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  1. Self-inactivating retroviral vectors (SIN) are often associated with very low titers. Promoter elements embedded within SIN designs may suppress transcription of packageable retroviral RNA which in turn result...

    Authors: Diana E Jaalouk, Milena Crosato, Pnina Brodt and Jacques Galipeau
    Citation: Virology Journal 2006 3:27
  2. Primary HIV infection can develop from exposure to HIV in the oral cavity. In previous studies, we have documented rapid and extensive binding of HIV virions in seminal plasma to intact mucosal surfaces of the...

    Authors: Renu B Kumar, Diane M Maher, Mark C Herzberg and Peter J Southern
    Citation: Virology Journal 2006 3:25
  3. The study aimed at developing a real-time quantitative PCR assay to monitor HBV serum virus load of chronic carriers enrolled in therapeutic trials.

    Authors: Maimuna E Mendy, Steve Kaye, Marianne van der Sande, Pura Rayco-Solon, Pauline A Waight, Deborah Shipton, Dorka Awi, Paul Snell, Hilton Whittle and Samuel J McConkey
    Citation: Virology Journal 2006 3:23
  4. Infection of macaques with the avirulent molecular clone SIVmac1A11 results in transient low viremia and no disease. To investigate if this low viremia is solely due to intrinsic poor replication fitness or is...

    Authors: Koen KA Van Rompay, Emily J Blackwood, Gary Landucci, Don Forthal and Marta L Marthas
    Citation: Virology Journal 2006 3:22
  5. Human Cytomegalovirus (HCMV) continues to be an important cause of morbidity and occasional mortality in immunocompromised patients. Polymerase chain reaction (PCR) is the most sensitive and commonly used meth...

    Authors: P Sowmya, HN Madhavan and KL Therese
    Citation: Virology Journal 2006 3:20
  6. Here we briefly report testosterone and cytokine responses to Venezuelan equine encephalitis virus (VEEV) in macaques which were used as part of a larger study conducted by the Department of Defense to better ...

    Authors: Michael P Muehlenbein, Frank B Cogswell, Mark A James, James Koterski and George V Ludwig
    Citation: Virology Journal 2006 3:19
  7. Inhibition of the human cytomegalovirus UL97 kinase by maribavir is thought to be responsible for the antiviral activity of this compound. Some mutations that confer resistance to maribavir map to UL97, however a...

    Authors: Mark N Prichard, Debra C Quenelle, Deborah J Bidanset, Gloria Komazin, Sunwen Chou, John C Drach and Earl R Kern
    Citation: Virology Journal 2006 3:18
  8. The distribution of deformed wing virus infection within the honey bee reproductive castes (queens, drones) was investigated by in situ hybridization and immunohistology from paraffin embedded sections. Digoxygen...

    Authors: Julie Fievet, Diana Tentcheva, Laurent Gauthier, Joachim de Miranda, François Cousserans, Marc Edouard Colin and Max Bergoin
    Citation: Virology Journal 2006 3:16
  9. The Coccolithoviridae is a recently discovered family of viruses that infect the marine coccolithophorid Emiliania huxleyi. Following on from the sequencing of the type strain EhV-86, we have sequenced a second s...

    Authors: Michael J Allen, Declan C Schroeder, Andrew Donkin, Katharine J Crawfurd and William H Wilson
    Citation: Virology Journal 2006 3:15
  10. A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 ba...

    Authors: Dhanalakshmi Chinnasamy, Michael D Milsom, James Shaffer, James Neuenfeldt, Aimen F Shaaban, Geoffrey P Margison, Leslie J Fairbairn and Nachimuthu Chinnasamy
    Citation: Virology Journal 2006 3:14
  11. Papillomaviruses undergo a complex life cycle requiring regulated DNA replication. The papillomavirus E1 helicase is essential for viral DNA replication and plays a key role in controlling viral genome copy nu...

    Authors: Michael R Lentz, Stanley M Stevens Jr, Joshua Raynes and Nancy Elkhoury
    Citation: Virology Journal 2006 3:13
  12. Panicum mosaic virus (PMV) has a positive-sense, single-stranded RNA genome that serves as the mRNA for two 5'-proximal genes, p48 and p112. The p112 open reading frame (ORF) has a GDD-motif, a feature of virus R...

    Authors: Jeffrey S Batten, Massimo Turina and Karen-Beth G Scholthof
    Citation: Virology Journal 2006 3:12
  13. D-type simian retrovirus-2 (SRV-2) causes an AIDS-like immune deficiency syndrome (SAIDS) in various macaque species. SAIDS is often accompanied by retroperitoneal fibromatosis (RF), an aggressive fibroprolife...

    Authors: Jeannette Philipp-Staheli, Taya Marquardt, Margaret E Thouless, A Gregory Bruce, Richard F Grant, Che-Chung Tsai and Timothy M Rose
    Citation: Virology Journal 2006 3:11
  14. Although many vaccinia virus proteins have been identified and studied in detail, only a few studies have attempted a comprehensive survey of the protein composition of the vaccinia virion. These projects have...

    Authors: Jennifer D Yoder, Tsefang S Chen, Cliff R Gagnier, Srilakshmi Vemulapalli, Claudia S Maier and Dennis E Hruby
    Citation: Virology Journal 2006 3:10
  15. Genetic redirection of lymphocytes that have been genetically engineered to recognize antigens other than those originally programmed in their germlines is a potentially powerful tool for immunotherapy of canc...

    Authors: Anthony Simmons, Robert P Whitehead, Andrey A Kolokoltsov and Robert A Davey
    Citation: Virology Journal 2006 3:8
  16. A 21-year-old man presented with nasal obstruction of the right nasal fossa of 1 year duration. Nasal endoscopy revealed in the right inferior turbinate head a rounded neoplasm about 1 cm in diameter.

    Authors: Matteo Gelardi, Marilena Tomaiuolo, Michele Cassano, Gaspare Besozzi, Maria Luisa Fiorella, Agata Calvario, Maria Antonia Castellano and Pasquale Cassano
    Citation: Virology Journal 2006 3:6
  17. Nicotiana benthamiana plants were stably transformed with an intron-spliced dsRNA producing construct cognate to bidirectional promoter of African cassava mosaic geminivirus (ACMV) DNA A. Transgenic lines express...

    Authors: Afzal Muhammad Dogar
    Citation: Virology Journal 2006 3:5
  18. Although the sequence of the human cytomegalovirus (HCMV) genome is generally conserved among unrelated clinical strains, some open reading frames (ORFs) are highly variable. UL146 and UL147, which encode CXC ...

    Authors: Nell S Lurain, Andrea M Fox, Heather M Lichy, Sangeeta M Bhorade, Carl F Ware, Diana D Huang, Sau-Ping Kwan, Edward R Garrity and Sunwen Chou
    Citation: Virology Journal 2006 3:4
  19. Human polyomavirus JC (JCV), the etiological agent of the disease progressive multifocal leukoencephalopathy (PML) affects immunocompromised patients particularly patients with AIDS. In vitro studies of JCV infec...

    Authors: Moti L Chapagain, Taylor Nguyen, Thomas Bui, Saguna Verma and Vivek R Nerurkar
    Citation: Virology Journal 2006 3:3
  20. Encephalitis caused by flaviviruses, Japanese encephalitis virus (JEV) and West Nile virus (WNV) is responsible for significant morbidity and mortality in many endemic countries. Dengue-2 (Den-2) virus is a re...

    Authors: Rangaiah S Jayakeerthi, Raghava V Potula, S Srinivasan and S Badrinath
    Citation: Virology Journal 2006 3:2
  21. The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses. In this report, we sought to determine whe...

    Authors: Ziying Han and Ronald N Harty
    Citation: Virology Journal 2005 2:92
  22. Molecular epidemiological investigation of measles outbreaks can document the interruption of endemic measles transmission and is useful for establishing and clarifying epidemiological links between cases in g...

