Fedson DS. Confronting an influenza pandemic with inexpensive generic agents: can it be done? Lancet Inf Dis. 2008;8:571–6.
Article
CAS
Google Scholar
Herold S, Ludwig S, Pleschka S, Wolff T. Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury. J Leukoc Biol. 2012;92:75–82.
Article
CAS
PubMed
Google Scholar
Horby P, Nguyen NY, Dunstan SJ, Baillie JK. The role of host genetics in susceptibility to influenza: a systematic review. PLoS ONE. 2012;7:e33180.
Article
CAS
PubMed
PubMed Central
Google Scholar
Aditama, T.Y., Samaan, G., Kusriastuti, R., Purba, W.H., Misriyah, Santoso, H., Bratasena, A., Maruf, A., Sariwati, E., Setiawaty, V., et al. Risk factors for cluster outbreaks of Avian influenza A H5N1 infection, Indonesia. Clinical Infectious Diseases, 2011. 53: 1237–1244.
Horby P, Sudoyo H, Viprakasit V, Fox A, Thai PQ, Yu H, Davila S, Hibberd M, Dunstan SJ, Monteerarat Y, et al. What is the evidence of a role for host genetics in susceptibility to influenza A/H5N1? Epidemiol Infect. 2010;138:1550–8.
Article
CAS
PubMed
Google Scholar
Sedyaningsih ER, Isfandari S, Setiawaty V, Rifati L, Harun S, Purba W, Imari S, Giriputra S, Blair PJ, Putnam SD, et al. Epidemiology of cases of H5N1 virus infection in Indonesia, July 2005–June 2006. J Infect Dis. 2007;196:522–7.
Article
PubMed
Google Scholar
CDC. People at high risk of developing flu-related complications. 2017 [cited 2017].
Campbell A, Rodin R, Kropp R, Mao Y, Hong Z, Vachon J, Spika J, Pelletier L. Risk of severe outcomes among patients admitted to hospital with pandemic (H1N1) influenza. Can Med Assoc J. 2010;182:349–55.
Article
Google Scholar
Hanslik T, Boelle PY, Flahault A. Preliminary estimation of risk factors for admission to intensive care units and for death in patients infected with A(H1N1)2009 influenza virus, France, 2009–2010. PLoS Curr. 2010;5:2157–3999.
Google Scholar
Valdez R, Narayan KMV, Geiss LS, Engelgau MM. The impact of diabetes mellitus on mortality associated with pneumonia and influenza among non-hispanic black and white US adults. Am J Public Health. 1999;89:1715–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Webb SA, Pettilä V, Seppelt I, Bellomo R, Bailey M, Cooper DJ, Cretikos M, Davies AR, Finfer S, Harrigan PW, et al. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med. 2009;361:1925–34.
Article
PubMed
Google Scholar
Ribeiro, A.F., Pellini, A.C.G., Kitagawa, B.Y., Marques, D., Madalosso, G., N.F.G., d.C., Fred, J., Albernaz, R.K.M., Carvalhanas, T.R.M.P., Zanetta, D.M.T. Risk factors for death from influenza A(H1N1)pdm09, State of São Paulo, Brazil, 2009. PLoS ONE, 2015. 10: e0118772.
Horby P, Nguyen NY, Dunstan SJ, Kenneth Baillie J. An updated systematic review of the role of host genetics in susceptibility to influenza. Influ Other Respir Viruses. 2013;7:37–41.
Article
Google Scholar
Antonopoulou A, Baziaka F, Tsaganos T, Raftogiannis M, Koutoukas P, Spyridaki A, Mouktaroudi M, Kotsaki A, Savva A, Georgitsi M, et al. Role of tumor necrosis factor gene single nucleotide polymorphisms in the natural course of 2009 influenza A H1N1 virus infection. Int J Inf Dis. 2012;16:e204–8.
Article
CAS
Google Scholar
Maestri, A., Sortica, V.A., Tovo-Rodrigues, L., Santos, M.C., Barbagelata, L., Moraes, M.R., Alencar de Mello, W., Gusmão, L., Sousa, R.C.M., Emanuel Batista dos Santos, S. Siaα2–3Galβ1- receptor genetic variants are associated with influenza A(H1N1)pdm09 severity. PLoS ONE, 2015. 10: e0139681.
