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  1. Bovine viral diarrhea virus (BVDV) is the prototype representative of the pestivirus genus in the Flaviviridae family. It has been shown that the initiation of translation of BVDV RNA occurs by an internal riboso...

    Authors: Lorin Moes and Manfred Wirth
    Citation: Virology Journal 2007 4:124
  2. Mechanisms by which HIV-1 mediates reductions in CD4+ cell levels in infected persons are being intensely investigated, and have broad implications for AIDS drug and vaccine development. Virally induced change...

    Authors: Joshua M Costin, Joshua M Rausch, Robert F Garry and William C Wimley
    Citation: Virology Journal 2007 4:123
  3. According to the World Reference Laboratory for FMD, a new subtype of FMDV serotype A was detected in Iran in 2005. This subtype was designated A/IRN/2005, and rapidly spread throughout Iran and moved westward...

    Authors: Joern Klein, Manzoor Hussain, Munir Ahmad, Preben Normann, Muhammad Afzal and Soren Alexandersen
    Citation: Virology Journal 2007 4:122
  4. The HSV-1 UL20 protein (UL20p) and glycoprotein K (gK) are both important determinants of cytoplasmic virion morphogenesis and virus-induced cell fusion. In this manuscript, we examined the effect of UL20 muta...

    Authors: Jeffrey M Melancon, Preston A Fulmer and Konstantin G Kousoulas
    Citation: Virology Journal 2007 4:120
  5. This is a retraction of the article submitted by Zhang et al. Virology J 2007, 4:92

    Authors: Qingrun Zhang, Guanghua Wu, Elliott Richards, Shan'gang Jia and Changqing Zeng
    Citation: Virology Journal 2007 4:119

    The original article was published in Virology Journal 2007 4:92

  6. The M2 ectodomain (M2e) of influenza A virus (IAV) strains that have circulated in humans during the past 90 years shows remarkably little structural diversity. Since M2e-specific antibodies (Abs) are capable ...

    Authors: Krystyna Mozdzanowska, Darya Zharikova, Mare Cudic, Laszlo Otvos and Walter Gerhard
    Citation: Virology Journal 2007 4:118
  7. HBV remains one of the major pathogens of liver diseases but the outcomes as inflammation, cirrhosis and cancer of the liver are greatly related to different viral genotypes. The aim of this study was to asses...

    Authors: Yi Wei Lu, Tuan Lin Tan, Jianhua Zhang and Wei Ning Chen
    Citation: Virology Journal 2007 4:117
  8. The human papillomavirus type 16 E5 protein (HPV16 E5) down-regulates surface expression of HLA-I molecules. The molecular mechanisms underlying this effect are so far unknown. Here we show that HPV16 E5 down-...

    Authors: Myriam Gruener, Ignacio G Bravo, Frank Momburg, Angel Alonso and Pascal Tomakidi
    Citation: Virology Journal 2007 4:116
  9. The yellow fever virus, a member of the genus Flavivirus, is an arthropod-borne pathogen causing severe disease in humans. The attenuated yellow fever 17D virus strain has been used for human vaccination for 70 y...

    Authors: Myrna C Bonaldo, Samanta M Mello, Gisela F Trindade, Aymara A Rangel, Adriana S Duarte, Prisciliana J Oliveira, Marcos S Freire, Claire F Kubelka and Ricardo Galler
    Citation: Virology Journal 2007 4:115
  10. More than 20 years ago, hantaviral antigens were reported in tissues of the Eurasian common shrew (Sorex araneus), Eurasian water shrew (Neomys fodiens) and common mole (Talpa europea), suggesting that insectivor...

    Authors: Jin-Won Song, Se Hun Gu, Shannon N Bennett, Satoru Arai, Maria Puorger, Monika Hilbe and Richard Yanagihara
    Citation: Virology Journal 2007 4:114
  11. A DNA mirror repeat is a sequence segment delimited on the basis of its containing a center of symmetry on a single strand, e.g. 5'-GCATGGTACG-3'. It is most frequently described in association with a function...

    Authors: Dorothy M Lang
    Citation: Virology Journal 2007 4:113
  12. A human papillomavirus (HPV) virion is composed of capsid proteins L1 and L2. Several cysteine residues are located on L1 of various HPVs at markedly similar relative positions, suggesting their important func...