    Authors: Michaela A Riddell, Jennifer S Rota and Paul A Rota
    Citation: Virology Journal 2005 2:87
  23. Poliovirus protein 3CDpro possesses both proteinase and RNA binding activities, which are located in the 3Cpro domain of the protein. The RNA polymerase (3Dpol) domain of 3CDpro modulates these activities of the ...

    Authors: David Franco, Harsh B Pathak, Craig E Cameron, Bart Rombaut, Eckard Wimmer and Aniko V Paul
    Citation: Virology Journal 2005 2:86
  24. Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants and young children. Although several experimental RSV vaccines are under investigation, immuno therapy is th...

    Authors: Edyta Zielinska, Daiqing Liu, Hong-Yin Wu, Jorge Quiroz, Ruth Rappaport and Da-Ping Yang
    Citation: Virology Journal 2005 2:84
  25. Inactive carriers forms the largest group in chronic HBV infected patients. Around 300 million people are inactive carriers The inactive HBsAg carrier state is diagnosed by absence of HBeAg and presence of ant...

    Authors: Sanjeev Kumar Sharma, Nitin Saini and Yogesh Chwla
    Citation: Virology Journal 2005 2:82
  26. Hepatitis C virus (HCV) infection is of growing concern in public health with around 350 million chronically infected individuals worldwide. Although the IFN-α/rivabirin is the only approved therapy with 10–30...

    Authors: Carmen E Gómez, Andrée Marie Vandermeeren, María Angel García, Elena Domingo-Gil and Mariano Esteban
    Citation: Virology Journal 2005 2:81
  27. In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8) [1]. This novel herpesvirus has and continues to present challenges to define its scope of i...

    Authors: Daniel C Edelman
    Citation: Virology Journal 2005 2:78
  28. Acute retinal necrosis is a sight-threatening disease caused by the group of herpesviruses. The aim of this paper is to report a case of acute retinal necrosis following ocular trauma in a patient initially tr...

    Authors: Petra Svozílková, Eva Říhová, Pavel Diblík, Pavel Kuthan, Zdeněk Kovařík and Bohdana Kalvodová
    Citation: Virology Journal 2005 2:77
  29. Infectious salmon anaemia (ISA) is a highly fatal viral disease affecting marine-farmed Atlantic salmon which is caused by ISA virus (ISAV), a fish orthomyxovirus that has recently been assigned to the new genus

    Authors: Molly JT Kibenge, Khalid Munir and Frederick SB Kibenge
    Citation: Virology Journal 2005 2:75
  30. The entry of the SARS coronavirus (SCV) into cells is initiated by binding of its spike envelope glycoprotein (S) to a receptor, ACE2. We and others identified the receptor-binding domain (RBD) by using S frag...

    Authors: Samitabh Chakraborti, Ponraj Prabakaran, Xiaodong Xiao and Dimiter S Dimitrov
    Citation: Virology Journal 2005 2:73
  31. Previous studies presented the quasispecies spectrum of the envelope region of dengue virus type 3 (DENV-3) from either clinical specimens or field-caught mosquitoes. However, the extent of sequence variation ...

    Authors: Day-Yu Chao, Chwan-Chuen King, Wei-Kung Wang, Wei-June Chen, Hui-Lin Wu and Gwong-Jen J Chang
    Citation: Virology Journal 2005 2:72
  32. White spot syndrome virus (WSSV) is an important pathogen of the penaeid shrimp with high mortalities. In previous reports, Orf427 of WSSV is characterized as one of the three major latency-associated genes of WS...

    Authors: Liqun Lu, Hai Wang, Ivanus Manopo, Li Yu and Jimmy Kwang
    Citation: Virology Journal 2005 2:71
  33. Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol

    Authors: Richard Sallie
    Citation: Virology Journal 2005 2:70
  34. Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

    Authors: Martin J Vincent, Eric Bergeron, Suzanne Benjannet, Bobbie R Erickson, Pierre E Rollin, Thomas G Ksiazek, Nabil G Seidah and Stuart T Nichol
    Citation: Virology Journal 2005 2:69