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  1. Research

    Comparison of serological assays to titrate Hantaan and Seoul hantavirus-specific antibodies

    Hantaan and Seoul viruses, in the Hantavirus genus, are known to cause hemorrhagic fever with renal syndrome (HFRS). The plaque reduction neutralization test (PRNT), as conventional neutralization test for han...

    Weihong Li, Shouchun Cao, Quanfu Zhang, Jiandong Li, Shuo Zhang, Wei Wu, Jing Qu, Chuan Li, Mifang Liang and Dexin Li

    Virology Journal 2017 14:133

    Published on: 18 July 2017

  2. Research

    The effects of potato virus Y-derived virus small interfering RNAs of three biologically distinct strains on potato (Solanum tuberosum) transcriptome

    Potato virus Y (PVY) is one of the most economically important pathogen of potato that is present as biologically distinct strains. The virus-derived small interfering RNAs (vsiRNAs) f...

    Lindani Moyo, Shunmugiah V. Ramesh, Madhu Kappagantu, Neena Mitter, Vidyasagar Sathuvalli and Hanu R. Pappu

    Virology Journal 2017 14:129

    Published on: 17 July 2017

  3. Methodology

    Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus

    Goatpox virus (GTPV) and sheeppox virus (SPPV), which belong to the Capripoxvirus (CaPV), are economically important pathogens of small ruminants. Therefore, a sensitive, specific and rapid diagnostic assay for d...

    Yang Yang, Xiaodong Qin, Xiangle Zhang, Zhixun Zhao, Wei Zhang, Xueliang Zhu, Guozheng Cong, Yanmin Li and Zhidong Zhang

    Virology Journal 2017 14:131

    Published on: 17 July 2017

  4. Short report

    Prevalence of plasma autoantibody against cancer testis antigen NY-ESO-1 in HTLV-1 infected individuals with different clinical status

    Detection of specific immune responses against cancer/testis antigen NY-ESO-1 was recently reported in patients with adult T-cell leukemia/lymphoma (ATL) and human T-cell leukemia virus type 1 (HTLV-1)-infecte...

    Yasuo Shiohama, Tadasuke Naito, Toshio Matsuzaki, Reiko Tanaka, Takeaki Tomoyose, Hiroshi Takashima, Takuya Fukushima, Yuetsu Tanaka and Mineki Saito

    Virology Journal 2017 14:130

    Published on: 17 July 2017

  5. Research

    Semi-quantitative Influenza A population averages from a multiplex respiratory viral panel (RVP): potential for reflecting target sequence changes affecting the assay

    Yearly influenza virus mutations potentially affect the performance of molecular assays, if nucleic acid changes involve the sequences in the assay. Because individual patient viral loads depend on variables s...

    Kenneth H. Rand, Maura Pieretti, Rodney Arcenas, Stacy G. Beal, Herbert Houck, Emma Boslet and John A. Lednicky

    Virology Journal 2017 14:128

    Published on: 14 July 2017

  6. Research

    Interleukin-2 enhancer binding factor 2 interacts with the nsp9 or nsp2 of porcine reproductive and respiratory syndrome virus and exerts negatively regulatory effect on the viral replication

    Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failures in sows and respiratory diseases in growing pigs, resulting in huge economic loss for the pig production worldwide. The ...

    Xuexia Wen, Ting Bian, Zhibang Zhang, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Hanchun Yang and Kangzhen Yu

    Virology Journal 2017 14:125

    Published on: 11 July 2017

  7. Short Paper

    Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

    Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of...

    Mako Yanai, Madoka Sakai, Akiko Makino and Keizo Tomonaga

    Virology Journal 2017 14:126

    Published on: 11 July 2017

  8. Research

    Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

    Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group. Vaccination o...

    Joan E. M. van der Lubbe, Jessica Vreugdenhil, Sarra Damman, Joost Vaneman, Jaco Klap, Jaap Goudsmit, Katarina Radošević and Ramon Roozendaal

    Virology Journal 2017 14:123

    Published on: 26 June 2017

  9. Research

    6-methylmercaptopurine riboside, a thiopurine nucleoside with antiviral activity against canine distemper virus in vitro

    Canine distemper (CD) is a widespread infectious disease that can severely impact a variety of species in the order Carnivora, as well as non-carnivore species such as non-human primates. Despite large-scale v...

    Otávio Valério de Carvalho, Daniele Mendes Félix, Claudia de Camargo Tozato, Juliana Lopes Rangel Fietto, Márcia Rogéria de Almeida, Gustavo Costa Bressan, Lindomar José Pena and Abelardo Silva-Júnior

    Virology Journal 2017 14:124

    Published on: 26 June 2017

  10. Research

    Comparison of the protective efficacy between single and combination of recombinant adenoviruses expressing complete and truncated glycoprotein, and nucleoprotein of the pathogenic street rabies virus in mice

    Rabies is an important viral zoonosis that causes acute encephalitis and death in mammals. To date, several recombinant vaccines have been developed based on G protein, which is considered to be the main antig...

    Ha-Hyun Kim, Dong-Kun Yang, Jin-Ju Nah, Jae-Young Song and In-Soo Cho

    Virology Journal 2017 14:122

    Published on: 24 June 2017

  11. Short Report

    Chorioallantoic membranes of embryonated chicken eggs as an alternative system for isolation of equine influenza virus

    Influenza virus isolation in embryonated chicken eggs (ECEs) is not applicable for rapid diagnosis, however it allows the recovery and propagation of the viable virus. A low number of infectious virus particle...

    Ilona Marcelina Gora, Malgorzata Kwasnik, Jan Franciszek Zmudzinski and Wojciech Rozek

    Virology Journal 2017 14:120

    Published on: 21 June 2017

  12. Short Report

    Variability in P1 gene redefines phylogenetic relationships among cassava brown streak viruses

    Cassava brown streak disease is emerging as the most important viral disease of cassava in Africa, and is consequently a threat to food security. Two distinct species of the genus Ipomovirus (family Potyviridae) ...

    Willard Mbewe, Fred Tairo, Peter Sseruwagi, Joseph Ndunguru, Siobain Duffy, Ssetumba Mukasa, Ibrahim Benesi, Samar Sheat, Marianne Koerbler and Stephan Winter

    Virology Journal 2017 14:118

    Published on: 20 June 2017

  13. Research

    Epitope mapping and characterization of a novel Nsp10-specific monoclonal antibody that differentiates genotype 2 PRRSV from genotype 1 PRRSV

    Porcine reproductive and respiratory syndrome virus (PRRSV), the causative agent of PRRS, has two distinct and highly diverse genotypes (genotype 1 and genotype 2) in the field. Accurate diagnosis and differen...

    Zhibang Zhang, Xuexia Wen, Jianguo Dong, Xinna Ge, Lei Zhou, Hanchun Yang and Xin Guo

    Virology Journal 2017 14:116

    Published on: 19 June 2017

  14. Research

    Genome-wide analysis of codon usage bias in Bovine Coronavirus

    Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important econo...

    Matías Castells, Matías Victoria, Rodney Colina, Héctor Musto and Juan Cristina

    Virology Journal 2017 14:115

    Published on: 17 June 2017

  15. Research

    Cyclophilin B facilitates the replication of Orf virus

    Viruses interact with host cellular factors to construct a more favourable environment for their efficient replication. Expression of cyclophilin B (CypB), a cellular peptidyl-prolyl cis-trans isomerase (PPIase),...

    Kui Zhao, Jida Li, Wenqi He, Deguang Song, Ximu Zhang, Di Zhang, Yanlong Zhou and Feng Gao

    Virology Journal 2017 14:114

    Published on: 15 June 2017

  16. Short report

    Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array

    Our next generation sequencing (NGS)-based human papillomavirus (HPV) genotyping assay showed a high degree of concordance with the Roche Linear Array (LA) with as little as 1.25 ng formalin-fixed paraffin-emb...

    Rebecca G. Nowak, Nicholas P. Ambulos, Lisa M. Schumaker, Trevor J. Mathias, Ruth A. White, Jennifer Troyer, David Wells, Manhattan E. Charurat, Søren M. Bentzen and Kevin J. Cullen

    Virology Journal 2017 14:112

    Published on: 13 June 2017

  17. Research

    Molecular epidemiology of Avian Rotaviruses Group A and D shed by different bird species in Nigeria

    Avian rotaviruses (RVs) cause gastrointestinal diseases of birds worldwide. However, prevalence, diversity, epidemiology and phylogeny of RVs remain largely under-investigated in Africa.

    Maude Pauly, Oluwole O. Oni, Aurélie Sausy, Ademola A. Owoade, Christopher A. O. Adeyefa, Claude P. Muller, Judith M. Hübschen and Chantal J. Snoeck

    Virology Journal 2017 14:111

    Published on: 12 June 2017

  18. Research

    A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

    Avian coronavirus infectious bronchitis virus (IBV) is a respiratory pathogen of chickens that causes severe economic losses in the poultry industry worldwide. Major advances in the study of the molecular biol...

    Steven J. van Beurden, Alinda J. Berends, Annika Krämer-Kühl, Dieuwertje Spekreijse, Gilles Chénard, Hans-Christian Philipp, Egbert Mundt, Peter J. M. Rottier and M. Hélène Verheije

    Virology Journal 2017 14:109

    Published on: 12 June 2017

  19. Research

    Complete genome sequence of T’Ho virus, a novel putative flavivirus from the Yucatan Peninsula of Mexico

    We previously reported the discovery of a novel, putative flavivirus designated T’Ho virus in Culex quinquefasciatus mosquitoes in the Yucatan Peninsula of Mexico. A 1358-nt region of the NS5 gene was amplified a...

    Thomas Briese, Maria A. Loroño-Pino, Julian E. Garcia-Rejon, Jose A. Farfan-Ale, Carlos Machain-Williams, Karin S. Dorman, W. Ian Lipkin and Bradley J. Blitvich

    Virology Journal 2017 14:110

    Published on: 12 June 2017

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