    Authors: Yoshiyuki Ishii, Kazunari Kondo, Tamae Matsumoto, Keiko Tanaka, Fumiko Shinkai-Ouchi, Ken'ichi Hagiwara and Tadahito Kanda
    Citation: Virology Journal 2007 4:110
  13. Motavizumab (MEDI-524) is a monoclonal antibody with enhanced neutralizing activity against RSV. In mice, motavizumab suppressed RSV replication which resulted in significant reduction of clinical parameters o...

    Authors: Asunción Mejías, Susana Chávez-Bueno, Martin B Raynor, John Connolly, Peter A Kiener, Hasan S Jafri and Octavio Ramilo
    Citation: Virology Journal 2007 4:109
  14. The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MA...

    Authors: Kelly L Warfield, Derron A Alves, Steven B Bradfute, Daniel K Reed, Sean VanTongeren, Warren V Kalina, Gene G Olinger and Sina Bavari
    Citation: Virology Journal 2007 4:108
  15. Here we investigated the nature and functional consequences of mutations in the HIV-1 tat gene within an epidemiologically-linked AIDS transmission cohort consisting of a non-progressing donor (A) and two normal ...

    Authors: Haran Sivakumaran, Bin Wang, M John Gill, Brenda Beckholdt, Nitin K Saksena and David Harrich
    Citation: Virology Journal 2007 4:107
  16. We have developed a system that isolates and replicates HCV in vitro. These isolates are called CIMM-HCV. This system has made it possible to analyze the biology, nature, and extent of HCV variability, among othe...

    Authors: S Zaki Salahuddin, Katherine A Snyder, Andre Godwin, Renu Grewal, John G Prichard, Ann S Kelley and Dennis Revie
    Citation: Virology Journal 2007 4:106
  17. The nucleoprotein (NP) of Marburg virus (MARV) is responsible for the encapsidation of viral genomic RNA and the formation of the helical nucleocapsid precursors that accumulate in intracellular inclusions in ...

    Authors: Andrea DiCarlo, Peggy Möller, Angelika Lander, Larissa Kolesnikova and Stephan Becker
    Citation: Virology Journal 2007 4:105
  18. The epidemiology of viral hepatitis during pregnancy is essential for health planners and programme managers. While much data exist concerning viral hepatitis during pregnancy in many African countries, no pro...

    Authors: Rasha M Elsheikh, Ahmed A Daak, Mohamed A Elsheikh, Mubarak S Karsany and Ishag Adam
    Citation: Virology Journal 2007 4:104
  19. Human adenovirus serotype 5 (Ad5) has been widely explored as a gene delivery vector for a variety of diseases. Many target cells, however, express low levels of Ad5 native receptor, the Coxsackie-Adenovirus R...

    Authors: Tie Han, Yizhe Tang, Hideyo Ugai, Leslie E Perry, Gene P Siegal, Juan L Contreras and Hongju Wu
    Citation: Virology Journal 2007 4:103
  20. Viruses that are incorporating host cell proteins might trigger autoimmune diseases. It is therefore of interest to identify possible host proteins associated with viruses, especially for enveloped viruses tha...

    Authors: Maria Hammarstedt, Jenny Ahlqvist, Steven Jacobson, Henrik Garoff and Anna Fogdell-Hahn
    Citation: Virology Journal 2007 4:101
  21. The human immunodeficiency virus type 1 (HIV-1) has been intensely investigated since its discovery in 1983 as the cause of acquired immune deficiency syndrome (AIDS). With relatively few proteins made by the ...

    Authors: Joshua M Costin
    Citation: Virology Journal 2007 4:100
  22. The adeno-associated virus (AAV) has rapidly gained popularity in gene therapy since the establishment of the first AAV2 infectious clone, in 1982, due to some of their distinguishing characteristics such as l...

    Authors: Renata dosSantos Coura and Nance Beyer Nardi
    Citation: Virology Journal 2007 4:99

    The Erratum to this article has been published in Virology Journal 2010 7:12

  23. Genotype 4 hepatitis E virus (HEV) was reportedly transmitted freely between humans and swine in eastern China. The full-length genomic sequence of Shanghai swine isolate (SH-SW-zs1) recovered from feces sampl...

    Authors: Quan Shen, Wen Zhang, Xiangrong Cao, Jing Mou, Li Cui and Xiuguo Hua
    Citation: Virology Journal 2007 4:98
  24. The recently sequenced 218 kb genome of morphologically atypical Bacillus thuringiensis phage 0305φ8-36 exhibited only limited detectable homology to known bacteriophages. The only known relative of this phage is...

    Authors: Stephen C Hardies, Julie A Thomas and Philip Serwer
    Citation: Virology Journal 2007 4:97
  25. Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is the predominant species of domestic rabbit throughout t...

    Authors: Michael T McIntosh, Shawn C Behan, Fawzi M Mohamed, Zhiqiang Lu, Karen E Moran, Thomas G Burrage, John G Neilan, Gordon B Ward, Giuliana Botti, Lorenzo Capucci and Samia A Metwally
    Citation: Virology Journal 2007 4:96
  26. Natural multiple viral infections of cultivated cowpeas have been reported in Nigeria. In this study, three Nigerian commercial cowpea cultivars ("Olo 11", "Oloyin" and "White") and two lines from the IITA (IT...

    Authors: Moni A Taiwo, Kehinde T Kareem, Imade Y Nsa and Jackies D'A Hughes
    Citation: Virology Journal 2007 4:95
  27. Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species. However, there is very little information ...

    Authors: Béatrice Pignolet, Jean-Luc Duteyrat, Aude Allemandou, Jacqueline Gelfi, Gilles Foucras and Stéphane Bertagnoli
    Citation: Virology Journal 2007 4:94
  28. Hepatitis B virus (HBV) infection is a serious health problem worldwide. Treatment recommendation and response are mainly indicated by viral load, e antigen (HBeAg) seroconversion, and ALT levels. The S antige...

    Authors: Min Lian, Xu Zhou, Lai Wei, Shihong Qiu, Tong Zhou, Lanfen Li, Xiaocheng Gu, Ming Luo and Xiaofeng Zheng
    Citation: Virology Journal 2007 4:93
  29. The highly heterogenic characteristic of viruses is the major obstacle to efficient DNA amplification. Taking advantage of the large number of virus DNA sequences in public databases to select conserved sites ...

    Authors: Qingrun Zhang, Guanghua Wu, Elliott Richards, Shan'gang Jia and Changqing Zeng
    Citation: Virology Journal 2007 4:92

    The Retraction Note to this article has been published in Virology Journal 2007 4:119

  30. Dengue and Dengue hemorrhagic fever have emerged as some of the most important mosquito-borne viral diseases in the tropics. The mechanisms of pathogenesis of Dengue remain elusive. Recently, virus-induced apo...

    Authors: Indira Umareddy, Olivier Pluquet, Qing Yin Wang, Subhash G Vasudevan, Eric Chevet and Feng Gu
    Citation: Virology Journal 2007 4:91
  31. The genetic characterization of wild-type measles strains isolated during an epidemic cluster of measles occurred in Puglia (South Italy), between November 2006 and January 2007, was performed. Measles virus (...

    Authors: Maria Chironna, Rosa Prato, Anna Sallustio, Domenico Martinelli, Cinzia Germinario, Pierluigi Lopalco and Michele Quarto
    Citation: Virology Journal 2007 4:90
  32. Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The ...

    Authors: Sidhartha Hazari, Lizeth Taylor, Salima Haque, Robert F Garry, Sander Florman, Ronald Luftig, Frederic Regenstein and Srikanta Dash
    Citation: Virology Journal 2007 4:89
  33. Endothelial cells are a target for gene therapy because they are implicated in a number of vascular diseases. Recombinant baculovirus have emerged as novel gene delivery vectors. However, there is no informati...

    Authors: Agustín Luz-Madrigal, Carmen Clapp, Jorge Aranda and Luis Vaca
    Citation: Virology Journal 2007 4:88
  34. Kaposi's sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a highly vascularized neoplasm characterized by endothelial-derived spindle-shaped tumor cells. KSHV-infected mic...

