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Table 4 Frequency of 12 SNPs and their association with influenza A/H1N1 infection

From: Association of the host genetic factors, hypercholesterolemia and diabetes with mild influenza in an Iranian population

Gene and genotype

Groups

P

Crude OR§

95% CI

ILI

n (%)

Influenza A/H1N1

n (%)

rs1800450*

     

CC

33 (84.6)

40 (88.9)

0.734

1

−

TT

1 (2.6)

0 (0)

 

−

−

TC

5 (12.8)

5 (11.1)

 

0.8

0.2, 3.1

rs1800451*

     

CC

38 (97.4)

45 (100)

0.464

−

−

CT

1 (2.6)

0 (0)

 

−

−

rs1800629*

     

GG

36 (85.7)

39 (84.8)

0.268

1

−

AA

2 (4.8)

0 (0)

 

−

−

GA

4 (9.5)

7 (15.2)

 

1.6

0.4, 6.0

rs1800871

     

GG

17 (43.6)

19 (44.2)

0.425

1

-

AA

2 (5.1)

6 (14.0)

 

2.7

0.5, 15.1

GA

20 (51.3)

18 (41.8)

 

0.8

0.3, 2.0

rs1800872

     

GG

18 (45.0)

18 (47.4)

0.616

1

−

TT

2 (5.0)

4 (10.5)

 

2.0

0.3, 12.3

GT

20 (50.0)

16 (42.1)

 

0.8

0.3, 2.0

rs1800896

     

CC

2 (5.3)

4 (9.8)

0.832

1

−

TT

20 (52.6)

20 (48.8)

 

0.5

0.1, 3.1

CT

16 (42.1)

17 (41.5)

 

0.5

0.1, 3.3

rs1801274

     

GG

5 (12.2)

9 (22.0)

0.056

1

−

AA

12 (29.3)

19 (46.3)

 

0.9

0.2, 3.3

GA

24 (58.5)

13 (31.7)

 

0.3

0.1, 1.1

rs2564978

     

CC

25 (65.8)

29 (69.1)

0.938

1

−

TT

3 (7.9)

4 (9.5)

 

1.2

0.2, 5.6

CT

10 (26.3)

9 (21.4)

 

0.8

0.3, 2.2

rs361525

     

GG

8 (20.5)

10 (23.8)

0.681

1

−

AA

14 (35.9)

11 (26.2)

 

0.6

0.2, 2.1

GA

17 (43.6)

21 (50.0)

 

1.0

0.3, 3.1

rs3786054

     

AA

7 (23.3)

2 (5.9)

0.027

1

−

GG

11 (36.7)

23 (67.7)

 

7.3

1.3, 41.1

AG

12 (40.0)

9 (26.5)

 

2.6

0.4, 15.8

rs8070740

     

AA

13 (31.7)

28 (65.1)

0.007

1

−

GG

10 (24.4)

4 (9.3)

 

5.4

1.4, 20.4

GA

18 (43.9)

11 (25.6)

 

1.5

0.4, 6.1

rs9856661

     

CC

5 (12.5)

4 (9.8)

0.272

1

−

AA

19 (47.5)

27 (65.8)

 

1.8

0.4, 7.5

CA

16 (40.0)

10 (24.4)

 

0.8

0.2, 3.6

  1. *Odds ratio has not been estimated for the genotypes with zero observations
  2. §Significant odds ratios (ie., P < 0.05) are bolded (Prs 3786054: 0.0140; Prs 8070740: 0.0093). ILI: influenza like illness; OR: odds ratio