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Hepatitis viruses

Section Editor: Alan McLachlan, University of Illinois at Chicago, USA 
Deputy Section Editor: Susan Uprichard, Loyola University Medical Center​​​​​​​, USA 

The Hepatitis viruses section of Virology Journal includes studies relating to all aspects of hepatitis A, B C, D and E virus research including research discoveries addressing both basic and medical aspects of the biology of these human pathogens. Basic research topics of interest include all aspects of the viral life cycle (e.g. viral entry, intracellular capsid transport and disassembly, viral gene expression/regulation, protein processing/regulation, viral genome replication, particle assembly and egress) and viral-host interactions. Medical research topics of interest include but are not limited to viral pathogenesis, epidemiology, immunology, therapies and emergence of drug-resistant variants.

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  1. Selective pressure from either the immune response or the use of nucleoside analogs in antiviral therapy could be driving the emergence of HBV mutants. Because of the overlap of the open reading frame (ORF) S for...

    Authors: Mingshun Zhang, Guohong Ge, Yonglin Yang, Xubing Cai, Qiang Fu, Jie Cai and Zuhu Huang

    Citation: Virology Journal 2013 10:292

    Content type: Research

    Published on:

  2. Majority of previous studies of pegylated interferon α-2a (PegIFNα-2a) forced on naïve chronic hepatitis B (CHB) patients, and the data of PegIFNα-2a in therapy of patients with prior exposure to nucleos(t)ide...

    Authors: Min Weng, Wei-Zheng Zeng, Xiao-Ling Wu, Yong Zhang, Ming-De Jiang, Zhao Wang, De-Jiang Zhou and Xuan He

    Citation: Virology Journal 2013 10:277

    Content type: Research

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  3. Hepatitis C virus (HCV) is a major cause of liver disease and a potential cause of substantial morbidity and mortality worldwide. The overall prevalence of HCV infection is 2%, representing 120 million people ...

    Authors: Tutik Sri Wahyuni, Lydia Tumewu, Adita Ayu Permanasari, Evhy Apriani, Myrna Adianti, Abdul Rahman, Aty Widyawaruyanti, Maria Inge Lusida, Achmad Fuad, Soetjipto, Nasronudin, Hiroyuki Fuchino, Nobuo Kawahara, Ikuo Shoji, Lin Deng, Chie Aoki…

    Citation: Virology Journal 2013 10:259

    Content type: Research

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  4. Hepatitis B virus (HBV) infection is a major global health problem. The infectious virion contains an inner “core particle”, which is made of 180 or 240 copies of core protein, alternatively known as hepatitis...

    Authors: Guangyu Xu, Chengguo Wei, Yuqi Guo, Chao Zhang, Nan Zhang and Guoqing Wang

    Citation: Virology Journal 2013 10:256

    Content type: Research

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  5. The disproportionate imbalance between the systemic manifestation of reactive oxygen species and body’s ability to detoxify the reactive intermediates is referred to as oxidative stress. Several biological pro...

    Authors: Usman Zafar Paracha, Kaneez Fatima, Mohammad Alqahtani, Adeel Chaudhary, Adel Abuzenadah, Ghazi Damanhouri and Ishtiaq Qadri

    Citation: Virology Journal 2013 10:251

    Content type: Review

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  6. Hepatitis B virus (HBV) genotype F (HBV/F) is considered to be indigenous to the Americas, but its emergence and spread in the continent remain unknown. Previously, only two HBV/F complete genome sequences fro...

    Authors: Francisco CA Mello, Oscar C Araujo, Barbara V Lago, Ana Rita C Motta-Castro, Marcia Terezinha B Moraes, Selma A Gomes, Gonzalo Bello and Natalia M Araujo

    Citation: Virology Journal 2013 10:236

    Content type: Research

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  7. Little is known about HBV-specific T-cell responses in chronic Hepatitis B patients (HBV) that are co-infected with Human immunodeficiency virus type 1 (HIV-1), especially those with normal alanine aminotransf...

    Authors: Xin Zhang, Hanqian Xing, Xia Feng, Haiping Zhang, Yi Wang and Huiping Yan

    Citation: Virology Journal 2013 10:232

    Content type: Research

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  8. It has been suggested that different hepatitis B virus (HBV) genotypes may have distinct virological characteristics that correlate with clinical outcomes during antiviral therapy and the natural course of inf...

    Authors: Lei Li, Hong Shen, Anyi Li, Zhenhua Zhang, Baoju Wang, Junzhong Wang, Xin Zheng, Jun Wu, Dongliang Yang, Mengji Lu and Jingjiao Song

    Citation: Virology Journal 2013 10:214

    Content type: Research

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  9. The prevalence of HCV infection has increased during recent years and the incidence reach 3% of the world's population, and in some countries like Egypt, may around 20%. The developments of effective and preve...

    Authors: Esmail M EL-Fakharany, Lourdes Sánchez, Hussein A Al-Mehdar and Elrashdy M Redwan

    Citation: Virology Journal 2013 10:199

    Content type: Research

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  10. To evaluate the efficacy and safety of Entecavir (ETV) plus adefovir (ADV) for chronic hepatitis B (CHB) patients after multiple nucleos(t)ide analogue (NAs) failure treatment.

    Authors: Xian-Hua Xu, Gai-Li Li, Yang Qin, Qiang Li, Fa-Qun He, Jin-Ye Li, Quan-Rong Pan and Jie-Yin Deng

    Citation: Virology Journal 2013 10:162

    Content type: Research

    Published on: