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  1. Human herpesvirus-6 (HHV-6) can infect blood cells and thereby may inhibit hematopoietic stem and progenitor cell expansion and differentiation. In this context, it has been discussed if early progenitor cells...

    Authors: Stefanie Thulke, Aleksandar Radonić, Andreas Nitsche and Wolfgang Siegert
    Citation: Virology Journal 2006 3:77
  2. Epithelial defensins including human β-defensins (hBDs) and α-defensins (HDs) are antimicrobial peptides that play important roles in the mucosal defense system. However, the role of defensins in papillomaviru...

    Authors: Kong T Chong, Liangbin Xiang, Xiaohong Wang, Eunjoo L Jun, Long-fu Xi and John M Schweinfurth
    Citation: Virology Journal 2006 3:75
  3. Simian-Human immunodeficiency virus is a chimeric virus which, in rhesus macaques (Macacca mulatta) closely imitates immunodeficiency virus infection in human (HIV). A relatively new way to study pathogenesis of ...

    Authors: Erica E Carroll, Rasha Hammamieh, Nabarun Chakraborty, Aaron T Phillips, Stacy-Ann M Miller and Marti Jett
    Citation: Virology Journal 2006 3:74
  4. Sixty one tissue samples from several rodent species trapped in five provinces of Thailand were examined for the presence of hantaviral markers by enzyme-immunoassay and immunoblotting. Four samples, all from ...

    Authors: Jean-Pierre Hugot, Angelina Plyusnina, Vincent Herbreteau, Kirill Nemirov, Juha Laakkonen, Åke Lundkvist, Yupin Supputamongkol, Heikki Henttonen and Alexander Plyusnin
    Citation: Virology Journal 2006 3:72
  5. There is an urgent need to develop novel approaches to vaccination against the emerging, highly pathogenic avian influenza viruses. Here, we engineered influenza viral-like particles (Flu-VLPs) derived from re...

    Authors: Judit Szécsi, Bertrand Boson, Per Johnsson, Pia Dupeyrot-Lacas, Mikhail Matrosovich, Hans-Dieter Klenk, David Klatzmann, Viktor Volchkov and François-Loïc Cosset
    Citation: Virology Journal 2006 3:70
  6. There is widespread interest in the use of innate immune modulators as a defense strategy against infectious pathogens. Using rotavirus as a model system, we developed a cell-based, moderate-throughput screeni...

    Authors: Mark E Shaneyfelt, Anna D Burke, Joel W Graff, Mark A Jutila and Michele E Hardy
    Citation: Virology Journal 2006 3:68
  7. The performance of polyclonal monospecific rabbit anti-sera raised against synthetic peptides derived from conserved HCV sequences of genotype 4 was evaluated for efficient detection of viral core and E1 antig...

    Authors: Mostafa K El Awady, Yasmine S El Abd, Hussein A Shoeb, Ashraf A Tabll, AlaaElDin MS Hosny, Reem M El Shenawy, Khaled Atef, Noha G Bader El Din and Mahmoud M Bahgat
    Citation: Virology Journal 2006 3:67
  8. Hepatitis C virus (HCV) encodes several proteins that interfere with the host cell antiviral response. Previously, the serine protease NS3/4A was shown to inhibit IFN-β gene expression by blocking dsRNA-activa...

    Authors: Pasi Kaukinen, Maarit Sillanpää, Sergei Kotenko, Rongtuan Lin, John Hiscott, Krister Melén and Ilkka Julkunen
    Citation: Virology Journal 2006 3:66
  9. Emergence of viral variants that escape CTL control is a major hurdle in HIV vaccination unless such variants affect gene regions that are essential for virus replication. Vaccine-induced multispecific CTL cou...

    Authors: Pascale Villefroy, Franck Letourneur, Zoe Coutsinos, Lorenzo Mortara, Christian Beyer, Helene Gras-Masse, Jean-Gerard Guillet and Isabelle Bourgault-Villada
    Citation: Virology Journal 2006 3:65
  10. Plaque assays in cell culture monolayers under solid or semisolid overlay media are commonly used for quantification of viruses and antiviral substances. To overcome the pitfalls of known overlays, we tested s...

    Authors: Mikhail Matrosovich, Tatyana Matrosovich, Wolfgang Garten and Hans-Dieter Klenk
    Citation: Virology Journal 2006 3:63
  11. It was reported that elevation of the intracellular concentration of free Ca2+ ([Ca2+]i) by a calcium ionophore increased the release of herpes simplex virus type 1 (HSV-1). Freely diffusible hydrogen peroxide (H

    Authors: Emiko Arimoto, Soichi Iwai, Tetsuro Sumi, Yuzo Ogawa and Yoshiaki Yura
    Citation: Virology Journal 2006 3:62
  12. Guards of Cyprian honey bee colonies, Apis mellifera cypria, display a great defensive behaviour against hornets' attacks. The deformed wing virus (DWV) and the kakugo virus (KV) genomes are very similar, but unl...

    Authors: Agnès Rortais, Diana Tentcheva, Alexandros Papachristoforou, Laurent Gauthier, Gérard Arnold, Marc Edouard Colin and Max Bergoin
    Citation: Virology Journal 2006 3:61
  13. The amino terminal half of the cellular prion protein PrPc is implicated in both the binding of copper ions and the conformational changes that lead to disease but has no defined structure. However, as some struc...

    Authors: Snezana Vasiljevic, Junyuan Ren, YongXiu Yao, Kevin Dalton, Catherine S Adamson and Ian M Jones
    Citation: Virology Journal 2006 3:59
  14. The RNA-dependent RNA polymerase of Influenza A virus is a determinant of viral pathogenicity and host range that is responsible for transcribing and replicating the negative sense segmented viral genome (vRNA...

    Authors: Rosa M Dalton, Anne E Mullin, Maria Joao Amorim, Elizabeth Medcalf, Laurence S Tiley and Paul Digard
    Citation: Virology Journal 2006 3:58
  15. Characterization of the structural morphology of virus particles in electron micrographs is a complex task, but desirable in connection with investigation of the maturation process and detection of changes in ...

    Authors: Martin Ryner, Jan-Olov Strömberg, Cecilia Söderberg-Nauclér and Mohammed Homman-Loudiyi
    Citation: Virology Journal 2006 3:57
  16. Dengue virus infection has recently taken endemic proportion in India implicating all the four known dengue serotypes. There was a major dengue outbreak in northern India including Delhi in October- December, ...

    Authors: Paban Kumar Dash, Man Mohan Parida, Parag Saxena, Ajay Abhyankar, CP Singh, KN Tewari, Asha Mukul Jana, K Sekhar and PV Lakshmana Rao
    Citation: Virology Journal 2006 3:55
  17. Some individuals repeatedly exposed to Human Immunodeficiency Virus do not seroconvert and are resistant to HIV infection. Here, in a pediatric cohort of HIV seronegative infants born of HIV-infected mothers, ...

    Authors: Vázquez Pérez JA, Basualdo Sigales MC, Reyes-Terán G, Gudiño Rosales JC and Soler Claudín C
    Citation: Virology Journal 2006 3:52
  18. In the molecular world, researchers act as detectives working hard to unravel the mysteries surrounding cells. One of the researchers' greatest tools in this endeavor has been Raman spectroscopy. Raman spectro...

    Authors: Phelps J Lambert, Audy G Whitman, Ossie F Dyson and Shaw M Akula
    Citation: Virology Journal 2006 3:51
  19. There has been a recent resurgent interest in bacteriophage biology. Research was initiated to examine Campylobacter jejuni-specific bacteriophage in the Russian Federation to develop alternative control measures...

    Authors: EL Zhilenkov, VM Popova, DV Popov, LY Zavalsky, EA Svetoch, NJ Stern and BS Seal
    Citation: Virology Journal 2006 3:50
  20. Subacute sclerosing panencephalitis (SSPE) is a rare, slowly progressive neurological disorder caused by the persistent infection with measles virus (MV). Despite much research into SSPE, its pathology remains...

    Authors: M Kühne Simmonds, DWG Brown and L Jin
    Citation: Virology Journal 2006 3:49
  21. The abundance and the conservation of the repeated element (rep) genes in Ichnoviruses genomes suggest that this gene family plays an important role in viral cycles. In the Ichnovirus associated with the wasp Hyp...

    Authors: L Galibert, G Devauchelle, F Cousserans, J Rocher, P Cérutti, M Barat-Houari, P Fournier and AN Volkoff
    Citation: Virology Journal 2006 3:48
  22. Nipah virus is a zoonotic virus isolated from an outbreak in Malaysia in 1998. The virus causes infections in humans, pigs, and several other domestic animals. It has also been isolated from fruit bats. The pa...

    Authors: Li-Yen Chang, AR Mohd Ali, Sharifah Syed Hassan and Sazaly AbuBakar
    Citation: Virology Journal 2006 3:47
  23. A review of Pap smear diagnoses from a reference laboratory in Grand Forks, North Dakota over a 3-year period (07/00 to 10/03) revealed a two-fold higher rate of high grade squamous intraepithelial lesion in a...