Zhou J, To KK, Dong H, Cheng ZS, Lau CC, Poon VK, Fan YH, Song YQ, Tse H, Chan KH, et al. A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection. J Inf Dis. 2012;206:495–503.
Article
CAS
Google Scholar
Zúñiga, J., Buendía-Roldán, I., Zhao, Y., Jiménez, L., Torres, D., Romo, J., Ramírez, G., Cruz, A., Vargas-Alarcon, G., Sheu, C.C., et al. Genetic variants associated with severe pneumonia in A/H1N1 influenza infection. Eur Respir J, 2012. 39: https://doi.org/10.1183/09031936.00020611.
Morales-García G, Falfán-Valencia R, García-Ramírez RA, Camarena Á, Ramirez-Venegas A, Castillejos-López M, Pérez-Rodríguez M, González-Bonilla C, Grajales-Muñíz C, Borja-Aburto V, et al. Pandemic influenza A/H1N1 virus infection and TNF, LTA, IL1B, IL6, IL8, and CCL polymorphisms in Mexican population: a case-control study. BMC Infect Dis. 2012;12:1–9.
Article
CAS
Google Scholar
Bailey CC, Huang IC, Kam C, Farzan M. IFITM3 limits the severity of acute influenza in mice. PLoS Pathog. 2012;8:e1002909.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan B, Weyer JL, van der Weyden L, Fikrig E, et al. IFITM proteins mediate the innate immune response to influenza A H1N1 virus, West Nile Virus and Dengue Virus. Cell. 2009;139:1243–54.
Article
PubMed
PubMed Central
Google Scholar
Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, et al. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011;7:e1001258.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lu J, Pan Q, Rong L, He W, Liu SL, Liang C. The IFITM proteins inhibit HIV-1 infection. J Virol. 2011;85:2126–37.
Article
CAS
PubMed
Google Scholar
Zhang YH, Zhao Y, Li N, Peng YC, Giannoulatou E, Jin RH, Yan HP, Wu H, Liu JH, Liu N, et al. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals. Nat Commun. 2013;4:1418.
Article
PubMed
CAS
Google Scholar
Mehrbod P, Eybpoosh S, Fotouhi F, Shokouhi Targhi H, Mazaheri V, Farahmand B. Association of IFITM3 rs12252 polymorphisms, BMI, diabetes, and hypercholesterolemia with mild flu in an Iranian population. Virol J. 2017;14:1–8.
Article
CAS
Google Scholar
Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet. 1997;24:1–8.
Article
CAS
PubMed
Google Scholar
Garred P, Pressler T, Madsen HO, Frederiksen B, Svejgaard A, Høiby N, Schwartz M, Koch C. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest. 1999;104:431–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ip WK, Chan KH, Law HK, Tso GH, Kong EK, Wong WH, To YF, Yung RW, Chow EY, Au KL, et al. Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection. J Infect Dis. 2005;191:1697–704.
Article
CAS
PubMed
Google Scholar
Tang YW, Cleavinger PJ, Li H, Mitchell PS, Smith TF, Persing DH. Analysis of candidate-host immunogenetic determinants in herpes simplex virus-associated Mollaret’s meningitis. Clin Infect Dis. 2000;30:176–8.
Article
CAS
PubMed
Google Scholar
McGuire W, Hill AV, Allsopp CE, Greenwood BM, Kwiatkowski D. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature. 1994;371:508–10.
Article
CAS
PubMed
Google Scholar
Mira JP, Cariou A, Grall F, Delclaux C, Losser MR, Heshmati F, Cheval C, Monchi M, Teboul JL, Riché F, et al. Association of tnf2, a tnf-α promoter polymorphism, with septic shock susceptibility and mortality: A multicenter study. J Am Med Assoc. 1999;282:561–8.
Article
CAS
Google Scholar
Zhang Y, Zhang Z, Cao L, Lin J, Yang Z, Zhang X. A common CD55 rs2564978 variant is associated with the susceptibility of non-small cell lung cancer. Oncotarget. 2017;8:6216–21.
Article
PubMed
Google Scholar
Shang Y, Chai N, Gu Y, Ding L, Yang Y, Zhou J, Ren G, Hao X, Fan D, Wu K, et al. Systematic immunohistochemical analysis of the Eexpression of CD46, CD55, and CD59 in colon cancer. Arch Pathol Lab Med. 2014;138:910–9.
Article
PubMed
Google Scholar
Bermejo-Martin JF, Martin-Loeches I, Rello J, Antón A, Almansa R, Xu L, Lopez-Campos G, Pumarola T, Ran L, Ramirez P, et al. Host adaptive immunity deficiency in severe pandemic influenza. Crit Care. 2010;14:R167–R167.
Article
PubMed
PubMed Central
Google Scholar
Chen JZ, Huang SD, Ji CN, Pang RY, Xie Y, Xue JL. Identification, expression pattern, and subcellular location of human RIP isoforms. DNA Cell Biol. 2005;24:464–9.
Article
CAS
PubMed
Google Scholar
Gabriel, S., Ziaugra, L., Tabbaa, D. SNP genotyping using the Sequenom MassARRAY iPLEX platform. Current Protocols in Human Genetics, 2009. 60: 2.12.1–2.12.18.
Tang YW, Li H, Wu H, Shyr Y, Edwards KM. Host single-nucleotide polymorphisms and altered responses to inactivated influenza vaccine. J Infect Dis. 2007;196:1021–5.
Article
CAS
PubMed
Google Scholar
Yang X, Tan B, Zhou X, Xue J, Zhang X, Wang P, Shao C, Li Y, Li C, Xia H, et al. Interferon-inducible transmembrane protein 3 genetic variant rs12252 and influenza susceptibility and severity: a meta-analysis. PLoS ONE. 2015;10:e0124985.
Article
PubMed
PubMed Central
CAS
Google Scholar
Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, et al. Evaluation of IFITM3 rs12252 association with severe pediatric influenza Iinfection. J Infect Dis. 2017;216:14–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wellington D, Laurenson-Schafer H, Abdel-Haq A, Dong T. IFITM3: How genetics influence influenza infection demographically. Biomedical Journal. 2019;42:19–26.
Article
PubMed
PubMed Central
Google Scholar
Kalliolias GD, Ivashkiv LB. TNF biology, pathogenic mechanisms and emerging therapeutic strategies. Nat Rev Rheumatol. 2016;12:49–62.
Article
CAS
PubMed
Google Scholar
McKinstry KK, Strutt TM, Buck A, Curtis JD, Dibble JP, Huston G, Tighe M, Hamada H, Sell S, Dutton RW, et al. IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. Journal of Immunology. 2009;182:7353–63.
Article
CAS
Google Scholar
Rojas JM, Avia M, Martín V, Sevilla N. IL-10: A multifunctional cytokine in viral infections. J Immunol Res. 2017;2017:6104054–6104054.
Article
PubMed
PubMed Central
CAS
Google Scholar
García-Ramírez RA, Ramírez-Venegas A, Quintana-Carrillo R, Camarena ÁE, Falfán-Valencia R, Mejía-Aranguré JM. TNF, IL6, and IL1B polymorphisms are associated with severe influenza A (H1N1) virus infection in the Mexican population. PLoS ONE. 2015;10:e0144832.
Article
PubMed
PubMed Central
CAS
Google Scholar
Rogo LD, Rezaei F, Marashi SM, Yekaninejad MS, Naseri M, Ghavami N, Mokhtari-Azad T. Seasonal influenza A/H3N2 virus infection and IL-1Β, IL-10, IL-17, and IL-28 polymorphisms in Iranian population. J Med Virol. 2016;88:2078–84.
Article
CAS
PubMed
Google Scholar
Keshavarz M, Namdari H, Farahmand M, Mehrbod P, Mokhtari-Azad T, Rezaei F. Association of polymorphisms in inflammatory cytokines encoding genes with severe cases of influenza A/H1N1 and B in an Iranian population. Virology Journal. 2019;16:1–10.
Article
CAS
Google Scholar
Zhao N, Chen H-L, Chen Z-Z, Li J, Chen Z-B. IL-10-592 polymorphism is associated with IL-10 expression and severity of enterovirus 71 infection in chinese children. J Clin Virol. 2017;95:42–6.
Article
CAS
PubMed
Google Scholar
Ferdinands JM, Denison AM, Dowling NF, Jost HA, Gwinn ML, Liu L, Zaki SR, Shay DK. A Pilot study of host genetic variants associated with influenza-associated deaths among children and young adults. Emerg Infect Dis. 2011;17:2294–302.
