Articles
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Citation: Virology Journal 2021 18:172
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Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo
Diallyl trisulfide (DATS) is a garlic-derived organosulfur compound. As it has been shown to have anti-viral activity, we hypothesized that it may alleviate infections caused by H9N2 avian influenza virus (AIV...
Citation: Virology Journal 2021 18:171 -
Mechanism of interaction between virus and host is inferred from the changes of gene expression in macrophages infected with African swine fever virus CN/GS/2018 strain
African swine fever virus (ASFV) is a highly lethal virus that can infect porcine alveolar macrophages (PAMs). Since ASFV, China has dealt with a heavy blow to the pig industry. However, the effect of infectio...
Citation: Virology Journal 2021 18:170 -
Cells of the human respiratory tract support the replication of pathogenic Old World orthohantavirus Puumala
Transmission of all known pathogenic orthohantaviruses (family Hantaviridae) usually occurs via inhalation of aerosols contaminated with viral particles derived from infected rodents and organ manifestation of in...
Citation: Virology Journal 2021 18:169 -
Circulating SARS-CoV-2 variants in Italy, October 2020–March 2021
A growing number of emerging SARS-CoV-2 variants is being identified worldwide, potentially impacting the effectiveness of current vaccines. We report the data obtained in several Italian regions involved in t...
Citation: Virology Journal 2021 18:168 -
First molecular characterization of poxviruses in cattle, sheep, and goats in Botswana
Poxviruses within the Capripoxvirus, Orthopoxvirus, and Parapoxvirus genera can infect livestock, with the two former having zoonotic importance. In addition, they induce similar clinical symptoms in common host ...
Citation: Virology Journal 2021 18:167 -
Evolutionary trajectory of SARS-CoV-2 and emerging variants
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 variants has generated renewed interest i...
Citation: Virology Journal 2021 18:166 -
Apoptotic investigation of brain tissue cells in dogs naturally infected by canine distemper virus
Canine distemper caused by canine distemper virus that belongs to the Morbillivirus genus of the Paramyxoviridae family is still a global epidemic significant infectious disease, especially in pet dogs in China a...
Citation: Virology Journal 2021 18:165 -
DNA aptamer against EV-A71 VP1 protein: selection and application
Enterovirus 71 (EV-A71) is a highly infectious pathogen associated with hand, foot and mouth disease, herpangina, and various neurological complications, so it is important for the early detection and treatmen...
Citation: Virology Journal 2021 18:164 -
Virome analysis of ticks in a forest region of Liaoning, China: characterization of a novel hepe-like virus sequence
Ticks (class Arachnida, subclass Acari) are vectors of transmitting a broad range of pathogenic microorganisms, protozoa, and viruses affecting humans and animals. Liaoning Province is rich in forests where diffe...
Citation: Virology Journal 2021 18:163 -
The spectrum of Epstein-Barr virus infections of the central nervous system after organ transplantation
Epstein-Barr virus (EBV)-related neurologic complications have a diverse presentation in transplant recipients, creating diagnostic and therapeutic challenges for clinicians. In this case series, we report uni...
Citation: Virology Journal 2021 18:162 -
In vitro antiviral activity of peptide-rich extracts from seven Nigerian plants against three non-polio enterovirus species C serotypes
As frequent viral outbreaks continue to pose threat to public health, the unavailability of antiviral drugs and challenges associated with vaccine development underscore the need for antiviral drugs discovery ...
Citation: Virology Journal 2021 18:161 -
First molecular detection of hepatitis E virus genome in camel and pig faecal samples in Ethiopia
Hepatitis E is an enteric and zoonotic disease caused by hepatitis E virus (HEV) that is mainly transmitted via the faecal-oral route through contaminated food or the environment. The virus is an emerging infe...
