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  1. Research

    Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice

    Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the out...

    Weiwei Gai, Xuexing Zheng, Chong Wang, Hualei Wang, Yongkun Zhao, Qi Wang, Gary Wong, Weijiao Zhang, Na Feng, Boning Qiu, Hang Chi, Nan Li, Tiecheng Wang, Yuwei Gao, Junjie Shan, Songtao Yang…

    Virology Journal 2017 14:204

    Published on: 25 October 2017

  2. Research

    Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants

    The pathogenesis of acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB) is not well understood. The aim of this study was to investigate whether there is an association between HBV polymerase (P...

    Shan Gao, Shivali S. Joshi, Carla Osiowy, Y. Chen, Carla S. Coffin and Z-P. Duan

    Virology Journal 2017 14:203

    Published on: 24 October 2017

  3. Research

    Genetic polymorphisms of HLA-DP and isolated anti-HBc are important subsets of occult hepatitis B infection in Indonesian blood donors: a case-control study

    Occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the serum and/or liver in HBsAg-negative individuals. OBI is associated with the risk of viral transmission, espe...

    Yan Mardian, Yoshihiko Yano, Widya Wasityastuti, Neneng Ratnasari, Yujiao Liang, Wahyu Aristyaning Putri, Teguh Triyono and Yoshitake Hayashi

    Virology Journal 2017 14:201

    Published on: 23 October 2017

  4. Research

    The proposed new species, cacao red vein virus, and three previously recognized badnavirus species are associated with cacao swollen shoot disease

    Cacao swollen shoot virus (CSSV), Cacao swollen shoot CD virus (CSSCDV), and Cacao swollen shoot Togo A virus (CSSTAV) cause cacao swollen shoot disease (CSSD) in West Africa. During 2...

    Nomatter Chingandu, Koffie Kouakou, Romain Aka, George Ameyaw, Osman A. Gutierrez, Hans-Werner Herrmann and Judith K. Brown

    Virology Journal 2017 14:199

    Published on: 19 October 2017

  5. Research

    Differential expression of porcine microRNAs in African swine fever virus infected pigs: a proof-of-concept study

    African swine fever (ASF) is a re-expanding devastating viral disease currently threatening the pig industry worldwide. MicroRNAs are a class of 17–25 nucleotide non- coding RNAs that have been shown to have c...

    Fernando Núñez-Hernández, Lester Josué Pérez, Marta Muñoz, Gonzalo Vera, Francesc Accensi, Armand Sánchez, Fernando Rodríguez and José I. Núñez

    Virology Journal 2017 14:198

    Published on: 17 October 2017

  6. Research

    Is MMTV associated with human breast cancer? Maybe, but probably not

    Conflicting results regarding the association of MMTV with human breast cancer have been reported. Published sequence data have indicated unique MMTV strains in some human samples. However, concerns regarding ...

    Raisa Perzova, Lynn Abbott, Patricia Benz, Steve Landas, Seema Khan, Jordan Glaser, Coleen K. Cunningham and Bernard Poiesz

    Virology Journal 2017 14:196

    Published on: 13 October 2017

  7. Short Report

    Detection and phylogenetic analyses of spike genes in porcine epidemic diarrhea virus strains circulating in China in 2016–2017

    Large-scale outbreaks of porcine epidemic diarrhea (PED) have re-emerged in China in recent years. However, little is known about the genetic diversity and molecular epidemiology of field strains of PED virus ...

    Qiaoling Zhang, Xinsheng Liu, Yuzhen Fang, Peng Zhou, Yonglu Wang and Yongguang Zhang

    Virology Journal 2017 14:194

    Published on: 10 October 2017

  8. Research

    A study of Epstein-Barr virus infection in the Chinese tree shrew(Tupaia belangeri chinensis)

    Epstein–Barr virus (EBV) is closely associated with many human diseases, including a variety of deadly human malignant tumours. However, due to the lack of ideal animal models,the biological characteristics of...

    Zhi Wang, Xiang Yi, Long Du, Hong Wang, Jie Tang, Menglin Wang, Chenglin Qi, Heng Li, Yongjing Lai, Wei Xia and Anzhou Tang

    Virology Journal 2017 14:193

    Published on: 6 October 2017

  9. Research

    Genetic analysis of porcine circovirus type 2 from pigs affected with PMWS in Chile reveals intergenotypic recombination

    Porcine circovirus type 2 (PCV2) is a very small, non-enveloped and icosahedral virus, with circular single stranded DNA genome. This virus is the most ubiquitous and persistent pathogen currently affecting th...