    Authors: Lata Balakrishnan, Ryan Clauson, Timothy Weiland, Michelle Bianco and Barry Milavetz
    Citation: Virology Journal 2006 3:46
  24. Recent studies have shown that gamma interferon (IFN-γ) synergizes with IFN-α/β to inhibit herpes simplex virus type 1 (HSV-1) replication in vitro. Since IFN response represents an early host defense event again...

    Authors: Erina Petrera and Celia E Coto
    Citation: Virology Journal 2006 3:45
  25. The herpes simplex virus type 1 (HSV-1) ICP0 protein is an E3 ubiquitin ligase, which is encoded within the HSV-1 latency-associated locus. When ICP0 is not synthesized, the HSV-1 genome is acutely susceptible...

    Authors: William P Halford, Carla Weisend, Jennifer Grace, Mark Soboleski, Daniel JJ Carr, John W Balliet, Yumi Imai, Todd P Margolis and Bryan M Gebhardt
    Citation: Virology Journal 2006 3:44
  26. The Epstein-Barr virus (EBV) is associated with lymphoid malignancies, including Burkitt's lymphoma (BL), and can transform human B cells in vitro. EBV-harboring cell lines are widely used to investigate lymph...

    Authors: Michele Bernasconi, Christoph Berger, Jürg A Sigrist, Athos Bonanomi, Jens Sobek, Felix K Niggli and David Nadal
    Citation: Virology Journal 2006 3:43
  27. Lassa virus glycoprotein is synthesised as a precursor (preGP-C) into the lumen of the endoplasmic reticulum. After cotranslational cleavage of the signal peptide, the immature GP-C is posttranslationally proc...

    Authors: Robert Eichler, Oliver Lenz, Wolfgang Garten and Thomas Strecker
    Citation: Virology Journal 2006 3:41
  28. To effectively analyze the requirements for protection to rotavirus infection, a reliable animal model that reasonably mimics infection and disease in humans is needed. A requirement for an effective animal mo...

    Authors: Larry E Westerman, Baoming Jiang, Harold M McClure, Lauren J Snipes-Magaldi, Dixie D Griffin, Gary Shin, Jon R Gentsch and Roger I Glass
    Citation: Virology Journal 2006 3:40
  29. Many model systems of human viral disease involve human-mouse chimeric tissue. One such system is the recently developed SCID-beige/Alb-uPA mouse model of hepatitis C virus (HCV) infection which involves a hum...

    Authors: Kathie-Anne Walters, Michael A Joyce, Jill C Thompson, Sean Proll, James Wallace, Maria W Smith, Jeff Furlong, D Lorne Tyrrell and Michael G Katze
    Citation: Virology Journal 2006 3:37
  30. In recent years it was reported that the accumulation of point mutations in VP4 and VP7 genes of rotavirus strains was the main cause of the failure of the G or P-typing. Failures in the correct genotyping of G1,...

    Authors: Gabriel I Parra and Emilio E Espinola
    Citation: Virology Journal 2006 3:35
  31. The mature F protein of all known isolates of human respiratory syncytial virus (HRSV) contains fifteen absolutely conserved cysteine (C) residues that are highly conserved among the F proteins of other pneumo...

    Authors: Nicole D Day, Patrick J Branigan, Changbao Liu, Lester L Gutshall, Jianquan Luo, José A Melero, Robert T Sarisky and Alfred M Del Vecchio
    Citation: Virology Journal 2006 3:34
  32. Respiratory syncytial virus (RSV) infection is the major cause of bronchiolitis in infants and is a risk factor for the development of asthma. Allergic asthmatics are more susceptible to RSV infection and vira...

    Authors: Rajeswari Singam, Prasanna K Jena, Sumita Behera, Gary R Hellermann, Richard F Lockey, Dennis Ledford and Shyam S Mohapatra
    Citation: Virology Journal 2006 3:32
  33. Bacteriophages are an important repository of genetic diversity. As one of the major constituents of terrestrial biomass, they exert profound effects on the earth's ecology and microbial evolution by mediating...

    Authors: James M Nolan, Vasiliy Petrov, Claire Bertrand, Henry M Krisch and Jim D Karam
    Citation: Virology Journal 2006 3:30
  34. Adeno-associated virus type 2 (AAV-2) attachment and internalization is thought to be mediated by host cell membrane-associated heparan sulfate proteoglycans (HSPG). Lack of HSPG on the apical membrane of resp...

    Authors: Michael P Boyle, Raymond A Enke, Jeffrey B Reynolds, Peter J Mogayzel Jr, William B Guggino and Pamela L Zeitlin
    Citation: Virology Journal 2006 3:29
  35. Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DN...

    Authors: Larry A Hanson, Mary R Rudis, Marcia Vasquez-Lee and Roy D Montgomery
    Citation: Virology Journal 2006 3:28