    Authors: Bryan D Shelby, Heather L LaMarca, Harris E McFerrin, Anne B Nelson, Joseph A Lasky, Gang Sun, Leslie Myatt, Margaret K Offermann, Cindy A Morris and Deborah E Sullivan
    Citation: Virology Journal 2007 4:87
  35. Noroviruses are the most common cause of non-bacterial gastroenteritis. Improved detection methods have seen a large increase in the number of human NoV genotypes in the last ten years. The objective of this s...

    Authors: John F Menton, Karen Kearney and John G Morgan
    Citation: Virology Journal 2007 4:86
  36. HTLV-I infected CD4+ T-cells lines usually progress towards a CD3- or CD3low phenotype. In this paper, we studied expression, kinetics, chromatin remodeling of the CD3 gene at different time-points post HTLV-I in...

    Authors: Haidar Akl, Bassam Badran, Gratiela Dobirta, Germain Manfouo-Foutsop, Maria Moschitta, Makram Merimi, Arsène Burny, Philippe Martiat and Karen E Willard-Gallo
    Citation: Virology Journal 2007 4:85
  37. Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often ...

    Authors: Sandra Prepens, Karl-Anton Kreuzer, Fabian Leendertz, Andreas Nitsche and Bernhard Ehlers
    Citation: Virology Journal 2007 4:84
  38. Japanese encephalitis virus (JEV) is a member of mosquito-borne Flaviviridae. To date, the mechanisms of the early events of JEV infection remain poorly understood, and the cellular receptors are unidentified. Th...

    Authors: Junping Ren, Tianbing Ding, Wei Zhang, Jianhua Song and Wenyu Ma
    Citation: Virology Journal 2007 4:83
  39. Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression ...

    Authors: Rasha Hammamieh, Mohsen Barmada, George Ludwig, Sheila Peel, Nick Koterski and Marti Jett
    Citation: Virology Journal 2007 4:82
  40. The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein ess...

    Authors: Amjad Hussain, Suman R Das, Charu Tanwar and Shahid Jameel
    Citation: Virology Journal 2007 4:81
  41. Thottapalayam (TPM) virus belongs to the genus Hantavirus, family Bunyaviridae. The genomes of hantaviruses consist of three negative-stranded RNA segments (S, M and L) encoding the virus nucleocapsid (N), glycop...

    Authors: Pragya D Yadav, Martin J Vincent and Stuart T Nichol
    Citation: Virology Journal 2007 4:80
  42. Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. Previous and recent studies have suggested a diversification of type ...

    Authors: Gonzalo Moratorio, Mariela Martínez, María F Gutiérrez, Katiuska González, Rodney Colina, Fernando López-Tort, Lilia López, Ricardo Recarey, Alejandro G Schijman, María P Moreno, Laura García-Aguirre, Aura R Manascero and Juan Cristina
    Citation: Virology Journal 2007 4:79
  43. In 2005 huge epizooty of H5N1 HPAI occurred in Russia. It had been clear that territory of Russia becoming endemic for H5N1 HPAI. In 2006 several outbreaks have occurred. To develop new vaccines and antiviral ...

    Authors: Vasily A Evseenko, Eugeny K Bukin, Anna V Zaykovskaya, Kirill A Sharshov, Vladimir A Ternovoi, George M Ignatyev and Alexander M Shestopalov
    Citation: Virology Journal 2007 4:77
  44. Profilins are critical to cytoskeletal dynamics in eukaryotes; however, little is known about their viral counterparts. In this study, a poxviral profilin homolog, ectromelia virus strain Moscow gene 141 (ECTV...

    Authors: Christine Butler-Cole, Mary J Wagner, Melissa Da Silva, Gordon D Brown, Robert D Burke and Chris Upton
    Citation: Virology Journal 2007 4:76
  45. The Sydney blood bank cohort (SBBC) of long-term survivors consists of multiple individuals infected with attenuated, nef-deleted variants of human immunodeficiency virus type 1 (HIV-1) acquired from a single sou...

    Authors: Lachlan Gray, Melissa J Churchill, Jasminka Sterjovski, Kristie Witlox, Jennifer C Learmont, John S Sullivan, Steven L Wesselingh, Dana Gabuzda, Anthony L Cunningham, Dale A McPhee and Paul R Gorry
    Citation: Virology Journal 2007 4:75