Table 2 LIN28B rs314280 genotype and allele frequencies in patients with chronic HBV infection, HBV infection resolvers and healthy controls
From: Association of LIN28B polymorphisms with chronic hepatitis B virus infection
|  | Patients (n = 515) | Resolvers (n = 97) | Controls (n = 169) | Patients vs. resolvers | Patients vs. controls | Resolvers vs. controls | ||||
|---|---|---|---|---|---|---|---|---|---|---|
P | OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | |||||
Genotype | ||||||||||
 Codominant | GG | 313 (60.8) | 49 (50.5) | 83 (49.1) | Reference |  | Reference |  | Reference |  |
GA | 170 (33.0) | 38 (39.2) | 76 (45.0) | 0.130 | 0.700 (0.441–1.113) | 0.005a | 0.593 (0.413–0.853) | 0.535 | 0.847 (0.501–1.433) | |
AA | 32 (6.2) | 10 (10.3) | 10 (5.9) | 0.074 | 0.501 (0.232–1.083) | 0.668 | 1.178 (0.401–1.797) | 0.271 | 1.694 (0.658–4.358) | |
 Dominant | GG | 313 (60.8) | 49 (50.5) | 83 (49.1) | Reference |  | Reference |  | Reference |  |
AA+GA | 202 (39.2) | 48 (49.5) | 86 (50.9) | 0.059 | 0.659 (0.426–1.018) | 0.008 | 0.623 (0.439–0.884) | 0.826 | 0.945 (0.574–1.558) | |
 Recessive | GG + GA | 483 (93.8) | 87 (89.7) | 159 (94.1) | Reference |  | Reference |  | Reference |  |
AA | 32 (6.2) | 10 (10.3) | 10 (5.9) | 0.148 | 0.576 (0.273–1.215) | 0.889 | 1.053 (0.506–2.191) | 0.196 | 1.828 (0.732–4.562) | |
 Overdominant | GG + AA | 345 (67.0) | 59 (60.8) | 93 (55.0) | Reference |  | Reference |  | Reference |  |
GA | 170 (33.0) | 38 (39.2) | 76 (45.0) | 0.240 | 0.765 (0.489–1.196) | 0.005 | 0.603 (0.423–0.859) | 0.358 | 0.788 (0.474–1.310) | |
 Additive | – | – | – | – | 0.038 | 0.705 (0.507–0.981) | 0.036 | 0.744 (0.564–0.981) | 0.709 | 0.927 (0.624–1.378) |
Allele | ||||||||||
| Â | G | 796 (77.3) | 136 (70.1) | 242 (71.6) | Reference | Â | Reference | Â | Reference | Â |
|  | A | 234 (22.7) | 58 (29.9) | 96 (28.4) | 0.031 | 0.689 (0.491–0.969) | 0.034 | 0.741 (0.561–0.978) | 0.714 | 1.075 (0.730–1.584) |