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Table 4 Frequency of 12 SNPs and their association with influenza A/H1N1 infection

From: Association of the host genetic factors, hypercholesterolemia and diabetes with mild influenza in an Iranian population

Gene and genotype Groups P Crude OR§ 95% CI
ILI
n (%)
Influenza A/H1N1
n (%)
rs1800450*      
CC 33 (84.6) 40 (88.9) 0.734 1
TT 1 (2.6) 0 (0)  
TC 5 (12.8) 5 (11.1)   0.8 0.2, 3.1
rs1800451*      
CC 38 (97.4) 45 (100) 0.464
CT 1 (2.6) 0 (0)  
rs1800629*      
GG 36 (85.7) 39 (84.8) 0.268 1
AA 2 (4.8) 0 (0)  
GA 4 (9.5) 7 (15.2)   1.6 0.4, 6.0
rs1800871      
GG 17 (43.6) 19 (44.2) 0.425 1 -
AA 2 (5.1) 6 (14.0)   2.7 0.5, 15.1
GA 20 (51.3) 18 (41.8)   0.8 0.3, 2.0
rs1800872      
GG 18 (45.0) 18 (47.4) 0.616 1
TT 2 (5.0) 4 (10.5)   2.0 0.3, 12.3
GT 20 (50.0) 16 (42.1)   0.8 0.3, 2.0
rs1800896      
CC 2 (5.3) 4 (9.8) 0.832 1
TT 20 (52.6) 20 (48.8)   0.5 0.1, 3.1
CT 16 (42.1) 17 (41.5)   0.5 0.1, 3.3
rs1801274      
GG 5 (12.2) 9 (22.0) 0.056 1
AA 12 (29.3) 19 (46.3)   0.9 0.2, 3.3
GA 24 (58.5) 13 (31.7)   0.3 0.1, 1.1
rs2564978      
CC 25 (65.8) 29 (69.1) 0.938 1
TT 3 (7.9) 4 (9.5)   1.2 0.2, 5.6
CT 10 (26.3) 9 (21.4)   0.8 0.3, 2.2
rs361525      
GG 8 (20.5) 10 (23.8) 0.681 1
AA 14 (35.9) 11 (26.2)   0.6 0.2, 2.1
GA 17 (43.6) 21 (50.0)   1.0 0.3, 3.1
rs3786054      
AA 7 (23.3) 2 (5.9) 0.027 1
GG 11 (36.7) 23 (67.7)   7.3 1.3, 41.1
AG 12 (40.0) 9 (26.5)   2.6 0.4, 15.8
rs8070740      
AA 13 (31.7) 28 (65.1) 0.007 1
GG 10 (24.4) 4 (9.3)   5.4 1.4, 20.4
GA 18 (43.9) 11 (25.6)   1.5 0.4, 6.1
rs9856661      
CC 5 (12.5) 4 (9.8) 0.272 1
AA 19 (47.5) 27 (65.8)   1.8 0.4, 7.5
CA 16 (40.0) 10 (24.4)   0.8 0.2, 3.6
  1. *Odds ratio has not been estimated for the genotypes with zero observations
  2. §Significant odds ratios (ie., P < 0.05) are bolded (Prs 3786054: 0.0140; Prs 8070740: 0.0093). ILI: influenza like illness; OR: odds ratio