    Victor Neira, Natalia Ramos, Rodrigo Tapia, Juan Arbiza, Andrónico Neira-Carrillo, Manuel Quezada, Álvaro Ruiz and Sergio A. Bucarey

    Virology Journal 2017 14:191

    Published on: 4 October 2017

  10. Research

    Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro

    The aim of this study were to investigate the possible pro-apoptotic mechanisms of the recombinant Newcastle disease virus (NDV) strain rL-RVG, which expresses the rabies virus glycoprotein, in A549 lung adeno...

    Yulan Yan, Chunxiang Su, Min Hang, Hua Huang, Yinghai Zhao, Xiaomei Shao and Xuefeng Bu

    Virology Journal 2017 14:190

    Published on: 3 October 2017

  11. Research

    Viral metagenomics of aphids present in bean and maize plots on mixed-use farms in Kenya reveals the presence of three dicistroviruses including a novel Big Sioux River virus-like dicistrovirus

    Aphids are major vectors of plant viruses. Common bean (Phaseolus vulgaris L.) and maize (Zea mays L.) are important crops that are vulnerable to aphid herbivory and aphid-transmitted viruses. In East and Central...

    Francis O. Wamonje, George N. Michuki, Luke A. Braidwood, Joyce N. Njuguna, J. Musembi Mutuku, Appolinaire Djikeng, Jagger J. W. Harvey and John P. Carr

    Virology Journal 2017 14:188

    Published on: 2 October 2017

  12. Research

    Phylogenetic, antigenic and biological characterization of pigeon paramyxovirus type 1 circulating in China

    For many years, ND has been one of the most important infectious pigeon diseases in China. In recent years, a high mortality has been observed in ND-infected pigeons in China. Mortality is from 40% to 80% or 1...

    Xusheng Qiu, Chunchun Meng, Yuan Zhan, Shengqing Yu, Shichao Li, Tingting Ren, Weifeng Yuan, Shuqin Xu, Yingjie Sun, Lei Tan, Cuiping Song, Ying Liao, Zhuang Ding, Xiufan Liu and Chan Ding

    Virology Journal 2017 14:186

    Published on: 29 September 2017

  13. Research

    Identification of a novel linear B-cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

    The Nucleoprotein (NP) is the most abundant and highly immunogenic protein in canine distemper virus (CDV), playing an important role in CDV viral replication and assembly.

    Li Yi, Zhigang Cao, Mingwei Tong, Yuening Cheng, Yong Yang, Shuang Li, Jianke Wang, Peng Lin, Yaru Sun, Miao Zhang and Shipeng Cheng

    Virology Journal 2017 14:187

    Published on: 29 September 2017

  14. Short Report

    Two mutations in the HR2 region of Newcastle disease virus fusion protein with a cleavage motif “RRQRRL” are critical for fusogenic activity

    Newcastle disease virus (NDV) causes severe diseases in avian species. Its fusion protein cleavage site (Fcs) is a major contributor to virulence and membrane fusion. Previous studies showed that a change from...

    Yanhong Wang, Youkun Bi, Wanqi Yu, Ning Wei, Wenbin Wang, Qiaolin Wei, Xinglong Wang, Shuxia Zhang, Zengqi Yang and Sa Xiao

    Virology Journal 2017 14:185

    Published on: 25 September 2017

  15. Research

    Molecular characterization of the duck enteritis virus US10 protein

    There is little information regarding the duck enteritis virus (DEV) US10 gene and its molecular characterization.

    Daixi Zhang, Maoyin Lai, Anchun Cheng, Mingshu Wang, Ying Wu, Qiao Yang, Mafeng Liu, Dekang Zhu, Renyong Jia, Shun Chen, Kunfeng Sun, Xinxin Zhao and Xiaoyue Chen

    Virology Journal 2017 14:183

    Published on: 20 September 2017

  16. Research

    A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro

    Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step...

    Sabrina Weiss, Piotr Wojtek Dabrowski, Andreas Kurth, Siv Aina J. Leendertz and Fabian H. Leendertz

    Virology Journal 2017 14:181

    Published on: 18 September 2017

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