Skip to content

Advertisement

Influenza viruses

Section Editor: Hualan Chen, Chinese Academy of Agricultural Sciences, China 
Deputy Section Editor: Chengjun Li, Chinese Academy of Agricultural Sciences, China

The Influenza viruses section of Virology Journal will publish articles on all aspects of influenza virus research, including molecular genetics, molecular biology, biochemistry, biophysics, structural biology, cell biology, immunology, morphology, and pathogenesis. The section will also welcome the case reports of influenza outbreaks in both human and animal populations, and development and evaluation of vaccines and antiviral compounds in humans and animals.​​​​​​​

Page 2 of 2

  1. Content type: Research

    The prevalence of avian H9N2 viruses throughout Asia, along with their demonstrated ability to infect mammals, puts them high on the list of influenza viruses with pandemic potential for humans. In this study,...

    Authors: Chuanmei Zhang, Yang Xuan, Hu Shan, Haiyan Yang, Jianlin Wang, Ke Wang, Guimei Li and Jian Qiao

    Citation: Virology Journal 2015 12:180

    Published on:

  2. Content type: Short report

    Detection of specific respiratory viruses is important for surveillance programs, where nasopharyngeal or nasal swabs have traditionally been used. Our objective was to determine whether sampling with a throat...

    Authors: Mohsin Ali, Sangsu Han, Chris J. Gunst, Steve Lim, Kathy Luinstra and Marek Smieja

    Citation: Virology Journal 2015 12:178

    Published on:

  3. Content type: Research

    The global outbreak of a novel swine-origin strain of the 2009 H1N1 influenza A virus and the sudden, worldwide increase in oseltamivir-resistant H1N1 influenza A viruses highlight the urgent need for novel an...

    Authors: Eun-Ha Kim, Young-Ki Choi, Chul-Joong Kim, Moon-Hee Sung and Haryoung Poo

    Citation: Virology Journal 2015 12:160

    Published on:

  4. Content type: Research

    The H10 subtype avian influenza viruses (H10N4, H10N5 and H10N7) have been reported to cause disease in mammals, and the first human case of H10N8 subtype avian influenza virus was reported in 2013. Recently, ...

    Authors: Sisi Luo, Zhixun Xie, Liji Xie, Jiabo Liu, Zhiqin Xie, Xianwen Deng, Li Huang, Jiaoling Huang, Tingting Zeng and Mazhar I. Khan

    Citation: Virology Journal 2015 12:145

    Published on:

  5. Content type: Short report

    Wild ducks play an important role in the evolution of avian influenza viruses (AIVs). Domestic ducks in China are known to carry and spread H9N2 AIVs that are thought to have contributed internal genes for the...

    Authors: Qiaoyang Teng, Weixia Shen, Qinfang Liu, Guangyu Rong, Lin Chen, Xuesong Li, Hongjun Chen, Jianmei Yang and Zejun Li

    Citation: Virology Journal 2015 12:143

    Published on:

  6. Content type: short report

    Since avian-origin H3N2 canine influenza virus (CIV) was first identified in South Korea in 2008, the novel influenza virus has been reported in several countries in Asia. Reverse zoonotic transmission of pand...

    Authors: Woonsung Na, Kwang-Soo Lyoo, Eun-jung Song, Minki Hong, Minjoo Yeom, Hyoungjoon Moon, Bo-Kyu Kang, Doo-Jin Kim, Jeong-Ki Kim and Daesub Song

    Citation: Virology Journal 2015 12:134

    Published on:

  7. Content type: Research

    Influenza A viruses (IAVs) are important pathogens that affect the health of humans and many additional animal species. IAVs are enveloped, negative single-stranded RNA viruses whose genome encodes at least te...

    Authors: Alex Generous, Molly Thorson, Jeff Barcus, Joseph Jacher, Marc Busch and Heidi Sleister

    Citation: Virology Journal 2014 11:228

    Published on:

  8. Content type: Short report

    With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to...

