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  1. Motavizumab (MEDI-524) is a monoclonal antibody with enhanced neutralizing activity against RSV. In mice, motavizumab suppressed RSV replication which resulted in significant reduction of clinical parameters o...

    Authors: Asunción Mejías, Susana Chávez-Bueno, Martin B Raynor, John Connolly, Peter A Kiener, Hasan S Jafri and Octavio Ramilo
    Citation: Virology Journal 2007 4:109
    Content type: Short report Published on:

  2. The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MA...

    Authors: Kelly L Warfield, Derron A Alves, Steven B Bradfute, Daniel K Reed, Sean VanTongeren, Warren V Kalina, Gene G Olinger and Sina Bavari
    Citation: Virology Journal 2007 4:108
    Content type: Research Published on:

  3. We have developed a system that isolates and replicates HCV in vitro. These isolates are called CIMM-HCV. This system has made it possible to analyze the biology, nature, and extent of HCV variability, among othe...

    Authors: S Zaki Salahuddin, Katherine A Snyder, Andre Godwin, Renu Grewal, John G Prichard, Ann S Kelley and Dennis Revie
    Citation: Virology Journal 2007 4:106
    Content type: Research Published on:

  4. The nucleoprotein (NP) of Marburg virus (MARV) is responsible for the encapsidation of viral genomic RNA and the formation of the helical nucleocapsid precursors that accumulate in intracellular inclusions in ...

    Authors: Andrea DiCarlo, Peggy Möller, Angelika Lander, Larissa Kolesnikova and Stephan Becker
    Citation: Virology Journal 2007 4:105
    Content type: Research Published on:

  5. The epidemiology of viral hepatitis during pregnancy is essential for health planners and programme managers. While much data exist concerning viral hepatitis during pregnancy in many African countries, no pro...

    Authors: Rasha M Elsheikh, Ahmed A Daak, Mohamed A Elsheikh, Mubarak S Karsany and Ishag Adam
    Citation: Virology Journal 2007 4:104
    Content type: Research Published on:

  6. Human adenovirus serotype 5 (Ad5) has been widely explored as a gene delivery vector for a variety of diseases. Many target cells, however, express low levels of Ad5 native receptor, the Coxsackie-Adenovirus R...

    Authors: Tie Han, Yizhe Tang, Hideyo Ugai, Leslie E Perry, Gene P Siegal, Juan L Contreras and Hongju Wu
    Citation: Virology Journal 2007 4:103
    Content type: Research Published on:

  8. Viruses that are incorporating host cell proteins might trigger autoimmune diseases. It is therefore of interest to identify possible host proteins associated with viruses, especially for enveloped viruses tha...

    Authors: Maria Hammarstedt, Jenny Ahlqvist, Steven Jacobson, Henrik Garoff and Anna Fogdell-Hahn
    Citation: Virology Journal 2007 4:101
    Content type: Research Published on:

  9. The human immunodeficiency virus type 1 (HIV-1) has been intensely investigated since its discovery in 1983 as the cause of acquired immune deficiency syndrome (AIDS). With relatively few proteins made by the ...

    Authors: Joshua M Costin
    Citation: Virology Journal 2007 4:100
    Content type: Review Published on:

  10. The adeno-associated virus (AAV) has rapidly gained popularity in gene therapy since the establishment of the first AAV2 infectious clone, in 1982, due to some of their distinguishing characteristics such as l...

    Authors: Renata dosSantos Coura and Nance Beyer Nardi
    Citation: Virology Journal 2007 4:99
    Content type: Review Published on:

    The Erratum to this article has been published in Virology Journal 2010 7:12

  11. Genotype 4 hepatitis E virus (HEV) was reportedly transmitted freely between humans and swine in eastern China. The full-length genomic sequence of Shanghai swine isolate (SH-SW-zs1) recovered from feces sampl...

    Authors: Quan Shen, Wen Zhang, Xiangrong Cao, Jing Mou, Li Cui and Xiuguo Hua
    Citation: Virology Journal 2007 4:98
    Content type: Research Published on:

  12. The recently sequenced 218 kb genome of morphologically atypical Bacillus thuringiensis phage 0305φ8-36 exhibited only limited detectable homology to known bacteriophages. The only known relative of this phage is...

    Authors: Stephen C Hardies, Julie A Thomas and Philip Serwer
    Citation: Virology Journal 2007 4:97
    Content type: Research Published on:

  13. Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is the predominant species of domestic rabbit throughout t...

    Authors: Michael T McIntosh, Shawn C Behan, Fawzi M Mohamed, Zhiqiang Lu, Karen E Moran, Thomas G Burrage, John G Neilan, Gordon B Ward, Giuliana Botti, Lorenzo Capucci and Samia A Metwally
    Citation: Virology Journal 2007 4:96
    Content type: Research Published on:

  14. Natural multiple viral infections of cultivated cowpeas have been reported in Nigeria. In this study, three Nigerian commercial cowpea cultivars ("Olo 11", "Oloyin" and "White") and two lines from the IITA (IT...

    Authors: Moni A Taiwo, Kehinde T Kareem, Imade Y Nsa and Jackies D'A Hughes
    Citation: Virology Journal 2007 4:95
    Content type: Research Published on:

  15. Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species. However, there is very little information ...

    Authors: Béatrice Pignolet, Jean-Luc Duteyrat, Aude Allemandou, Jacqueline Gelfi, Gilles Foucras and Stéphane Bertagnoli
    Citation: Virology Journal 2007 4:94
    Content type: Short report Published on:

  16. Hepatitis B virus (HBV) infection is a serious health problem worldwide. Treatment recommendation and response are mainly indicated by viral load, e antigen (HBeAg) seroconversion, and ALT levels. The S antige...

    Authors: Min Lian, Xu Zhou, Lai Wei, Shihong Qiu, Tong Zhou, Lanfen Li, Xiaocheng Gu, Ming Luo and Xiaofeng Zheng
    Citation: Virology Journal 2007 4:93
    Content type: Methodology Published on:

  17. The highly heterogenic characteristic of viruses is the major obstacle to efficient DNA amplification. Taking advantage of the large number of virus DNA sequences in public databases to select conserved sites ...

    Authors: Qingrun Zhang, Guanghua Wu, Elliott Richards, Shan'gang Jia and Changqing Zeng
    Citation: Virology Journal 2007 4:92
    Content type: Methodology Published on:

    The Retraction Note to this article has been published in Virology Journal 2007 4:119

  18. Dengue and Dengue hemorrhagic fever have emerged as some of the most important mosquito-borne viral diseases in the tropics. The mechanisms of pathogenesis of Dengue remain elusive. Recently, virus-induced apo...

    Authors: Indira Umareddy, Olivier Pluquet, Qing Yin Wang, Subhash G Vasudevan, Eric Chevet and Feng Gu
    Citation: Virology Journal 2007 4:91
    Content type: Research Published on:

  19. The genetic characterization of wild-type measles strains isolated during an epidemic cluster of measles occurred in Puglia (South Italy), between November 2006 and January 2007, was performed. Measles virus (...

    Authors: Maria Chironna, Rosa Prato, Anna Sallustio, Domenico Martinelli, Cinzia Germinario, Pierluigi Lopalco and Michele Quarto
    Citation: Virology Journal 2007 4:90
    Content type: Short report Published on:

  20. Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The ...

    Authors: Sidhartha Hazari, Lizeth Taylor, Salima Haque, Robert F Garry, Sander Florman, Ronald Luftig, Frederic Regenstein and Srikanta Dash
    Citation: Virology Journal 2007 4:89
    Content type: Research Published on:

  21. Endothelial cells are a target for gene therapy because they are implicated in a number of vascular diseases. Recombinant baculovirus have emerged as novel gene delivery vectors. However, there is no informati...

    Authors: Agustín Luz-Madrigal, Carmen Clapp, Jorge Aranda and Luis Vaca
    Citation: Virology Journal 2007 4:88
    Content type: Research Published on:

  22. Kaposi's sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a highly vascularized neoplasm characterized by endothelial-derived spindle-shaped tumor cells. KSHV-infected mic...

