Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell. 1997;88(5):637–46.
CAS
PubMed
Google Scholar
Shyh-Chang N, Daley GQ. Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell. 2013;12(4):395–406.
PubMed
PubMed Central
Google Scholar
Zhou J, Ng SB, Chng WJ. LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells. Int J Biochem Cell Biol. 2013;45(5):973–8.
CAS
PubMed
Google Scholar
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell. 2011;147(1):81–94.
CAS
PubMed
PubMed Central
Google Scholar
Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell. 2009;139(4):693–706.
CAS
PubMed
PubMed Central
Google Scholar
Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell. 2010;39(4):493–506.
CAS
PubMed
PubMed Central
Google Scholar
Mayr F, Schütz A, Döge N, Heinemann U. The Lin28 cold-shock domain remodels pre-let-7 microRNA. Nucleic Acids Res. 2012;40(15):7492–506.
CAS
PubMed
PubMed Central
Google Scholar
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell. 2011;147(5):1080–91.
CAS
PubMed
PubMed Central
Google Scholar
Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, et al. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 2011;147(5):1066–79.
CAS
PubMed
PubMed Central
Google Scholar
Guo Y, Chen Y, Ito H, Watanabe A, Ge X, Kodama T, et al. Identification and characterization of LIN-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene. 2006;384:51–61.
CAS
PubMed
Google Scholar
Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet. 2009;41(7):843–8.
CAS
PubMed
PubMed Central
Google Scholar
Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, et al. Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One. 2010;5(8):e12445.
PubMed
PubMed Central
Google Scholar
King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN, et al. LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. Oncogene. 2011;30(40):4185–93.
CAS
PubMed
PubMed Central
Google Scholar
Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, et al. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS One. 2011;6(4):e18064.
CAS
PubMed
PubMed Central
Google Scholar
Hamano R, Miyata H, Yamasaki M, Sugimura K, Tanaka K, Kurokawa Y, et al. High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer. Br J Cancer. 2012;106(8):1415–23.
CAS
PubMed
PubMed Central
Google Scholar
King CE, Cuatrecasas M, Castells A, Sepulveda AR, Lee JS, Rustgi AK. LIN28B promotes colon cancer progression and metastasis. Cancer Res. 2011;71(12):4260–8.
CAS
PubMed
PubMed Central
Google Scholar
Deng W, Zhang X, Ma Z, Lin Y, Lu M. MicroRNA-125b-5p mediates post-transcriptional regulation of hepatitis B virus replication via the LIN28B/let-7 axis. RNA Biol. 2017;14(10):1389–98.
PubMed
PubMed Central
Google Scholar
Wang YC, Chen YL, Yuan RH, Pan HW, Yang WC, Hsu HC, et al. Lin-28B expression promotes transformation and invasion in human hepatocellular carcinoma. Carcinogenesis. 2010;31(9):1516–22.
CAS
PubMed
Google Scholar
Wu G, Yu F, Xiao Z, Xu K, Xu J, Tang W, et al. Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. Br J Cancer. 2011;105(1):146–53.
CAS
PubMed
PubMed Central
Google Scholar
Wu G, Huang P, Ju X, Li Z, Wang Y. Lin28B over-expression mediates the repression of let-7 by hepatitis B virus X protein in hepatoma cells. Int J Clin Exp Med. 2015;8(9):15108–16.
CAS
PubMed
PubMed Central
Google Scholar
You X, Liu F, Zhang T, Lv N, Liu Q, Shan C, et al. Hepatitis B virus X protein upregulates Lin28A/Lin28B through Sp-1/c-Myc to enhance the proliferation of hepatoma cells. Oncogene. 2014;33(4):449–60.
PubMed
Google Scholar
Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L. Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma. J Cancer. 2019;10(24):6074–87.
CAS
PubMed
PubMed Central
Google Scholar
Liang L, Wong CM, Ying Q, Fan DN, Huang S, Ding J, et al. MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2. Hepatology. 2010;52(5):1731–40.
CAS
PubMed
Google Scholar
Cheng SW, Tsai HW, Lin YJ, Cheng PN, Chang YC, Yen CJ, et al. Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma. PLoS One. 2013;8(11):e80053.
PubMed
PubMed Central
Google Scholar
Ye Y, Madison B, Wu X, Rustgi AK. A LIN28B polymorphism predicts for colon cancer survival. Cancer Biol Ther. 2012;13(14):1390–5.
CAS
PubMed
PubMed Central
Google Scholar
Du W, Cheng J, Ding H, Jiang Z, Guo Y, Yuan H. A rapid method for simultaneous multi-gene mutation screening in children with nonsyndromic hearing loss. Genomics. 2014;104(4):264–70.
CAS
PubMed
Google Scholar
Sulem P, Gudbjartsson DF, Rafnar T, Holm H, Olafsdottir EJ, Olafsdottir GH, et al. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet. 2009;41(6):734–8.