    Authors: Liesbeth Van Wesenbeeck, Hanne Meeuws, David D’Haese, Gabriela Ispas, Lieselot Houspie, Marc Van Ranst and Lieven J Stuyver

    Citation: Virology Journal 2014 11:233

    Published on:

  9. Content type: Research

    Highly pathogenic avian influenza (HPAI) H5N1 viruses continue to circulate in poultry and can infect and cause mortality in birds and mammals; the genetic determinants of their increased virulence are largely...

    Authors: Kairat Tabynov, Abylay Sansyzbay, Nurlan Sandybayev and Muratbay Mambetaliyev

    Citation: Virology Journal 2014 11:207

    Published on:

  10. Content type: Research

    The avian influenza virus (AIV) causes frequent disease with high morbidity and mortality. RNA interference (RNAi) has been shown to provide an effective antiviral defense in animals, and several studies have ...

    Authors: Shuang Wang, Peng Zhang, Fei He, Ji-Gui Wang, Jia-Zeng Sun, Zhi-Li Li, Bao Yi, Ji Xi, Ya-Ping Mao, Qiang Hou, Dao-Li Yuan, Zi-Ding Zhang and Wei-Quan Liu

    Citation: Virology Journal 2014 11:208

    Published on:

  11. Content type: Research

    Data about molecular diversity of commonly circulating type A influenza viruses in Ontario swine are scarce. Yet, this information is essential for surveillance of animal and public health, vaccine updates, an...

    Authors: Helena Grgić, Marcio Costa, Robert M Friendship, Susy Carman, Éva Nagy, Greg Wideman, Scott Weese and Zvonimir Poljak

    Citation: Virology Journal 2014 11:194

    Published on:

  12. Content type: Research

    On 19 February 2013, the first patient infected with a novel influenza A H7N9 virus from an avian source showed symptoms of sickness. More than 349 laboratory-confirmed cases and 109 deaths have been reported ...

    Authors: Linlin Bao, Lili Xu, Hua Zhu, Wei Deng, Ting Chen, Qi Lv, Fengdi Li, Jing Yuan, Yanfeng Xu, Lan Huang, Yanhong Li, Jiangning Liu, Yanfeng Yao, Pin Yu, Honglin Chen and Chuan Qin

    Citation: Virology Journal 2014 11:185

    Published on:

  13. Content type: Short report

    The predominant subtypes of swine influenza A virus (SIV) in Korea swine population are H1N1, H1N2, and H3N2. The viruses are genetically close to the classical U.S. H1N1 and triple-reassortant H1N2 and H3N2 v...

    Authors: Kwang-Soo Lyoo, Jeong-Ki Kim, Kwonil Jung, Bo-Kyu Kang and Daesub Song

    Citation: Virology Journal 2014 11:170

    Published on:

  14. Content type: Short report

    Major histocompatibility complex (MHC) class I peptide binding and presentation are essential for antigen-specific activation of cytotoxic T lymphocytes (CTLs) and swine MHC class I molecules, also termed swin...

    Authors: Lasse E Pedersen, Solvej Ø Breum, Ulla Riber, Lars E Larsen and Gregers Jungersen

    Citation: Virology Journal 2014 11:163

    Published on:

  15. Content type: Methodology

    H3N8 equine influenza virus (EIV) has caused disease outbreaks in horses across the world since its first isolation in 1963. However, unlike human, swine and avian influenza, there is relatively little sequenc...

    Authors: Adam Rash, Alana Woodward, Neil Bryant, John McCauley and Debra Elton

    Citation: Virology Journal 2014 11:159

    Published on:

  16. Content type: Research

    Influenza is a segmented negative strand RNA virus. Each RNA segment is encapsulated by influenza nucleoprotein and bound by the viral RNA dependent RNA polymerase (RdRP) to form viral ribonucleoproteins respo...

