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  1. Poxvirus-vectored vaccines against infectious diseases and cancer are currently under development. We hypothesized that the extensive use of poxvirus-vectored vaccine in future might result in co-infection and...

    Authors: Malachy Ifeanyi Okeke, Øivind Nilssen, Ugo Moens, Morten Tryland and Terje Traavik
    Citation: Virology Journal 2009 6:55
    Content type: Research Published on:

  2. An unprecedented high proportion of oseltamivir resistant influenza A(H1N1) viruses emerged in the 2007–08 influenza season. In Norway, two thirds of all tested A(H1N1) viruses were resistant to the antiviral ...

    Authors: Siri H Hauge, Hege S Blix, Katrine Borgen, Olav Hungnes, Susanne G Dudman and Preben Aavitsland
    Citation: Virology Journal 2009 6:54
    Content type: Short report Published on:

  3. The frequent oral shedding of herpes simplex virus type 1 (HSV-1) in the absence of clinical disease suggests that symptomatic HSV-1 recurrences may be inhibited by the mucosal environment. Indeed, saliva has ...

    Authors: Hannamari Välimaa, Jorma Tenovuo, Matti Waris and Veijo Hukkanen
    Citation: Virology Journal 2009 6:53
    Content type: Short report Published on:

  4. Phylogenetic analysis of three genes of Penguinpox virus, a novel Avipoxvirus isolated from African penguins, reveals its relationship to other poxviruses. The genes corresponding to Vaccinia virus G8R (VLTF-1...

    Authors: Olivia Carulei, Nicola Douglass and Anna-Lise Williamson
    Citation: Virology Journal 2009 6:52
    Content type: Short report Published on:

  6. The triple-gene-block protein 2 (TGBp2) of Bamboo mosaic virus (BaMV) is a transmembrane protein which was proposed to be involved in viral RNA binding during virus transport. Here, we report on the RNA-binding p...

    Authors: Hsiu-Ting Hsu, Yang-Hao Tseng, Yuan-Lin Chou, Shiaw-Hwa Su, Yau-Heiu Hsu and Ban-Yang Chang
    Citation: Virology Journal 2009 6:50
    Content type: Short report Published on:

  7. In this study, the upregulated expression level of vascular endothelial growth factor (VEGF) in a pulmonary endothelial cell line (HPMEC-ST1.6R) infected with dengue virus serotypes 1, 2, 3, and 4 (DENV-1, -2,...

    Authors: Azliyati Azizan, Kelly Fitzpatrick, Aimee Signarovitz, Richard Tanner, Heidi Hernandez, Lillian Stark and Mark Sweat
    Citation: Virology Journal 2009 6:49
    Content type: Short report Published on:

  8. As part of a routine screening for the possible presence of the necrotic strains of potato virus Y affecting potatoes in Mexico, five PVY isolates were submitted to biological and molecular analysis. Consideri...

    Authors: Victoriano Roberto Ramírez-Rodríguez, Katia Aviña-Padilla, Gustavo Frías-Treviño, Laura Silva-Rosales and Juan Pablo Martínez-Soriano
    Citation: Virology Journal 2009 6:48
    Content type: Research Published on:

  9. Orf virus (ORFV), the prototype of the genus Parapoxvirus (PPV), is the etiological agent of contagious ecthyma, a severe exanthematic dermatitis that afflicts domestic and wild small ruminants. Although South Am...

    Authors: Jônatas S Abrahão, Rafael K Campos, Giliane S Trindade, Maria IM Guedes, Zélia IP Lobato, Carlos Mazur, Paulo CP Ferreira, Cláudio A Bonjardim and Erna G Kroon
    Citation: Virology Journal 2009 6:47
    Content type: Case Report Published on:

  10. The association of human leukocyte antigen (HLA) genes with the outcome of hepatitis C virus (HCV) infection may be modified by ethnic and geographical differences.

    Authors: Jane H Wang, Xin Zheng, Xiaogang Ke, M Tevfik Dorak, Jingjing Shen, Basmattee Boodram, Maurice O'Gorman, Kenneth Beaman, Scott J Cotler, Ronald Hershow and Lijun Rong
    Citation: Virology Journal 2009 6:46
    Content type: Research Published on:

  11. Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parente...

    Authors: Peter D Burbelo, Alexandra T Issa, Kathryn H Ching, Maurice Exner, W Lawrence Drew, Harvey J Alter and Michael J Iadarola
    Citation: Virology Journal 2009 6:45
    Content type: Methodology Published on:

  12. Proteins associated with the late endosome (LE) appear to play a central role in the envelopment of a number of taxonomically diverse viruses. How viral proteins interact with LE-associated proteins to facilit...

    Authors: Yali Chen, Kady M Honeychurch, Guang Yang, Chelsea M Byrd, Chris Harver, Dennis E Hruby and Robert Jordan
    Citation: Virology Journal 2009 6:44
    Content type: Research Published on:

  14. Influenza epidemics continue to cause morbidity and mortality within the human population despite widespread vaccination efforts. This, along with the ominous threat of an avian influenza pandemic (H5N1), demo...

    Authors: Andrew S Herbert, Lynn Heffron, Roy Sundick and Paul C Roberts
    Citation: Virology Journal 2009 6:42
    Content type: Research Published on:

  15. Based upon whole genome and proteome analysis, Escherichia coli O157:H7-specific bacteriophage (phage) wV8 belongs to the new myoviral genus, "the Felix O1-like viruses" along with Salmonella phage Felix O1 and E...

    Authors: Andre Villegas, Yi-Min She, Andrew M Kropinski, Erika J Lingohr, Amanda Mazzocco, Shivani Ojha, Thomas E Waddell, Hans-Wolfgang Ackermann, Dianne M Moyles, Rafiq Ahmed and Roger P Johnson
    Citation: Virology Journal 2009 6:41
    Content type: Short report Published on:

  16. Herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases worldwide. The first time infection of the mother may lead to severe illness in pregnancy and may be associate...

    Authors: Elena Anzivino, Daniela Fioriti, Monica Mischitelli, Anna Bellizzi, Valentina Barucca, Fernanda Chiarini and Valeria Pietropaolo
    Citation: Virology Journal 2009 6:40
    Content type: Review Published on:

  17. Avian influenza virus H5N1 is a major concern as a potential global pandemic. It is thought that multiple key events must take place before efficient human-to-human transmission of the virus occurs. The first ...

    Authors: Ying Guo, Emily Rumschlag-Booms, Jizhen Wang, Haixia Xiao, Jia Yu, Jianwei Wang, Li Guo, George F Gao, Youjia Cao, Michael Caffrey and Lijun Rong
    Citation: Virology Journal 2009 6:39
    Content type: Research Published on:

  19. The increase in adamantine resistance in influenza A (H3N2) and the emergence of oseltamivir resistance in influenza A (H1N1) has necessitated the use of rapid methodologies to detect influenza subtype. The pu...

    Authors: Shelly Bolotin, Ernesto Lombos, Rani Yeung, AliReza Eshaghi, Joanne Blair and Steven J Drews
    Citation: Virology Journal 2009 6:37
    Content type: Short report Published on:

  20. We have characterised a new highly divergent geminivirus species, Eragrostis curvula streak virus (ECSV), found infecting a hardy perennial South African wild grass. ECSV represents a new genus-level geminivir...

    Authors: Arvind Varsani, Dionne N Shepherd, Kyle Dent, Aderito L Monjane, Edward P Rybicki and Darren P Martin
    Citation: Virology Journal 2009 6:36
    Content type: Research Published on:

  23. Semliki Forest virus (SFV) has a positive strand RNA genome and infects different cells of vertebrates and invertebrates. The 5' two-thirds of the genome encodes non-structural proteins that are required for v...

    Authors: Kai Rausalu, Anna Iofik, Liane Ülper, Liis Karo-Astover, Valeria Lulla and Andres Merits
    Citation: Virology Journal 2009 6:33
    Content type: Research Published on:

  25. Hepatitis delta virus (HDV) is a defected RNA virus and requires its encoded large antigen (LDAg) to interact with helper viral proteins (HBsAgs) during assembly. Recently, a study demonstrated a direct bindin...

    Authors: Yu-Cheng Wang, Chi-Ruei Huang, Mei Chao and Szecheng J Lo
    Citation: Virology Journal 2009 6:31
    Content type: Research Published on:

  27. Epstein-Barr virus is replicated once per cell-cycle, and partitioned equally in latently infected cells. Both these processes require a single viral cis- element, termed oriP, and a single viral protein, EBNA1. ...

