From: Association of LIN28B polymorphisms with chronic hepatitis B virus infection
 | AC (n = 91) | CH (n = 128) | LC (n = 127) | HCC (n = 169) | χ2 | P | |
---|---|---|---|---|---|---|---|
rs314277 | Genotype | Â | Â | Â | Â | Â | Â |
CC | 84 (92.3) | 124 (96.9) | 117 (92.1) | 159 (94.1) | Reference | Â | |
AC | 7 (7.7) | 4 (3.1) | 10 (7.9) | 10 (5.9) | 3.121 | 0.373 | |
AA | 0 (0) | 0 (0) | 0 (0) | 0 (0) | – | – | |
Allele | Â | Â | Â | Â | Â | Â | |
C | 175 (96.2) | 252 (98.4) | 244 (96.1) | 328 (97.0) | Reference | Â | |
A | 7 (3.8) | 4 (1.6) | 10 (3.9) | 10 (3.0) | 3.024 | 0.388 | |
rs314280 | Genotype | Â | Â | Â | Â | Â | Â |
GG | 51 (56.0) | 86 (67.2) | 74 (58.3) | 102 (60.4) | Reference | Â | |
GA | 34 (37.4) | 33 (25.8) | 45 (35.4) | 58 (34.3) | 4.203 | 0.240 | |
AA | 6 (6.6) | 9 (7.0) | 8 (6.3) | 9 (5.3) | 0.313 | 0.958 | |
Allele | Â | Â | Â | Â | Â | Â | |
G | 136 (74.7) | 205 (80.1) | 193 (76.0) | 262 (77.5) | Reference | Â | |
A | 46 (25.3) | 51 (19.9) | 61 (24.0) | 76 (22.5) | 2.072 | 0.558 | |
rs369065 | Genotype | Â | Â | Â | Â | Â | Â |
TT | 40 (44.0) | 70 (54.7) | 50 (39.4) | 79 (46.7) | Reference | Â | |
TC | 37 (40.7) | 37 (28.9) | 62 (48.8) | 74 (43.8) | 9.912 | 0.019 | |
CC | 14 (15.4) | 21 (16.4) | 15 (11.8) | 16 (9.5) | 2.065 | 0.559 | |
Allele | Â | Â | Â | Â | Â | Â | |
T | 117 (64.3) | 177 (69.1) | 162 (63.8) | 232 (68.6) | Reference | Â | |
C | 65 (35.7) | 79 (30.9) | 92 (36.2) | 106 (31.4) | 2.711 | 0.438 | |
rs7759938 | Genotype | Â | Â | Â | Â | Â | Â |
TT | 53 (58.2) | 88 (68.8) | 72 (56.7) | 104 (61.5) | Reference | Â | |
TC | 31 (37.1) | 32 (25.0) | 46 (36.2) | 57 (33.7) | 4.586 | 0.205 | |
CC | 7 (7.7) | 8 (6.3) | 9 (7.1) | 8 (4.7) | 1.449 | 0.694 | |
Allele | Â | Â | Â | Â | Â | Â | |
T | 137 (75.3) | 208 (81.2) | 190 (74.8) | 265 (78.4) | Reference | Â | |
C | 45 (24.7) | 48 (18.8) | 64 (25.2) | 73 (21.6) | 3.802 | 0.284 |