    Authors: Sean Larsen, Steven Bui, Veronica Perez, Adeba Mohammad, Hilario Medina-Ramirez and Laura L Newcomb

    Citation: Virology Journal 2014 11:154

    Published on:

  17. Content type: Short report

    During the early phases of the 2009 pandemic, subjects with influenza-like illness only had laboratory testing specific for the new A(H1N1)pdm09 virus.

    Authors: Vigneswary Mala Ratnamohan, Janette Taylor, Frank Zeng, Kenneth McPhie, Christopher C Blyth, Sheena Adamson, Jen Kok and Dominic E Dwyer

    Citation: Virology Journal 2014 11:113

    Published on:

  18. Content type: Short report

    Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when adminis...

    Authors: Tila Khan, Connie L Heffron, Kevin P High and Paul C Roberts

    Citation: Virology Journal 2014 11:78

    Published on:

  19. Content type: Research

    Wild waterfowl are recognized as the natural reservoir for influenza A viruses. Two distinct lineages, the American and Eurasian lineages, have been identified in wild birds. Gene flow between the two lineages...

    Authors: Yun Zhu, Shixiong Hu, Tian Bai, Lei Yang, Xiang Zhao, Wenfei Zhu, Yiwei Huang, Zhihong Deng, Hong Zhang, Zhiyong Bai, Mingdong Yu, Jianfei Huang and Yuelong Shu

    Citation: Virology Journal 2014 11:77

    Published on:

  20. Content type: Short report

    H5 low pathogenic avian influenza virus (LPAIV) infection in domestic ducks is a major problem in duck producing countries. Their silent circulation is an ongoing source of potential highly pathogenic or zoono...

    Authors: Olivier Guionie, Éric Niqueux, Michel Amelot, Stéphanie Bougeard and Véronique Jestin

    Citation: Virology Journal 2014 11:74

    Published on:

  21. Content type: Short report

    Convalescent plasma and fractionated immunoglobulins have been suggested as prophylactic or therapeutic interventions during an influenza pandemic.

    Authors: Christine Hohenadl, Walter Wodal, Astrid Kerschbaum, Richard Fritz, M Keith Howard, Maria R Farcet, Daniel Portsmouth, John K McVey, Donald A Baker, Hartmut J Ehrlich, P Noel Barrett and Thomas R Kreil

    Citation: Virology Journal 2014 11:70

    Published on:

  22. Content type: Research

    We generated novel, effective candidate vaccine against Brucella abortus based on recombinant influenza viruses expressing the Brucella ribosomal protein L7/L12 or outer membrane protein (Omp)-16 from the NS1 ope...

    Authors: Kaissar Tabynov, Abylai Sansyzbay, Zhailaubay Kydyrbayev, Bolat Yespembetov, Sholpan Ryskeldinova, Nadezhda Zinina, Nurika Assanzhanova, Kulaisan Sultankulova, Nurlan Sandybayev, Berik Khairullin, Irina Kuznetsova, Boris Ferko and Andrej Egorov

    Citation: Virology Journal 2014 11:69

    Published on:

  23. Content type: Research

    Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infe...

    Authors: Jin Lv, Yanhong Hua, Dan Wang, Aofei Liu, Juan An, Aimin Li, Yanfeng Wang, Xiliang Wang, Na Jia and Qisheng Jiang

    Citation: Virology Journal 2014 11:57

    Published on:

  24. Content type: Short report

    Influenza A virus has a wide range of hosts. It has not only infected human, but also been reported interspecies transmission from humans to other animals, such as pigs, poultry, dogs and cats. However, preval...

    Authors: Fu-Rong Zhao, Chun-Guo Liu, Xin Yin, Dong-Hui Zhou, Ping Wei and Hui-Yun Chang

    Citation: Virology Journal 2014 11:49

    Published on:

  25. Content type: Research

    Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses (ILIs) remain largely unknown in developing countries. This study represen...

    Authors: Julie Delangue, Yelin Roca Sanchez, Géraldine Piorkowski, Maël Bessaud, Cécile Baronti, Laurence Thirion-Perrier, Roxana Loayza Mafayle, Cinthia Avila Ardaya, Gabriela Añez Aguilera, Jimmy Revollo Guzman, Javier Lora Riera and Xavier de Lamballerie

    Citation: Virology Journal 2014 11:35

    Published on:

  26. Content type: Research

    Regular reformulation of currently available vaccines is necessary due to the unpredictable variability of influenza viruses. Therefore, vaccine based on a highly conserved antigen with capability of induction...

    Authors: Mohammed YE Chowdhury, Soo-Kyung Seo, Ho-Jin Moon, Melbourne R Talactac, Jae-Hoon Kim, Min-Eun Park, Hwa-Young Son, Jong-Soo Lee and Chul-Joong Kim

    Citation: Virology Journal 2014 11:21

    Published on:

  27. Content type: Research

    Highly pathogenic avian influenza virus (HPAIV) is a highly contagious disease which is a zoonotic pathogen of significant economic and public health concern. The outbreaks caused by HPAIV H5N1 of Asian origin...

    Authors: Hua Chang, Feiyan Dai, Zili Liu, Feizhou Yuan, Siyue Zhao, Xun Xiang, Fengcai Zou, Bangquan Zeng, YaTing Fan and Gang Duan

    Citation: Virology Journal 2014 11:18

    Published on:

  28. Content type: Research

    Following the 2009 swine flu pandemic, a cohort for pandemic influenza (CoPanFlu) study was established in Djibouti, the Horn of Africa, to investigate its case prevalence and risk predictors’ at household level.

    Authors: Fred Andayi, Pascal Crepey, Alexia Kieffer, Nicolas Salez, Ammar A Abdo, Fabrice Carrat, Antoine Flahault and Xavier de Lamballerie

    Citation: Virology Journal 2014 11:13

    Published on:

  29. Content type: Reviewer acknowledgement

    The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 10 (2013). The success of any scientific journal depends on an effective and strict peer review ...

    Authors: Linfa Wang

    Citation: Virology Journal 2014 11:4

    Published on:

  30. Content type: Research

    Influenza A virus (IAV) neuraminidase (NA) cleaves sialic acids (Sias) from glycans. Inhibiting NA with oseltamivir suppresses both viral infection, and viral release from cultured human airway epithelial cell...

    Authors: Miriam Cohen, Xing-Quan Zhang, Hooman P Senaati, Hui-Wen Chen, Nissi M Varki, Robert T Schooley and Pascal Gagneux

    Citation: Virology Journal 2013 10:321

    Published on:

  31. Content type: Research

    Avian influenza virus (AIV) induced proinflammatory cytokine expression is believed to contribute to the disease pathogenesis following infection of poultry. However, there is limited information on the avian ...

    Authors: Haijun Jiang, Kangzhen Yu and Darrell R Kapczynski

    Citation: Virology Journal 2013 10:342

    Published on:

  32. Content type: Research

    This study was carried out to determine causative agents of acute respiratory illness of patients in Khartoum State, Sudan.

    Authors: Khalid A Enan, Takeshi Nabeshima, Toru Kubo, Corazon C Buerano, Abdel Rahim M El Hussein, Isam M Elkhidir, Eltahir AG Khalil and Kouichi Morita

    Citation: Virology Journal 2013 10:312

    Published on:

  33. Content type: Research

    The pathological damage inflicted by virulent AIV strains is often caused by inducing a positive feedback loop of cytokines in immune cells that cause excessive inflammation. Previous research has shown that a...

    Authors: Shuang Tong, Jin Tian, Heng Wang, Zhiqiang Huang, Meng Yu, Lingshuang Sun, Rongchang Liu, Ming Liao and Zhangyong Ning

    Citation: Virology Journal 2013 10:296

    Published on:

  34. Content type: Research

    Influenza virus undergoes constant antigenic evolution, and therefore influenza vaccines must be reformulated each year. Time is necessary to produce a vaccine that is antigenically matched to a pandemic strai...