    Authors: Ashok Aiyar, Siddhesh Aras, Amber Washington, Gyanendra Singh and Ronald B Luftig
    Citation: Virology Journal 2009 6:29
    Content type: Research Published on:

  28. The licensed smallpox vaccine, comprised of infectious vaccinia virus, has associated adverse effects, particularly for immunocompromised individuals. Therefore, safer DNA and protein vaccines are being invest...

    Authors: Kaori Shinoda, Linda S Wyatt, Kari R Irvine and Bernard Moss
    Citation: Virology Journal 2009 6:28
    Content type: Research Published on:

  29. Little is known about the detailed phylogeny relationships of CRF 02_AG HIV-1 polymerase genes in Ghana. The use of the protease gene of HIV-1 for subtyping has shown conflicting results.

    Authors: Kwamena W Sagoe, Magda Dwidar, Theophilus K Adiku and Max Q Arens
    Citation: Virology Journal 2009 6:27
    Content type: Research Published on:

  30. A focal H5N1 outbreak in poultry was reported from Manipur, a north-eastern state, of India, in 2007. The aim of this study was to genetically characterize the Manipur isolate to understand the relationship wi...

    Authors: Akhilesh C Mishra, Sarah S Cherian, Alok K Chakrabarti, Shailesh D Pawar, Santosh M Jadhav, Biswajoy Pal, Satish Raut, Santosh Koratkar and Sadhana S Kode
    Citation: Virology Journal 2009 6:26
    Content type: Research Published on:

  31. Systemic adenoviral (Ad) vector administration is associated with thrombocytopenia. Recently, Ad interaction with mouse platelets emerged as a key player determining liver uptake and platelet clearance. Howeve...

    Authors: Nilly Shimony, Gregory Elkin, Dror Kolodkin-Gal, Lina Krasny, Simcha Urieli-Shoval and Yosef S Haviv
    Citation: Virology Journal 2009 6:25
    Content type: Methodology Published on:

  32. In the present study, a genotype 4 HEV strain was identified in the fecal specimen from a seven months old infant with no symptom of hepatitis in Shanghai Children's hospital. The full capsid protein gene (ORF...

    Authors: Wen Zhang, Shixing Yang, Quan Shen, Junfeng Liu, Tongling Shan, Fen Huang, Huibo Ning, Yanjun Kang, Zhibiao Yang, Li Cui, Jianguo Zhu and Xiuguo Hua
    Citation: Virology Journal 2009 6:24
    Content type: Short report Published on:

  33. VPgs are viral proteins linked to the 5' end of some viral genomes. Interactions between several VPgs and eukaryotic translation initiation factors eIF4Es are critical for plant infection. However, VPgs are no...

    Authors: Eugénie Hébrard, Yannick Bessin, Thierry Michon, Sonia Longhi, Vladimir N Uversky, François Delalande, Alain Van Dorsselaer, Pedro Romero, Jocelyne Walter, Nathalie Declerck and Denis Fargette
    Citation: Virology Journal 2009 6:23
    Content type: Research Published on:

  34. Influenza viruses attach to cells via sialic acid receptors. The viral neuraminidase (NA) is needed to remove sialic acids so that newly budded virions can disperse. Known mechanisms of resistance to NA inhibi...

    Authors: Shelly Gulati, David F Smith and Gillian M Air
    Citation: Virology Journal 2009 6:22
    Content type: Research Published on:

  36. Rhesus macaques infected with lymphocytic choriomeningitis virus (LCMV) provide a model for human Lassa fever. Disease begins with flu-like symptoms and progresses rapidly with fatal consequences. Previously, ...

    Authors: Mahmoud Djavani, Oswald R Crasta, Yan Zhang, Juan Carlos Zapata, Bruno Sobral, Melissa G Lechner, Joseph Bryant, Harry Davis and Maria S Salvato
    Citation: Virology Journal 2009 6:20
    Content type: Research Published on:

  37. Previous studies indicate that the UL31 protein and its homology play similar roles in nuclear egress of all herpesviruses. However, there is no report on the UL31 gene product of DEV. In this study, we expressed...

    Authors: Wei Xie, Anchun Cheng, Mingshu Wang, Hua Chang, Dekang Zhu, Qihui Luo, Renyong Jia and Xiaoyue Chen
    Citation: Virology Journal 2009 6:19
    Content type: Research Published on:

  39. Gag protein from HIV-1 is a polyprotein of 55 kDa, which, during viral maturation, is cleaved to release matrix p17, core p24 and nucleocapsid proteins. The p24 antigen contains epitopes that prime helper CD4 ...

    Authors: Alberto J Donayre-Torres, Ernesto Esquivel-Soto, María deLourdes Gutiérrez-Xicoténcatl, Fernando R Esquivel-Guadarrama and Miguel A Gómez-Lim
    Citation: Virology Journal 2009 6:17
    Content type: Research Published on:

  40. Earlier, we detected viral RNAs packaged in the porcine adenovirus (PAdV) -3 virions. Using Southern blot analysis, we further demonstrated that the viral RNAs were predominantly packaged in CsCl purified matu...

    Authors: Li Xing and Suresh K Tikoo
    Citation: Virology Journal 2009 6:16
    Content type: Research Published on:

  41. Infectious bronchitis virus primarily induces a disease of the respiratory system, different IBV strains may show variable tissue tropisms and also affect the oviduct and the kidneys. Proventriculitis was also...

    Authors: Ahmed S Abdel-Moneim, Priscila Zlotowski, Jutta Veits, Günther M Keil and Jens P Teifke
    Citation: Virology Journal 2009 6:15
    Content type: Research Published on:

  42. Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expression strategy, resulting i...

    Authors: Andrew E Firth and John F Atkins
    Citation: Virology Journal 2009 6:14
    Content type: Short report Published on:

  43. HCV is circulating as a heterogeneous group of quasispecies. It has been addressed that siRNA can inhibit HCV replication in-vitro using HCV clone and/or replicon which have only one genotype. The current stud...

    Authors: Abdel Rahman N Zekri, Abeer A Bahnassy, Hanaa M Alam El-Din and Hosny M Salama
    Citation: Virology Journal 2009 6:13
    Content type: Research Published on:

  45. This study describes the prevalence of culture-positive adenovirus serotypes in culture-positive respiratory specimens sent to the Central Public Health Laboratory, Toronto, Ontario, Canada for the period Sept...

    Authors: Rani Yeung, AliReza Eshaghi, Ernesto Lombos, Joanne Blair, Tony Mazzulli, Laura Burton and Steven J Drews
    Citation: Virology Journal 2009 6:11
    Content type: Short report Published on:

  47. The UL97 kinase has been shown to phosphorylate and inactivate the retinoblastoma protein (Rb) and has three consensus Rb-binding motifs that might contribute to this activity. Recombinant viruses containing m...

    Authors: Rachel B Gill, Samuel L Frederick, Caroll B Hartline, Sunwen Chou and Mark N Prichard
    Citation: Virology Journal 2009 6:9
    Content type: Short report Published on:

  48. Various members of the mint family have been used historically in Chinese and Native American medicine. Many of these same family members, including Prunella vulgaris, have been reported to have anti-viral activi...

    Authors: Melinda A Brindley, Mark P Widrlechner, Joe-Ann McCoy, Patricia Murphy, Cathy Hauck, Ludmila Rizshsky, Basil Nikolau and Wendy Maury
    Citation: Virology Journal 2009 6:8
    Content type: Research Published on:

  49. Sci-B-Vac™ is a recombinant, hepatitis B vaccine derived from a mammalian cell line and containing hepatitis B surface antigen (HBsAg) as well as preS1 and preS2 antigens. Few studies have been performed on th...

    Authors: Ulla B Hellström, Kazimierz Madalinski and Staffan PE Sylvan
    Citation: Virology Journal 2009 6:7
    Content type: Research Published on:

  50. Affecting both livestock and humans, Rift Valley Fever is considered as one of the most important viral zoonoses in Africa. However, no licensed vaccines or effective treatments are yet available for human use...

    Authors: Nina Lagerqvist, Jonas Näslund, Åke Lundkvist, Michèle Bouloy, Clas Ahlm and Göran Bucht
    Citation: Virology Journal 2009 6:6
    Content type: Research Published on:
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  • ISSN: 1743-422X (electronic)

Virology Journal

ISSN: 1743-422X