Garcia-Sastre A, Biron CA: Type 1 interferons and the virus-host relationship: a lesson in detente. Science 2006, 312: 879-882. 10.1126/science.1125676
Article
PubMed
CAS
Google Scholar
Newby CM, Sabin L, Pekosz A: The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cells. J Virol 2007, 81: 9469-9480. 10.1128/JVI.00989-07
Article
PubMed
CAS
PubMed Central
Google Scholar
Fernandez-Sesm A: The influenza virus NS1 protein: inhibitor of innate and adaptive immunity. Infect Disord Drug Targets 2007, 7: 336-343. 10.2174/187152607783018754
Article
Google Scholar
Hale GH, Randall RE, Ortìn J, Jackson D: The multifunctional NS1 protein of influenza A viruses. J Gen Virol 2008, 89: 2359-2376. 10.1099/vir.0.2008/004606-0
Article
PubMed
CAS
Google Scholar
Melen K, Kinnunen L, Fagerlund R, Ikonen N, Twu KY, Krug RM, Iulkunen I: Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes. J Virol 2007, 81: 5995-6006. 10.1128/JVI.01714-06
Article
PubMed
CAS
PubMed Central
Google Scholar
Obenauer JC, Denson J, Mehta PK, Su X, Mukatira S, Finkelstein DB, Xu X, Wang J, Fan Y, Rakestraw KM, Webster RG, Hoffmann E, Krauss S, Zheng J, Zhang Z, Naeve CV: Large-scale sequence analysis of avian influenza isolates. Science 2006, 311: 1576-1580. 10.1126/science.1121586
Article
PubMed
CAS
Google Scholar
Palese P, Shaw ML: Orthomyxoviridae : the viruses and their replication. In Fields Virology. 5th edition. Edited by: Knipe DM, Howley. Philadelphia: Lippincott Williams & Wilkins; 2007:1647-1689.
Google Scholar
Smith GJD, Vijaykrishna D, Bahl J, Lycett SJ, Worobey M, Pybus OG, Ma SK, Cheung CM, Raghwani J, Bhatt S, Peiris JSM, Guan Y, Rambaut A: Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A pandemic. Nature 2009, 459: 1122-1125. 10.1038/nature08182
Article
PubMed
CAS
Google Scholar
Centers for Disease Control and Prevention: Update: isolation of avian influenza A (H5N1) viruses from humans-Hong Kong, 1997-1998. JAMA 1998, 279: 347-348. 10.1001/jama.279.5.347
Article
Google Scholar
World Health Organization: Cumulative number of confirmed human cases of avian influenza A/(H5N1) reported to WHO. 2008.
Google Scholar
Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Tauben-berger JK, Bumgarner RE, Palese P, Katze MG, Garcia-Sastre A: Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc Natl Acad Sci USA 2002, 99: 10736-10741. 10.1073/pnas.112338099
Article
PubMed
CAS
PubMed Central
Google Scholar
Seo SH, Hoffmann E, Webster RG: Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med 2002, 8: 950-954. 10.1038/nm757
Article
PubMed
CAS
Google Scholar
Seo SH, Hoffmann E, Webster RG: The NS1 of H5N1 influenza viruses circumvents the host anti-viral cytokine responses. Virus Res 2004, 103: 107-113. 10.1016/j.virusres.2004.02.022
Article
PubMed
CAS
Google Scholar
Treanor JJ, Snyder MH, London WT, Murphy BR: The B allele of the NS gene of avian influenza viruses, but not the A allele, attenuates a human influenza A virus for squirrel monkeys. Virology 1989, 171: 1-9. 10.1016/0042-6822(89)90504-7
Article
PubMed
CAS
Google Scholar
Ludwig S, Shultz U, Mandler J, Fitch WM, Scholtissek C: Phylogenetic relationship of the nonstructural (NS) genes of the influenza A viruses. Virology 1991, 183: 566-577. 10.1016/0042-6822(91)90985-K
Article
PubMed
CAS
Google Scholar
Zohari S, Gyarmati P, Thoren P, Czifra G, Brojer C, Belak S, Berg M: Genetic characterization of the NS gene indicates cocirculation of two sub-lineages of highly pathogenic avian influenza virus of H5N1 subtype in Northern Europe in 2006. Virus Genes 2008, 36: 117-125. 10.1007/s11262-007-0188-7
Article
PubMed
CAS
Google Scholar
Rovida F, Percivalle E, Zavattoni M, Torsellini M, Sarasini A, Campanini G, Paolucci S, Baldanti F, Revello MG, Gerna G: Monoclonal antibodies versus reverse-transcription-PCR for detection of respiratory viruses in a patient population with respiratory tract infections admitted to hospital. J Med Virol 2005, 75: 336-347. 10.1002/jmv.20276
Article
PubMed
CAS
Google Scholar
Sarasini A, Percivalle E, Rovida F, Campanini G, Genini E, Torsellini M, Paolucci S, Baldanti F, Marchi A, Revello MG, Gerna G: Detection and pathogenicity of human metapneumovirus respiratory infections in pediatric Italian patients during a winter-spring season. J Clin Virol 2006, 35: 59-68. 10.1016/j.jcv.2005.05.010
Article
PubMed
Google Scholar
Percivalle E, Rovida F, Piralla A, Rognoni V, Zavattoni M, Baldanti F, Marchi A, Gerna G: Rapid typing, subtyping and RNA quantification of influenza virus type A strains in respiratory secretions. New Microbiologica 2008, 31: 319-327.
PubMed
CAS
Google Scholar
Tamura K, Dudley J, Nei M, Kumar S: MEGA 4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 2007, 24: 1596-1599. 10.1093/molbev/msm092
Article
PubMed
CAS
Google Scholar
Rambaut A, Pybus OG, Nelson MI, Viboud C, Tauenberger JK, Holmes EC: The genomic and epidemiological dynamics of human influenza A virus. Nature 2008, 453: 615-620. 10.1038/nature06945
Article
PubMed
CAS
PubMed Central
Google Scholar
Greenbaum JA, Kotturi MF, Kim Y, Oseroff C, Vaughan K, Salimi N, Vita R, Ponomarenco J, Scheuermann RH, Sette A, Peters B: Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population. Proc Natl Acad Sci USA 2009, 106: 20365-20370. 10.1073/pnas.0911580106
Article
PubMed
CAS
PubMed Central
Google Scholar
Suarez DL, Perdue ML: Multiple alignment comparison of the non-structural genes of influenza A viruses. Virus Res 1998, 54: 59-69. 10.1016/S0168-1702(98)00011-2
Article
PubMed
CAS
Google Scholar
Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb RA: A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proc Natl Acad Sci USA 2008, 105: 4381-4386. 10.1073/pnas.0800482105
Article
PubMed
CAS
PubMed Central
Google Scholar
Dundon WG, Milani A, Cattoli G, Capua I: Progressive truncation of the Non-Structural 1 gene of H7N1 avian influenza viruses following extensive circulation in poultry. Virus Res 2006, 119: 171-176. 10.1016/j.virusres.2006.01.005
Article
PubMed
CAS
Google Scholar
Min JY, Li S, Sen GC, Krug RM: A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology 2007, 363: 236-243. 10.1016/j.virol.2007.01.038
Article
PubMed
CAS
Google Scholar