    Authors: Song Yang, Shumeng Niu, Zhihua Guo, Ye Yuan, Kun Xue, Sinan Liu and Hong Jin

    Citation: Virology Journal 2013 10:291

    Published on:

  35. Content type: Research

    The influenza A virus subtypes H1N1, H1N2 and H3N2 are the most prevalent subtypes in swine. In 2003, a reassorted H1N2 swine influenza virus (SIV) subtype appeared and became prevalent in Denmark. In the pres...

    Authors: Ramona Trebbien, Karoline Bragstad, Lars Erik Larsen, Jens Nielsen, Anette Bøtner, Peter MH Heegaard, Anders Fomsgaard, Birgitte Viuff and Charlotte Kristiane Hjulsager

    Citation: Virology Journal 2013 10:290

    Published on:

  36. Content type: Research

    In the spring of 2013, a novel avian-origin influenza A (H7N9) virus in Eastern China emerged causing human infections. Concerns that a new influenza pandemic could occur were raised. The potential effect of c...

    Authors: Shumei Zou, Junfeng Guo, Rongbao Gao, Libo Dong, Jianfang Zhou, Ye Zhang, Jie Dong, Hong Bo, Kun Qin and Yuelong Shu

    Citation: Virology Journal 2013 10:289

    Published on:

  37. Content type: Research

    Highly pathogenic avian influenza (HPAI) viruses pose a potential human health threat as they can be transmitted directly from infected poultry to humans. During a large outbreak of HPAI H7N7 virus among poult...

    Authors: Rineke MC de Jong, Norbert Stockhofe-Zurwieden, Eline S Verheij, Els A de Boer-Luijtze, Saskia JM Ruiter, Olav S de Leeuw and Lisette AHM Cornelissen

    Citation: Virology Journal 2013 10:276

    Published on:

  38. Content type: Short report

    The current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.

    Authors: Lili Xu, Linlin Bao, Wei Deng, Hua Zhu, Ting Chen, Qi Lv, Fengdi Li, Jing Yuan, Zhiguang Xiang, Kai Gao, Yanfeng Xu, Lan Huang, Yanhong Li, Jiangning Liu, Yanfeng Yao, Pin Yu…

    Citation: Virology Journal 2013 10:253

    Published on:

  39. Content type: Research

    Serological investigations of swine influenza virus infections and epidemiological conclusions thereof are challenging due to the complex and regionally variable pattern of co-circulating viral subtypes and li...

    Authors: Na Zhao, Elke Lange, Sybille Kubald, Christian Grund, Martin Beer and Timm C Harder

    Citation: Virology Journal 2013 10:246

    Published on:

  40. Content type: Research

    The genetic basis for avian to mammalian host switching in influenza A virus is largely unknown. The human A/HK/156/1997 (H5N1) virus that transmitted from poultry possesses NS1 gene mutations F103L + M106I th...

    Authors: Samar K Dankar, Elena Miranda, Nicole E Forbes, Martin Pelchat, Ali Tavassoli, Mohammed Selman, Jihui Ping, Jianjun Jia and Earl G Brown

    Citation: Virology Journal 2013 10:243

    Published on:

  41. Content type: Research

    The endemic H5N1 high pathogenicity avian influenza virus (A/H5N1) in poultry in Egypt continues to cause heavy losses in poultry and poses a significant threat to human health.

    Authors: Elham F El-Zoghby, Mona M Aly, Soad A Nasef, Mohamed K Hassan, Abdel-Satar Arafa, Abdullah A Selim, Shereen G Kholousy, Walid H Kilany, Marwa Safwat, E M Abdelwhab and Hafez M Hafez

    Citation: Virology Journal 2013 10:203

    Published on: