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  1. Transjugular intrahepatic portosystemic shunt (TIPS) procedure has played a vital role in management of portal hypertension. Thus, we aimed to investigate the natural history, long-term clinical outcome, predi...

    Authors: Dengke Teng, Hao Zuo, Lin Liu, Jinghui Dong and Lei Ding

    Citation: Virology Journal 2018 15:151

    Content type: Research

    Published on:

  2. Human adenoviruses are common causes of community-acquired respiratory tract and enteric infections. Severe disseminated infections with high mortality rates may be seen in immunocompromised individuals. An ac...

    Authors: Samson S. Y. Wong, Cyril C. Y. Yip, Siddharth Sridhar, Kit-Hang Leung, Andrew K. W. Cheng, Ami M. Y. Fung, Ho-Yin Lam, Kwok-Hung Chan, Jasper F. W. Chan, Vincent C. C. Cheng, Bone S. F. Tang and Kwok-Yung Yuen

    Citation: Virology Journal 2018 15:149

    Content type: Methodology

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  3. A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of a...

    Authors: Huanan Wang, Feng Cong, Jianchi Guan, Li Xiao, Yujun Zhu, Yuexiao Lian, Ren Huang, Meili Chen and Pengju Guo

    Citation: Virology Journal 2018 15:146

    Content type: Methodology

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  4. Torquetenovirus (TTV) belongs to Anelloviridae family, infects nearly all people indefinitely without causing overt disease establishing a fine and successful interaction with the host. Increasing evidence have s...

    Authors: Francesco Martelli, Lisa Macera, Pietro Giorgio Spezia, Chiara Medici, Mauro Pistello, Daniele Guasti, Paolo Romagnoli, Fabrizio Maggi and Simone Giannecchini

    Citation: Virology Journal 2018 15:145

    Content type: Research

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  5. We evaluated the frequency of naturally occurring resistance associated substitutions (RASs) and their characteristic of polymorphic or non-polymorphic amino acid change to direct acting antivirals (DAAs) in N...

    Authors: Sabrina Bagaglio, Caterina Uberti-Foppa, Alessandro Olgiati, Emanuela Messina, Hamid Hasson, Camilla Ferri and Giulia Morsica

    Citation: Virology Journal 2018 15:144

    Content type: Research

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  6. Antiretrovirals have been available in Ghana since 2003 for HIV-1 positive pregnant women for prevention of mother-to-child transmission (PMTCT). Suboptimal responses to treatment observed post-PMTCT intervent...

    Authors: Alexander Martin-Odoom, Charles Addoquaye Brown, John Kofi Odoom, Evelyn Yayra Bonney, Nana Afia Asante Ntim, Elena Delgado, Margaret Lartey, Kwamena William Sagoe, Theophilus Adiku and William Kwabena Ampofo

    Citation: Virology Journal 2018 15:143

    Content type: Research

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  7. Tembusu virus is a newly emerging flavivirus that caused egg-drop syndrome in ducks in China. TMUV envelope protein is a major structural protein locates at the surface of tembusu virus particle. During tembus...

    Authors: Dongmin Zhao, Kaikai Han, Xinmei Huang, Lijiao Zhang, Huili Wang, Na Liu, Yujie Tian, Qingtao Liu, Jing Yang, Yuzhuo Liu and Yin Li

    Citation: Virology Journal 2018 15:142

    Content type: Research

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  8. The non-translated regions at the genome ends of RNA viruses serve diverse functions and can exhibit various levels of nucleotide (nt) heterogeneity. However, the extent of nt heterogeneity at the extreme term...

    Authors: Angel Y. S. Chen, Shizu Watanabe, Raymond Yokomi and James C. K. Ng

    Citation: Virology Journal 2018 15:141

    Content type: Research

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  9. Duck Tembusu virus (DTMUV), a pathogenic flavivirus, emerged in China since 2010 and causing huge economic loss in the Chinese poultry industry. Although several vaccines have been reported to control DTMUV di...

    Authors: Jingyu Tang, Zhuangli Bi, Mingyang Ding, Dongdong Yin, Jie Zhu, Li Zhang, Qiuhong Miao, Yingqi Zhu, Guijun Wang and Guangqing Liu

    Citation: Virology Journal 2018 15:140

    Content type: Research

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  10. Tobacco curly shoot virus (TbCSV) is a monopartite begomovirus associated with betasatellite (Tobacco curly shoot betasatellite, TbCSB), which causes serious leaf curl disease on tomato and tobacco in China. It i...

    Authors: Ke Li, Gentu Wu, Mingjun Li, Mingge Ma, Jiang Du, Miao Sun, Xianchao Sun and Ling Qing

    Citation: Virology Journal 2018 15:138

    Content type: Research

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  11. Ad-HBV is a product (T101) aiming to treat chronic HBV firstly developed by Transgene S.A., France then by Transgene Tasly (Tianjin) Biopharmaceutical Co., Ltd., Tianjin, China in China.

    Authors: Xuefeng Zhang, Jing Wang, Jing Lu, Rongrong Li and Shuli Zhao

    Citation: Virology Journal 2018 15:137

    Content type: Correction

    Published on:

    The original article was published in Virology Journal 2018 15:111

  12. JC polyomavirus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunosuppressed patients. PML usually has a poor prog...

    Authors: Hitomi Kinoshita, Kazuo Nakamichi, Chang-Kweng Lim, Mutsuyo Takayama-Ito, Lixin Wang, Itoe Iizuka, Ichiro Kurane and Masayuki Saijo

    Citation: Virology Journal 2018 15:136

    Content type: Research

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    The Correction to this article has been published in Virology Journal 2018 15:154

  13. Currently, no FDA-approved vaccines or treatments are available for Ebola virus disease (EVD), and therapy remains largely supportive. Ebola virus (EBOV) has broad tissue tropism and can infect a variety of ce...

    Authors: Manasi Tamhankar, Dawn M. Gerhardt, Richard S. Bennett, Nicole Murphy, Peter B. Jahrling and Jean L. Patterson

    Citation: Virology Journal 2018 15:135

    Content type: Research

    Published on:

  14. Geminiviruses cause major losses to several economically important crops. Pedilanthus leaf curl virus (PeLCV) is a pathogenic geminivirus that appeared in the last decade and is continuously increasing its host r...

    Authors: Sara Shakir, Muhammad Shah Nawaz-ul-Rehman, Muhammad Mubin and Zulfiqar Ali

    Citation: Virology Journal 2018 15:134

    Content type: Research

    Published on:

  15. Porcine epidemic diarrhea virus (PEDV) is emerging as a pathogenic coronavirus that causes a huge economic burden to the swine industry. Interaction of the viral spike (S) surface glycoprotein with the host ce...

    Authors: Lang Gong, Ying Lin, Jianru Qin, Qianniu Li, Chunyi Xue and Yongchang Cao

    Citation: Virology Journal 2018 15:133

    Content type: Research

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  16. Viral infection activates innate immune pathways and interferons (IFNs) play a pivotal role in the outcome of a viral infection. Ubiquitin modifications of host and viral proteins significantly influence the p...

    Authors: Tingting Feng, Lei Deng, Xiaochuan Lu, Wen Pan, Qihan Wu and Jianfeng Dai

    Citation: Virology Journal 2018 15:132

    Content type: Research

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  17. Dengue is the most common mosquito-borne infection worldwide and a serious threat to global public health. Sporadic dengue virus serotype 2 (DENV-2) imported cases from Myanmar have been documented almost ever...

    Authors: Zhaoping Zeng, Jiandong Shi, Xiaofang Guo, Ling Mo, Ningzhu Hu, Jing Sun, Meini Wu, Hongning Zhou and Yunzhang Hu

    Citation: Virology Journal 2018 15:131

    Content type: Research

    Published on:

  18. Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus within the family Togaviridae, which has attracted global attention due to its recent re-emergence. In one of our previous studies, we successfully i...

    Authors: Xiaomin Zhang, Yalan Huang, Miao Wang, Fan Yang, Chunli Wu, Dana Huang, Linghong Xiong, Chengsong Wan, Jinquan Cheng and Renli Zhang

    Citation: Virology Journal 2018 15:130

    Content type: Research

    Published on:

  19. Epidemiological studies have established human papillomavirus (HPV) infection as the central cause of invasive cervical cancer (ICC) and its precursor lesions. HIV is associated with a higher prevalence and pe...

    Authors: Sonia Menon, Rodolfo Rossi, Mbabazi Kariisa and Steven Callens

    Citation: Virology Journal 2018 15:129

    Content type: Commentary

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  20. Cassava brown streak disease (CBSD) has a viral aetiology and is caused by viruses belonging to the genus Ipomovirus (family Potyviridae), Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus ...

    Authors: Esperance Munganyinka, Paolo Margaria, Samar Sheat, Elijah M. Ateka, Fred Tairo, Joseph Ndunguru and Stephan Winter

    Citation: Virology Journal 2018 15:128

    Content type: Methodology

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  21. Pear ring rot, caused by Botryosphaeria species, is responsible for substantial economic losses by causing severe recession of pear tree growth in China. Mycovirus-mediated hypovirulence in plant pathogenic fungi...

    Authors: Lihua Wang, Hui Luo, Wangcheng Hu, Yuekun Yang, Ni Hong, Guoping Wang, Aiming Wang and Liping Wang

    Citation: Virology Journal 2018 15:126

    Content type: Research

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  22. Bocaviruses have been reported to cause respiratory tract infection and gastroenteritis in most animal species. In cats, different genotype bocaviruses have been identified in USA, Japan, Hong Kong and Portuga...

    Authors: Shushuai Yi, Jiangting Niu, Hualei Wang, Guoying Dong, Yanli Zhao, Hao Dong, Yanbing Guo, Kai Wang and Guixue Hu

    Citation: Virology Journal 2018 15:125

    Content type: Research

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  23. Antimicrobial peptides (AMPs) are primarily known for their innate immune defense against invading microorganisms, including viruses. In addition, recent research has suggested their modulatory activity in imm...

    Authors: Ju Kim, Ye Lin Yang, Sun-Hee Jang and Yong-Suk Jang

    Citation: Virology Journal 2018 15:124

    Content type: Research

    Published on:

  24. Pneumonia is a serious public health issue and is concerned around the world. This study is to investigate the association between viral load in children with human adenovirus (HAdV) pneumonia and disease seve...

    Authors: Leyun Xie, Bing Zhang, Jieying Zhou, Han Huang, Saizhen Zeng, Qin Liu, Zhiping Xie, Hanchun Gao, Zhaojun Duan and Lili Zhong

    Citation: Virology Journal 2018 15:123

    Content type: Research

    Published on:

  25. Lokern virus (LOKV) is a poorly characterized arthropod-borne virus belonging to the genus Orthobunyavirus (family Peribunyaviridae). All viruses in this genus have tripartite, single-stranded, negative-sense RNA...

    Authors: Chandra S. Tangudu, Jermilia Charles and Bradley J. Blitvich

    Citation: Virology Journal 2018 15:122

    Content type: Research

    Published on:

  26. Burkina Faso is a high endemicity country for HBV infection. However, there are few data on vaccine coverage against HBV. The aim of this study was to contribute to the improvement of HBV vaccine coverage in O...

    Authors: Birama Diarra, Albert Theophane Yonli, Abdoul Karim Ouattara, Theodora Mahoukèdè Zohoncon, Lassina Traore, Christelle Nadembega, Dorcas Obiri-Yeboah, Justine Yara, Virginio Pietra, Paul Ouedraogo, Alain Bougouma, Rokia Sanogo and Jacques Simpore

    Citation: Virology Journal 2018 15:121

    Content type: Research

    Published on:

  27. The results of our previous study showed that impaired cellular energy metabolism contributes to duck enteritis virus-induced autophagy via the 5`-adenosine monophosphate-activated protein kinase (AMPK)/tubero...

    Authors: Haichang Yin, Lili Zhao, Yiping Wang, Siqi Li, Hong Huo and Hongyan Chen

    Citation: Virology Journal 2018 15:120

    Content type: Research

    Published on:

  28. The alphaherpesvirus virion host shutoff (vhs) gene, UL41, can induce degradation of host mRNAs and shut off host protein synthesis. The roles of vhs in HSV-1 and HSV-2 have been studied extensively in previou...

    Authors: Chao Ye, Jing Chen, Tao Wang, Jingjing Xu, Hao Zheng, Jiqiang Wu, Guoxin Li, Zhiqing Yu, Wu Tong, Xuefei Cheng, Shasha Zhou and Guangzhi Tong

    Citation: Virology Journal 2018 15:119

    Content type: Research

    Published on:

  29. Canine distemper (CD) is a highly contagious, systemic, viral disease of dogs seen worldwide. Despite intensive vaccination in developed countries, recent reports suggest both the re-emergence and increased ac...

    Authors: Eman Anis, Teresa K. Newell, Neil Dyer and Rebecca P. Wilkes

    Citation: Virology Journal 2018 15:118

    Content type: Research

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  30. Previous work indicated that an ultrashort pulse (USP) 425 nm laser is capable of inactivating murine norovirus (MNV: Virol. J. 11:20), perhaps via an impulsive stimulated Raman scattering (ISRS) mechanism, an...

    Authors: David Kingsley, Robinson Kuis, Rafael Perez, Isaac Basaldua, Paul Burkins, Aristides Marcano and Anthony Johnson

    Citation: Virology Journal 2018 15:117

    Content type: Research

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  31. Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), which is sometimes associated with severe central nervous system disease in children. There is currently no s...

    Authors: Chenguang Yao, Caili Xi, Kanghong Hu, Wa Gao, Xiaofeng Cai, Jinlan Qin, Shiyun Lv, Canghao Du and Yanhong Wei

    Citation: Virology Journal 2018 15:116

    Content type: Research

    Published on:

  32. Bovine viral diarrhea virus (BVDV) causes significant economic losses worldwide in the cattle industry through decrease in productive performance and immunosuppression of animals in herds. Recent studies condu...

    Authors: Kyung-Hyun Lee, Du-Gyeong Han, Suhee Kim, Eun-Jin Choi and Kyoung-Seong Choi

    Citation: Virology Journal 2018 15:115

    Content type: Research

    Published on:

  33. Reovirus type-3 infections cause severe pathologies in young mice and thus influence animal experiments in many ways. Therefore, the Federation of Laboratory Animal Science Associations (FELASA) recommends an ...

    Authors: Felix Fingas, Daniela Volke, Petra Bielefeldt, Rayk Hassert and Ralf Hoffmann

    Citation: Virology Journal 2018 15:114

    Content type: Research

    Published on:

  34. Dengue virus (DENV) infection caused by international visitors has become a public health concern in China. Although sporadic imported cases of DENV have been documented in Yunnan, China since 2000, a complete...

    Authors: Ling Mo, Jiandong Shi, Xiaofang Guo, Zhaoping Zeng, Ningzhu Hu, Jing Sun, Meini Wu, Hongning Zhou and Yunzhang Hu

    Citation: Virology Journal 2018 15:113

    Content type: Research

    Published on:

  35. Chikungunya (CHIKV) virus is an important mosquito-borne virus causing outbreaks of acute febrile illness with arthropathy. The detection of specific antibodies against CHIKV is used for diagnosis after the ac...

    Authors: Marcílio Jorge Fumagalli, William Marciel de Souza, Danillo Lucas Alves Espósito, Angélica Silva, Marilia Farignoli Romeiro, Edson Zangiacomi Martinez, Benedito Antônio Lopes da Fonseca and Luiz Tadeu Moraes Figueiredo

    Citation: Virology Journal 2018 15:112

    Content type: Methodology

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  36. A new promising therapeutic approach has emerged for patients chronically infected by the hepatitis B virus (HBV) with the development of a non-replicative adenovirus vector vaccine candidate (Ad-HBV). The vac...

    Authors: Xuefeng Zhang, Jing Wang, Jing Lu, Rongrong Li and Shuli Zhao

    Citation: Virology Journal 2018 15:111

    Content type: Research

    Published on:

    The Correction to this article has been published in Virology Journal 2018 15:137

  37. Echoviruses, a serotype of enteroviruses, infect millions of people globally and there is no specific drug treatment or vaccine available for its management. The screening of medicinal plants used locally for ...