Citation: Virology Journal 2021 18:160 -
Impact of COVID-19 pandemic on the prevalence of respiratory viruses in children with lower respiratory tract infections in China
The multifaceted non-pharmaceutical interventions (NPIs) taken during the COVID-19 pandemic not only decrease the spreading of the SARS-CoV-2, but have impact on the prevalence of other viruses. This study aim...
Citation: Virology Journal 2021 18:159 -
Efficacy and safety of oncolytic viruses in advanced or metastatic cancer: a network meta-analysis
Oncolytic viruses (OVs) have shown prospects in advanced and metastatic cancer, and many clinical trials have been carried out. To compare OV therapies comprehensively and provide a categorized profile and ran...
Citation: Virology Journal 2021 18:158 -
Association of dyslipidemia with the severity and mortality of coronavirus disease 2019 (COVID-19): a meta-analysis
The numbers of confirmed cases of coronavirus disease 2019 (COVID-19) and COVID-19 related deaths are still increasing, so it is very important to determine the risk factors of COVID-19. Dyslipidemia is a comm...
Citation: Virology Journal 2021 18:157 -
Efficacy and safety of ledipasvir/sofosbuvir for hepatitis C among drug users: a systematic review and meta-analysis
Limited data is available on the efficacy of direct acting anti-viral drugs on hepatitis C in drug users. The aim of this meta-analysis was to comprehensively analyze the efficacy and safety of LDV/SOF in drug...
Citation: Virology Journal 2021 18:156 -
Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes
Citation: Virology Journal 2021 18:155 -
Keep out! SARS-CoV-2 entry inhibitors: their role and utility as COVID-19 therapeutics
The COVID-19 pandemic has put healthcare infrastructures and our social and economic lives under unprecedented strain. Effective solutions are needed to end the pandemic while significantly lessening its furth...
Citation: Virology Journal 2021 18:154 -
Genotyping of non-polio enteroviruses associated with acute flaccid paralysis in Thailand in 2013 and 2014
Acute flaccid paralysis (AFP) surveillance was conducted as part of the World Health Organization’s strategy for completely eradicating poliomyelitis and leaving non-polio enteroviruses NPEVs as one of the mai...
Citation: Virology Journal 2021 18:153 -
Lineage analysis of human papillomavirus type 39 in cervical samples of Iranian women
The data with regards to the regional variants of distinct HPV types is of great value. Accordance with this, this study aimed to investigate the sequence variations of E6 gene and long control region of HPV 3...
Citation: Virology Journal 2021 18:152 -
Construction of an infectious clone of Zika virus stably expressing an EGFP marker in a eukaryotic expression system
Zika virus is becoming one of the most widely transmitted arboviruses in the world. Development of antiviral inhibitor and vaccine requires an experimental system that allows rapid monitoring of the virus infe...
Citation: Virology Journal 2021 18:151 -
Molecular detection and identification of Culex flavivirus in mosquito species from Jeju, Republic of Korea
Mosquito-borne flaviviruses are prime pathogens and have been a major hazard to humans and animals. They comprise several arthropod-borne viruses, including dengue virus, yellow fever virus, Japanese encephali...
Citation: Virology Journal 2021 18:150 -
SARS-CoV-2: preliminary study of infected human nasopharyngeal tissue by high resolution microscopy
The novel coronavirus SARS-CoV-2 is the etiological agent of COVID-19. This virus has become one of the most dangerous in recent times with a very high rate of transmission. At present, several publications sh...
Citation: Virology Journal 2021 18:149 -
Further considerations about “Detection and identification of enteroviruses circulating in children with acute gastroenteritis in Pará State, Northern Brazil (2010–2011)”
On the detection and identification of enteroviruses circulating in children with acute gastroenteritis in Brazil: reply to Luchs, A. Comments on Detection and identification of enteroviruses circulating in ch...
Citation: Virology Journal 2021 18:148 -
Clinical and virological course of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center cohort study
The clinical and virological course of patients with coronavirus disease 2019 (COVID-19) are lacking. We aimed to describe the clinical and virological characteristics of COVID-19 patients from 10 designated h...
Citation: Virology Journal 2021 18:147 -
Fluorescence of ocular surface in a Covid -19 patient after Favipiravir treatment: a case report
Favipiravir is used in treatment of Covid-19 patients. We aimed to share of ocular surface fluorescence in a patient after Favipiravir treatment in this case report.
Citation: Virology Journal 2021 18:146 -
Prevalence and clinical correlation of hepatitis E virus antibody in the patients’ serum samples from a tertiary care hospital in Thailand during 2015–2018
Prevalence and incidence of hepatitis caused by HEV infection are usually higher in developing countries. This study demonstrated the HEV seroprevalence and incidence of HEV infection in patients with clinical...
Citation: Virology Journal 2021 18:145 -
The prevalence of human herpesvirus 8 in normal, premalignant, and malignant cervical samples of Iranian women
Regard to this fact that the main transmission route of HPV and HHV-8 is via sexual activity, it is reasonable to speculate that coinfection of HPV and HHV-8 may have been played an important role in the devel...
Citation: Virology Journal 2021 18:144 -
Plant responses to geminivirus infection: guardians of the plant immunity
Geminiviruses are circular, single-stranded viruses responsible for enormous crop loss worldwide. Rapid expansion of geminivirus diversity outweighs the continuous effort to control its spread. Geminiviruses c...
Citation: Virology Journal 2021 18:143 -
Antiviral drugs arbidol and interferon alpha-1b contribute to reducing the severity of COVID-19 patients: a retrospective cohort study
The aim of this study was to evaluate the role of antiviral drugs in reducing the risk of developing severe illness in patients with moderate COVID-19 pneumonia.
Citation: Virology Journal 2021 18:142 -
Hepatitis E virus prevalence among blood donors in Dali, China
Hepatitis E virus (HEV) is a nonenveloped RNA virus causing hepatitis E worldwide. The increase in transfusion-transmitted cases of HEV infections from asymptomatic blood donors causing serious illnesses among...
Citation: Virology Journal 2021 18:141 -
Correction to: Transmission of H7N9 influenza virus in mice by different infective routes
Citation: Virology Journal 2021 18:140 -
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins
Approximately 15% of human cancers are attributed to viruses. Numerous studies have shown that high-risk human polyomaviruses (HR-HPV) and Merkel cell polyomavirus (MCPyV) are two human tumor viruses associate...
Citation: Virology Journal 2021 18:139 -
Transmission frequency of COVID-19 through pre-symptomatic and asymptomatic patients in AJK: a report of 201 cases
The COVID-19 pandemic is a catastrophic global phenomenon, affecting human life in a way unseen since the 1918 influenza pandemic. Effective management of this threat requires halting transmission, a strategy ...
Citation: Virology Journal 2021 18:138 -
A study based on four immunoassays: Hepatitis C virus antibody against different antigens may have unequal contributions to detection
All commercial Hepatitis C virus antibody (anti-HCV) assays use a combination of recombinant antigens to detect antibody response. Antibody responses to individual antigenic regions (core, NS3/4 and NS5) used ...
Citation: Virology Journal 2021 18:137 -
The key amino acids of E protein involved in early flavivirus infection: viral entry
Flaviviruses are enveloped viruses that infect multiple hosts. Envelope proteins are the outermost proteins in the structure of flaviviruses and mediate viral infection. Studies indicate that flaviviruses main...
Citation: Virology Journal 2021 18:136 -
Is there a relationship between psoriasis and hepatitis C? A meta-analysis and bioinformatics investigation
The relationship between psoriasis and hepatitis C was previously controversial, so our purpose is to investigate this connection.
Citation: Virology Journal 2021 18:135 -
Persistence of SARS-CoV-2 RNA in the nasopharyngeal, blood, urine, and stool samples of patients with COVID-19: a hospital-based longitudinal study
The persistence of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) RNA in the body fluids of patients with the novel coronavirus disease 2019 (COVID-19) may increase the potential risk of viral tr...