    Authors: Bryan D Shelby, Heather L LaMarca, Harris E McFerrin, Anne B Nelson, Joseph A Lasky, Gang Sun, Leslie Myatt, Margaret K Offermann, Cindy A Morris and Deborah E Sullivan
    Citation: Virology Journal 2007 4:87
    Content type: Research Published on:

  23. Noroviruses are the most common cause of non-bacterial gastroenteritis. Improved detection methods have seen a large increase in the number of human NoV genotypes in the last ten years. The objective of this s...

    Authors: John F Menton, Karen Kearney and John G Morgan
    Citation: Virology Journal 2007 4:86
    Content type: Research Published on:

  24. HTLV-I infected CD4+ T-cells lines usually progress towards a CD3- or CD3low phenotype. In this paper, we studied expression, kinetics, chromatin remodeling of the CD3 gene at different time-points post HTLV-I in...

    Authors: Haidar Akl, Bassam Badran, Gratiela Dobirta, Germain Manfouo-Foutsop, Maria Moschitta, Makram Merimi, Arsène Burny, Philippe Martiat and Karen E Willard-Gallo
    Citation: Virology Journal 2007 4:85
    Content type: Research Published on:

  25. Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often ...

    Authors: Sandra Prepens, Karl-Anton Kreuzer, Fabian Leendertz, Andreas Nitsche and Bernhard Ehlers
    Citation: Virology Journal 2007 4:84
    Content type: Methodology Published on:

  26. Japanese encephalitis virus (JEV) is a member of mosquito-borne Flaviviridae. To date, the mechanisms of the early events of JEV infection remain poorly understood, and the cellular receptors are unidentified. Th...

    Authors: Junping Ren, Tianbing Ding, Wei Zhang, Jianhua Song and Wenyu Ma
    Citation: Virology Journal 2007 4:83
    Content type: Hypothesis Published on:

  27. Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression ...

    Authors: Rasha Hammamieh, Mohsen Barmada, George Ludwig, Sheila Peel, Nick Koterski and Marti Jett
    Citation: Virology Journal 2007 4:82
    Content type: Research Published on:

  28. The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein ess...

    Authors: Amjad Hussain, Suman R Das, Charu Tanwar and Shahid Jameel
    Citation: Virology Journal 2007 4:81
    Content type: Research Published on:

  29. Thottapalayam (TPM) virus belongs to the genus Hantavirus, family Bunyaviridae. The genomes of hantaviruses consist of three negative-stranded RNA segments (S, M and L) encoding the virus nucleocapsid (N), glycop...

    Authors: Pragya D Yadav, Martin J Vincent and Stuart T Nichol
    Citation: Virology Journal 2007 4:80
    Content type: Short report Published on:

  30. Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. Previous and recent studies have suggested a diversification of type ...

    Authors: Gonzalo Moratorio, Mariela Martínez, María F Gutiérrez, Katiuska González, Rodney Colina, Fernando López-Tort, Lilia López, Ricardo Recarey, Alejandro G Schijman, María P Moreno, Laura García-Aguirre, Aura R Manascero and Juan Cristina
    Citation: Virology Journal 2007 4:79
    Content type: Research Published on:

  32. In 2005 huge epizooty of H5N1 HPAI occurred in Russia. It had been clear that territory of Russia becoming endemic for H5N1 HPAI. In 2006 several outbreaks have occurred. To develop new vaccines and antiviral ...

    Authors: Vasily A Evseenko, Eugeny K Bukin, Anna V Zaykovskaya, Kirill A Sharshov, Vladimir A Ternovoi, George M Ignatyev and Alexander M Shestopalov
    Citation: Virology Journal 2007 4:77
    Content type: Research Published on:

  33. Profilins are critical to cytoskeletal dynamics in eukaryotes; however, little is known about their viral counterparts. In this study, a poxviral profilin homolog, ectromelia virus strain Moscow gene 141 (ECTV...

    Authors: Christine Butler-Cole, Mary J Wagner, Melissa Da Silva, Gordon D Brown, Robert D Burke and Chris Upton
    Citation: Virology Journal 2007 4:76
    Content type: Research Published on:

  34. The Sydney blood bank cohort (SBBC) of long-term survivors consists of multiple individuals infected with attenuated, nef-deleted variants of human immunodeficiency virus type 1 (HIV-1) acquired from a single sou...