Article
CAS
PubMed
PubMed Central
Google Scholar
Choudhary ML, Alagarasu K, Chaudhary U, Kawale S, Malasane P, Gurav YK, Padbidri V, Kadam D, Sangle SA, Salvi S, et al. Association of single nucleotide polymorphisms in TNFA and IL10 genes with disease severity in influenza A/H1N1pdm09 virus infections: A study from Western India. Viral Immunol. 2018;31:683–8.
Article
CAS
PubMed
Google Scholar
Super M, Gillies SD, Foley S, Sastry K, Schweinle JE, Silverman VJ, Ezekowitz RAB. Distinct and overlapping functions of allelic forms of human mannose binding protein. Nat Genet. 1992;2:50–5.
Article
CAS
PubMed
Google Scholar
Gallagher PM, Lowe G, Fitzgerald T, Bella A, Greene CM, McElvaney NG, O’Neill SJ. Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. Thorax. 2003;58:154–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gomi K, Tokue Y, Kobayashi T, Takahashi H, Watanabe A, Fujita T, Nukiwa T. Mannose-binding lectin gene polymorphism is a modulating factor in repeated respiratory infections. Chest. 2004;26:95–9.
Article
Google Scholar
Dhand, N.K. and Khatkar, M.S. Statulator: An online statistical calculator. Sample Size Calculator for Estimating a Single Proportion. Accessed 14 August 2019 at http://statulator.com/SampleSize/ss1P.html; 2014.
Ornelas, A.M.d.M., Xavier-de-Carvalho, C., Alvarado-Arnez, L.E., Ribeiro-Alves, M., Rossi, Á.D., Tanuri, A., de Aguiar, R.S., Moraes, M.O., and Cardoso, C.C. Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil. Memorias do Instituto Oswaldo Cruz, 2019. 114: e190004.
Ravetch JV, Bolland S. IgG Fc receptors. Annu Rev Immunol. 2001;19:275–90.
Article
CAS
PubMed
Google Scholar
Boruchov AM, Heller G, Veri M-C, Bonvini E, Ravetch JV, Young JW. Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions. J Clin Investig. 2005;115:2914–23.
Article
CAS
PubMed
PubMed Central
Google Scholar
Duan J, Lou J, Zhang Q, Ke J, Qi Y, Shen N, Zhu B, Zhong R, Wang Z, Liu L, et al. A genetic variant rs1801274 in FCGR2A as a potential risk marker for Kawasaki disease: a case-control study and meta-analysis. PLoS ONE. 2014;9:e103329.
Article
PubMed
PubMed Central
Google Scholar
Bouglé A, Max A, Mongardon N, Grimaldi D, Pène F, Rousseau C, Chiche J-D, Bedos J-P, Vicaut E, Mira J-P. Protective effects of FCGR2A polymorphism in invasive pneumococcal diseases. Chest. 2012;142:1474–81.
Article
PubMed
Google Scholar
Chatzopoulou F, Gioula G, Kioumis I, Chatzidimitriou D, Exindari M. Identification of complement-related host genetic risk factors associated with influenza A(H1N1)pdm09 outcome: challenges ahead. Med Microbiol Immunol. 2019;208:631–40.
Article
CAS
PubMed
Google Scholar
Arcanjo AC, Mazzocco G, de Oliveira SF, Plewczynski D, Radomski JP. Role of the host genetic variability in the influenza A virus susceptibility. Acta Biochim Pol. 2014;61:403–19.
Article
PubMed
Google Scholar
Zheng YH, Yu HF, Peterlin BM. Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells. Nat Cell Biol. 2003;5:611–8.
Article
CAS
PubMed
Google Scholar
Lee N, Cao B, Ke C, Lu H, Hu Y, Tam CHT, Ma RCW, Guan D, Zhu Z, Li H, et al. IFITM3, TLR3, and CD55 gene SNPs and cumulative genetic risks for severe outcomes in Chinese patients with H7N9/H1N1pdm09 influenza. J Infect Dis. 2017;216:97–104.
Article
CAS
PubMed
Google Scholar
Park J, Seo T, Kim H, Choe J. Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies. Mol Cell Biol. 2005;25:8202–14.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ganna A. The Covid-Host Genetics Initiative; a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. Eur J Hum Genet. 2020;28:715–8.
Article
CAS
Google Scholar
Kachuri, L., Francis, S.S., Morrison, M., Boss, amp, amp, eacute, Y., Cavazos, T.B., Rashkin, S.R., Ziv, E., et al. The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2. MedRxiv, 2020. Preprint: 2020.05.01.20088054.