Citation: Virology Journal 2021 18:134 -
Comments on “Detection and identification of enteroviruses circulating in children with acute gastroenteritis in Pará State, Northern Brazil (2010–2011)”
Investigation of human enterovirus (EV) in diarrheic fecal specimens is valuable to address EV diversity circulating worldwide. However, the detection of EV strains exclusively in fecal specimens must be inter...
Citation: Virology Journal 2021 18:133 -
Relationship between polymorphism of receptor SCARB2 gene and clinical severity of enterovirus-71 associated hand-foot-mouth disease
To investigate the relationship between polymorphism of scavenger receptor class B member 2 (SCARB2) gene and clinical severity of enterovirus (EV)-71 associated hand-foot-mouth disease (HFMD).
Citation: Virology Journal 2021 18:132 -
One-step real-time multiplex reverse transcription-polymerase chain reaction assay with melt curve analysis for detection of potato leafroll virus, potato virus S, potato virus X, and potato virus Y
Certification of seed potato as free of viruses is essential for stable potato production. Among more than 30 virus species infecting potato, potato leafroll virus (PLRV), potato virus S (PVS), potato virus X ...
Citation: Virology Journal 2021 18:131 -
Impact of joint management of a COVID-19 mother and her newborn on the virus transmission: a case report
Since last year, COVID-19, the disease caused by the novel Sars-Cov-2 virus, has been globally spread to all the world. COVID-19 infection among pregnant women has been described. However, transplacental trans...
Citation: Virology Journal 2021 18:130 -
Efficient translation of Eggplant mottled dwarf nucleorhabdovirus N and X genes requires both 5′ and 3′ UTRs
Circularization of RNA mediated by association of translation factors and RNA elements in 5′ and 3′ UTRs is a common feature for translation control in eukaryotes. There is no information about translation in ...
Citation: Virology Journal 2021 18:129 -
Correction to: In vitro and in vivo analyses of co‑infections with peste des petits ruminants and capripox vaccine strains
An amendment to this paper has been published and can be accessed via the original article.
Citation: Virology Journal 2021 18:128 -
Influenza co-infection associated with severity and mortality in COVID-19 patients
In COVID-19 patients, undetected co-infections may have severe clinical implications associated with increased hospitalization, varied treatment approaches and mortality. Therefore, we investigated the implica...
Citation: Virology Journal 2021 18:127 -
Viral loads, lymphocyte subsets and cytokines in asymptomatic, mildly and critical symptomatic patients with SARS-CoV-2 infection: a retrospective study
Tens of million cases of coronavirus disease-2019 (COVID-19) have occurred globally. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attacks the respiratory system, causing pneumonia and lymph...
Citation: Virology Journal 2021 18:126 -
Identification and characterization of lncRNA AP000253 in occult hepatitis B virus infection
Recent studies suggest that lncRNAs may play significant roles in the development of hepatitis B virus (HBV) infection. However, as a special stage of HBV infection, the lncRNA expression in occult HBV infecti...
Citation: Virology Journal 2021 18:125 -
Simple rapid in vitro screening method for SARS-CoV-2 anti-virals that identifies potential cytomorbidity-associated false positives
The international SARS-CoV-2 pandemic has resulted in an urgent need to identify new anti-viral drugs for treatment of COVID-19. The initial step to identifying potential candidates usually involves in vitro s...
Citation: Virology Journal 2021 18:123 -
Virome of respiratory secretion from children with unknown etiological acute respiratory disease revealed recombinant human parechovirus and other significant viruses
Using viral metagenomics, viral nucleic acid in 30 respiratory secretion samples collected from children with unknown etiological acute respiratory disease were investigated. Sequences showing similarity to hu...
Citation: Virology Journal 2021 18:122
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- ISSN: 1743-422X (electronic)