    Authors: Lachlan Gray, Melissa J Churchill, Jasminka Sterjovski, Kristie Witlox, Jennifer C Learmont, John S Sullivan, Steven L Wesselingh, Dana Gabuzda, Anthony L Cunningham, Dale A McPhee and Paul R Gorry
    Citation: Virology Journal 2007 4:75
    Content type: Research Published on:

  35. There are eight genotypes of hepatitis B virus (A-H) and subgenotypes are recognized. Genotyping can be accomplished based on a partial sequence of HBV genome such as the pre-S or S gene. Several methods have ...

    Authors: Abdel-Rahman N Zekri, Mohamed M Hafez, Nahed I Mohamed, Zeinab K Hassan, Manal H El-Sayed, Mohsen M Khaled and Tarek Mansour
    Citation: Virology Journal 2007 4:74
    Content type: Research Published on:

  38. To elucidate the relationship between resistance to HRSV neutralizing antibodies directed against the F protein and the fusion activity of the F protein, a recombinant approach was used to generate a panel of ...

    Authors: Changbao Liu, Nicole D Day, Patrick J Branigan, Lester L Gutshall, Robert T Sarisky and Alfred M Del Vecchio
    Citation: Virology Journal 2007 4:71
    Content type: Short report Published on:

  41. The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endo...

    Authors: Rosa E Sarmiento, Rocio G Tirado, Laura E Valverde and Beatriz Gómez-Garcia
    Citation: Virology Journal 2007 4:68
    Content type: Research Published on:

  42. Two recombinant, live attenuated human parainfluenza virus type 1 (rHPIV1) mutant viruses have been developed, using a reverse genetics system, for evaluation as potential intranasal vaccine candidates. These ...

    Authors: Emmalene J Bartlett, Adam Castaño, Sonja R Surman, Peter L Collins, Mario H Skiadopoulos and Brian R Murphy
    Citation: Virology Journal 2007 4:67
    Content type: Research Published on:

  43. HTLV-1 Gag protein is a matrix protein that contains the PTAP and PPPY sequences as L-domain motifs and which can be released from mammalian cells in the form of virus-like particles (VLPs). The cellular facto...

    Authors: Shuzo Urata, Hideyoshi Yokosawa and Jiro Yasuda
    Citation: Virology Journal 2007 4:66
    Content type: Research Published on:

  44. PCR-based detection and identification of viruses assumes a known, relatively stable genome. Unfortunately, high mutation rates may lead to extensive changes in viral nucleic acid sequences making dedicated PC...

    Authors: Amy L Clem, Jonathan Sims, Sucheta Telang, John W Eaton and Jason Chesney
    Citation: Virology Journal 2007 4:65
    Content type: Research Published on:

  45. Lysogenic mode of life cycle of a temperate bacteriophage is generally maintained by a protein called 'repressor'. Repressor proteins of temperate lambdoid phages bind to a few symmetric operator DNAs in order...

    Authors: Tridib Ganguly, Amitava Bandhu, Partho Chattoraj, Palas K Chanda, Malabika Das, Nitai C Mandal and Subrata Sau
    Citation: Virology Journal 2007 4:64
    Content type: Research Published on:

  46. The epidemiological significance of Hepatitis B virus genotypes has been well established and becoming an essential concern day by day however, much little is known about the mixed infection with more than one...

    Authors: Muhammad Masroor Alam, Sohail Zahoor Zaidi, Shehzad Shaukat, Salmaan Sharif, Mehar Angez, Asif Naeem, Shamim Saleha, Javed Aslam Butt and Salman Akbar Malik
    Citation: Virology Journal 2007 4:63
    Content type: Research Published on:

  50. The purposes of the study were to assess the usefulness of simultaneously amplifying herpes simplex virus 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and human herpesvirus 6 DNA in var...

    Authors: Georgia Vrioni, Christos Kalogeropoulos, Constantina Gartzonika, Efthalia Priavali and Stamatina Levidiotou
    Citation: Virology Journal 2007 4:59
    Content type: Short report Published on:
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  • ISSN: 1743-422X (electronic)

Virology Journal

ISSN: 1743-422X