abortus based on recombinant influenza viruses expressing the Brucella ribosomal protein L7/L12 or outer membrane protein (Omp)-16 from the NS1 ope...

    Authors: Kaissar Tabynov, Abylai Sansyzbay, Zhailaubay Kydyrbayev, Bolat Yespembetov, Sholpan Ryskeldinova, Nadezhda Zinina, Nurika Assanzhanova, Kulaisan Sultankulova, Nurlan Sandybayev, Berik Khairullin, Irina Kuznetsova, Boris Ferko and Andrej Egorov

    Citation: Virology Journal 2014 11:69

    Content type: Research

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  11. Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infe...

    Authors: Jin Lv, Yanhong Hua, Dan Wang, Aofei Liu, Juan An, Aimin Li, Yanfeng Wang, Xiliang Wang, Na Jia and Qisheng Jiang

    Citation: Virology Journal 2014 11:57

    Content type: Research

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  12. Influenza A virus has a wide range of hosts. It has not only infected human, but also been reported interspecies transmission from humans to other animals, such as pigs, poultry, dogs and cats. However, preval...

    Authors: Fu-Rong Zhao, Chun-Guo Liu, Xin Yin, Dong-Hui Zhou, Ping Wei and Hui-Yun Chang

    Citation: Virology Journal 2014 11:49

    Content type: Short report

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  13. Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses (ILIs) remain largely unknown in developing countries. This study represen...

    Authors: Julie Delangue, Yelin Roca Sanchez, Géraldine Piorkowski, Maël Bessaud, Cécile Baronti, Laurence Thirion-Perrier, Roxana Loayza Mafayle, Cinthia Avila Ardaya, Gabriela Añez Aguilera, Jimmy Revollo Guzman, Javier Lora Riera and Xavier de Lamballerie

    Citation: Virology Journal 2014 11:35

    Content type: Research

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  14. Regular reformulation of currently available vaccines is necessary due to the unpredictable variability of influenza viruses. Therefore, vaccine based on a highly conserved antigen with capability of induction...

    Authors: Mohammed YE Chowdhury, Soo-Kyung Seo, Ho-Jin Moon, Melbourne R Talactac, Jae-Hoon Kim, Min-Eun Park, Hwa-Young Son, Jong-Soo Lee and Chul-Joong Kim

    Citation: Virology Journal 2014 11:21

    Content type: Research

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  15. Highly pathogenic avian influenza virus (HPAIV) is a highly contagious disease which is a zoonotic pathogen of significant economic and public health concern. The outbreaks caused by HPAIV H5N1 of Asian origin...

    Authors: Hua Chang, Feiyan Dai, Zili Liu, Feizhou Yuan, Siyue Zhao, Xun Xiang, Fengcai Zou, Bangquan Zeng, YaTing Fan and Gang Duan

    Citation: Virology Journal 2014 11:18

    Content type: Research

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  16. Following the 2009 swine flu pandemic, a cohort for pandemic influenza (CoPanFlu) study was established in Djibouti, the Horn of Africa, to investigate its case prevalence and risk predictors’ at household level.

    Authors: Fred Andayi, Pascal Crepey, Alexia Kieffer, Nicolas Salez, Ammar A Abdo, Fabrice Carrat, Antoine Flahault and Xavier de Lamballerie

    Citation: Virology Journal 2014 11:13

    Content type: Research

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  17. The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 10 (2013). The success of any scientific journal depends on an effective and strict peer review ...

    Authors: Linfa Wang

    Citation: Virology Journal 2014 11:4

    Content type: Reviewer acknowledgement

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  18. Influenza A virus (IAV) neuraminidase (NA) cleaves sialic acids (Sias) from glycans. Inhibiting NA with oseltamivir suppresses both viral infection, and viral release from cultured human airway epithelial cell...

    Authors: Miriam Cohen, Xing-Quan Zhang, Hooman P Senaati, Hui-Wen Chen, Nissi M Varki, Robert T Schooley and Pascal Gagneux

    Citation: Virology Journal 2013 10:321

    Content type: Research

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  19. Avian influenza virus (AIV) induced proinflammatory cytokine expression is believed to contribute to the disease pathogenesis following infection of poultry. However, there is limited information on the avian ...

    Authors: Haijun Jiang, Kangzhen Yu and Darrell R Kapczynski

    Citation: Virology Journal 2013 10:342

    Content type: Research

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  20. This study was carried out to determine causative agents of acute respiratory illness of patients in Khartoum State, Sudan.

    Authors: Khalid A Enan, Takeshi Nabeshima, Toru Kubo, Corazon C Buerano, Abdel Rahim M El Hussein, Isam M Elkhidir, Eltahir AG Khalil and Kouichi Morita

    Citation: Virology Journal 2013 10:312

    Content type: Research

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  21. The pathological damage inflicted by virulent AIV strains is often caused by inducing a positive feedback loop of cytokines in immune cells that cause excessive inflammation. Previous research has shown that a...

    Authors: Shuang Tong, Jin Tian, Heng Wang, Zhiqiang Huang, Meng Yu, Lingshuang Sun, Rongchang Liu, Ming Liao and Zhangyong Ning

    Citation: Virology Journal 2013 10:296

    Content type: Research

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  22. Influenza virus undergoes constant antigenic evolution, and therefore influenza vaccines must be reformulated each year. Time is necessary to produce a vaccine that is antigenically matched to a pandemic strai...

    Authors: Song Yang, Shumeng Niu, Zhihua Guo, Ye Yuan, Kun Xue, Sinan Liu and Hong Jin

    Citation: Virology Journal 2013 10:291

    Content type: Research

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  23. The influenza A virus subtypes H1N1, H1N2 and H3N2 are the most prevalent subtypes in swine. In 2003, a reassorted H1N2 swine influenza virus (SIV) subtype appeared and became prevalent in Denmark. In the pres...

    Authors: Ramona Trebbien, Karoline Bragstad, Lars Erik Larsen, Jens Nielsen, Anette Bøtner, Peter MH Heegaard, Anders Fomsgaard, Birgitte Viuff and Charlotte Kristiane Hjulsager

    Citation: Virology Journal 2013 10:290

    Content type: Research

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  24. In the spring of 2013, a novel avian-origin influenza A (H7N9) virus in Eastern China emerged causing human infections. Concerns that a new influenza pandemic could occur were raised. The potential effect of c...

    Authors: Shumei Zou, Junfeng Guo, Rongbao Gao, Libo Dong, Jianfang Zhou, Ye Zhang, Jie Dong, Hong Bo, Kun Qin and Yuelong Shu

    Citation: Virology Journal 2013 10:289

    Content type: Research

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  25. Highly pathogenic avian influenza (HPAI) viruses pose a potential human health threat as they can be transmitted directly from infected poultry to humans. During a large outbreak of HPAI H7N7 virus among poult...

    Authors: Rineke MC de Jong, Norbert Stockhofe-Zurwieden, Eline S Verheij, Els A de Boer-Luijtze, Saskia JM Ruiter, Olav S de Leeuw and Lisette AHM Cornelissen

    Citation: Virology Journal 2013 10:276

    Content type: Research

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  26. The current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.

    Authors: Lili Xu, Linlin Bao, Wei Deng, Hua Zhu, Ting Chen, Qi Lv, Fengdi Li, Jing Yuan, Zhiguang Xiang, Kai Gao, Yanfeng Xu, Lan Huang, Yanhong Li, Jiangning Liu, Yanfeng Yao, Pin Yu…

    Citation: Virology Journal 2013 10:253

    Content type: Short report

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    The Correction to this article has been published in Virology Journal 2020 17:83

  27. Serological investigations of swine influenza virus infections and epidemiological conclusions thereof are challenging due to the complex and regionally variable pattern of co-circulating viral subtypes and li...

    Authors: Na Zhao, Elke Lange, Sybille Kubald, Christian Grund, Martin Beer and Timm C Harder

    Citation: Virology Journal 2013 10:246

    Content type: Research

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  28. The genetic basis for avian to mammalian host switching in influenza A virus is largely unknown. The human A/HK/156/1997 (H5N1) virus that transmitted from poultry possesses NS1 gene mutations F103L + M106I th...

    Authors: Samar K Dankar, Elena Miranda, Nicole E Forbes, Martin Pelchat, Ali Tavassoli, Mohammed Selman, Jihui Ping, Jianjun Jia and Earl G Brown

    Citation: Virology Journal 2013 10:243

    Content type: Research

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  29. The endemic H5N1 high pathogenicity avian influenza virus (A/H5N1) in poultry in Egypt continues to cause heavy losses in poultry and poses a significant threat to human health.

    Authors: Elham F El-Zoghby, Mona M Aly, Soad A Nasef, Mohamed K Hassan, Abdel-Satar Arafa, Abdullah A Selim, Shereen G Kholousy, Walid H Kilany, Marwa Safwat, E M Abdelwhab and Hafez M Hafez

    Citation: Virology Journal 2013 10:203

    Content type: Research

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