    Authors: Omonike O. Ogbole, Toluwanimi E. Akinleye, Peter A. Segun, Temitope C. Faleye and Adekunle J. Adeniji

    Citation: Virology Journal 2018 15:110

    Content type: Research

    Published on:

  38. Small hydrophobic (SH) gene is one of the mostly diverse genomic regions of human respiratory syncytial virus (HRSV). Its coding region constitutes less than 50% of the complete gene length, enabling SH gene t...

    Authors: Jelena Ivancic-Jelecki, Anamarija Slovic, Sunčanica Ljubin-Sternak, Gordana Mlinarić Galinović and Dubravko Forcic

    Citation: Virology Journal 2018 15:109

    Content type: Research

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  39. Serologic detection of Zika virus (ZIKV) infections is challenging because of antigenic similarities among flaviviruses.

    Authors: Mariana Kikuti, Laura B. Tauro, Patrícia S. S. Moreira, Gúbio S. Campos, Igor A. D. Paploski, Scott C. Weaver, Mitermayer G. Reis, Uriel Kitron and Guilherme S. Ribeiro

    Citation: Virology Journal 2018 15:108

    Content type: Research

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  40. A treatment of HCV infection depends on the genotype and sub-genotype. Therefore, accurate HCV genotyping is critical for selecting the appropriate treatment regimen.

    Authors: Shrikant Dasharath Warkad, Satish Balasaheb Nimse, Keum-Soo Song, Wasun Chantratita, Viroj Pongthanapisith, Laxman Uddhav Nawale and Taisun Kim

    Citation: Virology Journal 2018 15:107

    Content type: Research

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  41. Rice stripe virus (RSV) belongs to the genus Tenuivirus. It is transmitted by small brown planthoppers in a persistent and circulative-propagative manner and causes rice stripe disease (RSD). The NS3 protein of R...

    Authors: Gentu Wu, Guixian Zheng, Qiao Hu, Mingge Ma, Mingjun Li, Xianchao Sun, Fei Yan and Ling Qing

    Citation: Virology Journal 2018 15:105

    Content type: Research

    Published on:

  42. Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats, aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambi...

    Authors: Flora Hoarau, Gildas Le Minter, Léa Joffrin, M. Corrie Schoeman, Erwan Lagadec, Beza Ramasindrazana, Andréa Dos Santos, Steven M. Goodman, Eduardo S. Gudo, Patrick Mavingui and Camille Lebarbenchon

    Citation: Virology Journal 2018 15:104

    Content type: Short report

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  43. Canine parvovirus (CPV) has been considered to be an important pathogen, which can cause acute infectious disease in canids. Although current vaccines are effective in preventing CPV infection, safety problems...

    Authors: Liangliang Nan, Yunchao Liu, Pengchao Ji, Hua Feng, Chen Chen, Juan Wang, Dongmin Liu, Yinglei Cui, Yanwei Wang, Yafei Li, Enmin Zhou and Gaiping Zhang

    Citation: Virology Journal 2018 15:103

    Content type: Short report

    Published on:

  44. Pig diarrhea causes high mortality and large economic losses in the swine industry. Transmissible gastroenteritis virus (TGEV) causes pig diarrhea, with 100% mortality in piglets less than 2 weeks old. No inve...

    Authors: Lu Xia, Yunhan Yang, Jialu Wang, Yuchao Jing and Qian Yang

    Citation: Virology Journal 2018 15:102

    Content type: Research

    Published on:

  45. Chinese woodchucks (M. himalayana) were recently found to be susceptible to woodchuck hepatitis virus (WHV) infection. In this study, we aimed to determine the susceptibility to WHV infection of M. himalayana fro...

    Authors: Bin Zhu, Zhenni Zhu, Junzhong Wang, Shunmei Huang, Fanghui Li, Lu Wang, Yanan Liu, Qi Yan, Shunchang Zhou, Mengji Lu, Dongliang Yang and Baoju Wang

    Citation: Virology Journal 2018 15:101

    Content type: Research

    Published on: