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  1. Although the sequence of the human cytomegalovirus (HCMV) genome is generally conserved among unrelated clinical strains, some open reading frames (ORFs) are highly variable. UL146 and UL147, which encode CXC ...

    Authors: Nell S Lurain, Andrea M Fox, Heather M Lichy, Sangeeta M Bhorade, Carl F Ware, Diana D Huang, Sau-Ping Kwan, Edward R Garrity and Sunwen Chou
    Citation: Virology Journal 2006 3:4
  2. Human polyomavirus JC (JCV), the etiological agent of the disease progressive multifocal leukoencephalopathy (PML) affects immunocompromised patients particularly patients with AIDS. In vitro studies of JCV infec...

    Authors: Moti L Chapagain, Taylor Nguyen, Thomas Bui, Saguna Verma and Vivek R Nerurkar
    Citation: Virology Journal 2006 3:3
  3. Encephalitis caused by flaviviruses, Japanese encephalitis virus (JEV) and West Nile virus (WNV) is responsible for significant morbidity and mortality in many endemic countries. Dengue-2 (Den-2) virus is a re...

    Authors: Rangaiah S Jayakeerthi, Raghava V Potula, S Srinivasan and S Badrinath
    Citation: Virology Journal 2006 3:2
  4. The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses. In this report, we sought to determine whe...

    Authors: Ziying Han and Ronald N Harty
    Citation: Virology Journal 2005 2:92
  5. Molecular epidemiological investigation of measles outbreaks can document the interruption of endemic measles transmission and is useful for establishing and clarifying epidemiological links between cases in g...

    Authors: Michaela A Riddell, Jennifer S Rota and Paul A Rota
    Citation: Virology Journal 2005 2:87
  6. Poliovirus protein 3CDpro possesses both proteinase and RNA binding activities, which are located in the 3Cpro domain of the protein. The RNA polymerase (3Dpol) domain of 3CDpro modulates these activities of the ...

    Authors: David Franco, Harsh B Pathak, Craig E Cameron, Bart Rombaut, Eckard Wimmer and Aniko V Paul
    Citation: Virology Journal 2005 2:86
  7. Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants and young children. Although several experimental RSV vaccines are under investigation, immuno therapy is th...

    Authors: Edyta Zielinska, Daiqing Liu, Hong-Yin Wu, Jorge Quiroz, Ruth Rappaport and Da-Ping Yang
    Citation: Virology Journal 2005 2:84
  8. Inactive carriers forms the largest group in chronic HBV infected patients. Around 300 million people are inactive carriers The inactive HBsAg carrier state is diagnosed by absence of HBeAg and presence of ant...

    Authors: Sanjeev Kumar Sharma, Nitin Saini and Yogesh Chwla
    Citation: Virology Journal 2005 2:82
  9. Hepatitis C virus (HCV) infection is of growing concern in public health with around 350 million chronically infected individuals worldwide. Although the IFN-α/rivabirin is the only approved therapy with 10–30...

    Authors: Carmen E Gómez, Andrée Marie Vandermeeren, María Angel García, Elena Domingo-Gil and Mariano Esteban
    Citation: Virology Journal 2005 2:81
  10. In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8) [1]. This novel herpesvirus has and continues to present challenges to define its scope of i...

    Authors: Daniel C Edelman
    Citation: Virology Journal 2005 2:78
  11. Acute retinal necrosis is a sight-threatening disease caused by the group of herpesviruses. The aim of this paper is to report a case of acute retinal necrosis following ocular trauma in a patient initially tr...

    Authors: Petra Svozílková, Eva Říhová, Pavel Diblík, Pavel Kuthan, Zdeněk Kovařík and Bohdana Kalvodová
    Citation: Virology Journal 2005 2:77
  12. Infectious salmon anaemia (ISA) is a highly fatal viral disease affecting marine-farmed Atlantic salmon which is caused by ISA virus (ISAV), a fish orthomyxovirus that has recently been assigned to the new genus

    Authors: Molly JT Kibenge, Khalid Munir and Frederick SB Kibenge
    Citation: Virology Journal 2005 2:75
  13. The entry of the SARS coronavirus (SCV) into cells is initiated by binding of its spike envelope glycoprotein (S) to a receptor, ACE2. We and others identified the receptor-binding domain (RBD) by using S frag...

    Authors: Samitabh Chakraborti, Ponraj Prabakaran, Xiaodong Xiao and Dimiter S Dimitrov
    Citation: Virology Journal 2005 2:73
  14. Previous studies presented the quasispecies spectrum of the envelope region of dengue virus type 3 (DENV-3) from either clinical specimens or field-caught mosquitoes. However, the extent of sequence variation ...

    Authors: Day-Yu Chao, Chwan-Chuen King, Wei-Kung Wang, Wei-June Chen, Hui-Lin Wu and Gwong-Jen J Chang
    Citation: Virology Journal 2005 2:72
  15. White spot syndrome virus (WSSV) is an important pathogen of the penaeid shrimp with high mortalities. In previous reports, Orf427 of WSSV is characterized as one of the three major latency-associated genes of WS...

    Authors: Liqun Lu, Hai Wang, Ivanus Manopo, Li Yu and Jimmy Kwang
    Citation: Virology Journal 2005 2:71
  16. Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol

    Authors: Richard Sallie
    Citation: Virology Journal 2005 2:70
  17. Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

    Authors: Martin J Vincent, Eric Bergeron, Suzanne Benjannet, Bobbie R Erickson, Pierre E Rollin, Thomas G Ksiazek, Nabil G Seidah and Stuart T Nichol
    Citation: Virology Journal 2005 2:69
  18. Approximately 25% of hemophiliacs that were frequently exposed to blood clotting factor concentrates (CFCs) contaminated with human immunodeficiency virus (HIV) are presently HIV seronegative. In this study, w...

    Authors: Scott A Tenenbaum, Cindy A Morris, Steve S Alexander, Harris E McFerrin, Robert F Garry and Cindy A Leissinger
    Citation: Virology Journal 2005 2:65
  19. The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million...

    Authors: Elodie Ghedin and Jean-Michel Claverie
    Citation: Virology Journal 2005 2:62
  20. Herpes Simplex Virus (HSV) Genital Ulcer Disease (GUD) is an important public health problem, whose interaction with HIV results in mutually enhancing epidemics. Conventional methods for detecting HSV tend to ...

    Authors: Esther AN Aryee, Robin L Bailey, Angels Natividad-Sancho, Steve Kaye and Martin J Holland
    Citation: Virology Journal 2005 2:61
  21. Around 400 million people worldwide are chronically infected with Hepatitis B virus (HBV). An estimated 10% of these chronic patients develop progressive liver damage including cirrhosis and Hepatocellular Car...

    Authors: Bernal León, Lizeth Taylor, Minor Vargas, Ronald B Luftig, Federico Albertazzi, Libia Herrero and Kirsten Visona
    Citation: Virology Journal 2005 2:60
  22. Molecular epidemiologic studies have made significant contributions to measles surveillance activities by helping to identify source and transmission pathways of the virus. This report describes the genetic ch...

    Authors: Gulay Korukluoglu, Stephanie Liffick, Dalya Guris, Fumio Kobune, Paul A Rota, William J Bellini, Ali Ceylan and Meliksah Ertem
    Citation: Virology Journal 2005 2:58
  23. The recent emergence of four new members of the paramyxovirus family has heightened the awareness of and re-energized research on new and emerging diseases. In particular, the high mortality and person to pers...

    Authors: Katharine N Bossart, Bruce A Mungall, Gary Crameri, Lin-Fa Wang, Bryan T Eaton and Christopher C Broder
    Citation: Virology Journal 2005 2:57
  24. Human cytomegalovirus UL114 encodes a uracil-DNA glycosylase homolog that is highly conserved in all characterized herpesviruses that infect mammals. Previous studies demonstrated that the deletion of this noness...

    Authors: Mark N Prichard, Heather Lawlor, Gregory M Duke, Chengjun Mo, Zhaoti Wang, Melissa Dixon, George Kemble and Earl R Kern
    Citation: Virology Journal 2005 2:55
  25. Human respiratory syncytial virus (HRSV) is an important respiratory pathogen primarily affecting infants, young children, transplant recipients and the elderly. The F protein is the only virion envelope prote...

    Authors: Patrick J Branigan, Changbao Liu, Nicole D Day, Lester L Gutshall, Robert T Sarisky and Alfred M Del Vecchio
    Citation: Virology Journal 2005 2:54
  26. Giant double-stranded DNA viruses (such as record breaking Acanthamoeba polyphaga Mimivirus), with particle sizes of 0.2 to 0.6 μm, genomes of 300 kbp to 1.200 kbp, and commensurate complex gene contents, constit...

    Authors: Jean-Michel Claverie
    Citation: Virology Journal 2005 2:52
  27. A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained f...

    Authors: Timothy HP Tan, Timothy Barkham, Burtram C Fielding, Chih-Fong Chou, Shuo Shen, Seng Gee Lim, Wanjin Hong and Yee-Joo Tan
    Citation: Virology Journal 2005 2:51
  28. High-risk Human Papillomavirus (HPV) is the etiological agent associated with the majority of anogenital cancers. The primary HPV oncogenes, E6 and E7, undergo a complex splicing program resulting in protein p...

    Authors: Kulthida Vaeteewoottacharn, Siriphatr Chamutpong, Mathurose Ponglikitmongkol and Peter C Angeletti
    Citation: Virology Journal 2005 2:50
  29. The palindromic termini of parvoviruses have proven to play an essential role as origins of replication at different stages during the replication of their viral genome. Sequences from the left-end telomere of...

    Authors: Nanette Diffoot-Carlo, Lisandra Vélez-Pérez and Idaris de Jesús-Maldonado
    Citation: Virology Journal 2005 2:47