CAS
PubMed
Google Scholar
Lu L, Katsaros D, Mayne ST, Risch HA, Benedetto C, Canuto EM, et al. Functional study of risk loci of stem cell-associated gene lin-28B and associations with disease survival outcomes in epithelial ovarian cancer. Carcinogenesis. 2012;33(11):2119–25.
CAS
PubMed
Google Scholar
Wen J, Liu H, Wang Q, Liu Z, Li Y, Xiong H, et al. Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. Eur J Cancer. 2014;50(10):1706–16.
CAS
PubMed
PubMed Central
Google Scholar
Park SW, Lee ST, Sohn YB, Cho SY, Kim SH, Kim SJ, et al. LIN28B polymorphisms are associated with central precocious puberty and early puberty in girls. Korean J Pediatr. 2012;55(10):388–92.
CAS
PubMed
PubMed Central
Google Scholar
Coignet MV, Zirpoli GR, Roberts MR, Khoury T, Bandera EV, Zhu Q, et al. Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: the Women's circle of health study. PLoS One. 2017;12(10):e0187205.
PubMed
PubMed Central
Google Scholar
Chen B, Xie F, Tang C, Ma G, Wei L, Chen Z. Study of five pubertal transition-related gene polymorphisms as risk factors for premature coronary artery disease in a Chinese Han population. PLoS One. 2015;10(8):e0136496.
PubMed
PubMed Central
Google Scholar
Widén E, Ripatti S, Cousminer DL, Surakka I, Lappalainen T, Järvelin MR, et al. Distinct variants at LIN28B influence growth in height from birth to adulthood. Am J Hum Genet. 2010;86(5):773–82.
PubMed
PubMed Central
Google Scholar
Carty CL, Spencer KL, Setiawan VW, Fernandez-Rhodes L, Malinowski J, Buyske S, et al. Replication of genetic loci for ages at menarche and menopause in the multi-ethnic population architecture using genomics and epidemiology (PAGE) study. Hum Reprod. 2013;28(6):1695–706.
PubMed
PubMed Central
Google Scholar
Hu Z, Chen R, Cai C. Association of genetic polymorphisms around the LIN28B gene and idiopathic central precocious puberty risks among Chinese girls. Pediatr Res. 2016;80(4):521–5.
CAS
PubMed
Google Scholar
Busch AS, Hagen CP, Assens M, Main KM, Almstrup K, Juul A. Differential impact of genetic loci on age at Thelarche and menarche in healthy girls. J Clin Endocrinol Metab. 2018;103(1):228–34.
PubMed
Google Scholar
Vrieze SI, McGue M, Miller MB, Legrand LN, Schork NJ, Iacono WG. An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design. PLoS Genet. 2011;7(12):e1002413.
CAS
PubMed
PubMed Central
Google Scholar
Leinonen JT, Surakka I, Havulinna AS, Kettunen J, Luoto R, Salomaa V, et al. Association of LIN28B with adult adiposity-related traits in females. PLoS One. 2012;7(11):e48785.
CAS
PubMed
PubMed Central
Google Scholar
Perry JR, Stolk L, Franceschini N, Lunetta KL, Zhai G, McArdle PF, et al. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet. 2009;41(6):648–50.
CAS
PubMed
PubMed Central
Google Scholar
Carroll J, Saxena R, Welt CK. Environmental and genetic factors influence age at menarche in women with polycystic ovary syndrome. J Pediatr Endocrinol Metab. 2012;25(5–6):459–66.
PubMed
PubMed Central
Google Scholar
Wu JF, Tsai WY, Hsu HY, Ni YH, Chen HL, Tsuei DJ, et al. Effect of puberty onset on spontaneous hepatitis B virus e antigen seroconversion in men. Gastroenterology. 2010;138(3):942–8.e1.
Leinonen JT, Chen YC, Pennonen J, Lehtonen L, Junna N, Tukiainen T, et al. LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels. Sci Rep. 2019;9(1):18060.
CAS
PubMed
PubMed Central
Google Scholar
Yu MW, Yang YC, Yang SY, Cheng SW, Liaw YF, Lin SM, et al. Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men. J Natl Cancer Inst. 2001;93(21):1644–51.
CAS
PubMed
Google Scholar
Yu MW, Cheng SW, Lin MW, Yang SY, Liaw YF, Chang HC, et al. Androgen-receptor gene CAG repeats, plasma testosterone levels, and risk of hepatitis B-related hepatocellular carcinoma. J Natl Cancer Inst. 2000;92(24):2023–8.
CAS
PubMed
Google Scholar
Yuan JM, Ross RK, Stanczyk FZ, Govindarajan S, Gao YT, Henderson BE, et al. A cohort study of serum testosterone and hepatocellular carcinoma in Shanghai. China Int J Cancer. 1995;63(4):491–3.
CAS
PubMed
Google Scholar