Hepatitis viruses

Section edited by Alan McLachlan

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  1. Research

    Antiviral efficacy of entecavir for hepatitis B virus rtA181V/T mutants

    The amino acid substitution at position 181 of the Hepatitis B virus (HBV) polymerase is a multi-drug resistance affecting both the L-nucleoside and acyclic phosphonate nucleotide groups. Data is limited on th...

    Ping Li, Jiabao Geng, Wei Li, Xiaobing Xu, Xin Zhang, Wenkai Zheng, Yuecheng Yu, Zhiguo Yang and Maorong Wang

    Virology Journal 2017 14:68

    Published on: 4 April 2017

  2. Methodology

    Analytical characteristics and comparative evaluation of Aptima HCV quant Dx assay with the Abbott RealTime HCV assay and Roche COBAS AmpliPrep/COBAS TaqMan HCV quantitative test v2.0

    The Aptima HCV Quant Dx assay (Aptima assay) is a fully automated quantitative assay on the Panther® system. This assay is intended for confirmation of diagnosis and monitoring of HCV RNA in plasma and serum s...

    A. Worlock, D. Blair, M. Hunsicker, T. Le-Nguyen, C. Motta, C. Nguyen, E. Papachristou, J. Pham, A. Williams, M. Vi, B. Vinluan and A. Hatzakis

    Virology Journal 2017 14:66

    Published on: 4 April 2017

  3. Research

    SVR Rates of HCV-infected population under PEG-IFN-α/R treatment in Northwest China

    Chronic HCV Patients taking PEG-IFN-α/R from different ethnic groups have different probabilities of reaching a sustained viral response (SVR). There are many influence factors, such as HCV genotype, IL-28B si...

    Yanhua Li, Jiuping Wang, Juan Wang, Yunfeng Xiao, Bin Xu, Hongwei Li, Liu Yang, Xiaoke Hao and Yueyun Ma

    Virology Journal 2017 14:62

    Published on: 23 March 2017

  4. Research

    Effect of 48-week pegylated interferon α-2a or nucleos(t)ide analogue therapy on renal function in Chinese patients with chronic hepatitis B

    Controversy remains as to whether antiviral agents contribute to renal dysfunction in patients with chronic hepatitis B virus (HBV) infection. Thus, the aim of study was to analyze the changes in renal functio...

    Ye Zhang, Wei-Lu Zhang, Xiao-Wen Pang, Lin-Xu Wang, Xin Wei, Chang-Xing Huang, Xue-Fan Bai, Shuai Han, Lin-Na Liu and Jian-Qi Lian

    Virology Journal 2017 14:49

    Published on: 9 March 2017

  5. Research

    Community seroprevalence of hepatitis B, C and human immunodeficiency virus in adult population in gojjam zones, northwest Ethiopia

    In Ethiopia, there is lack of data on the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immune deficiency virus (HIV) infections in adult population at community level. This study ai...

    Bayeh Abera, Yesuf Adem, Mulat Yimer, Wondemagegn Mulu, Yohannes Zenebe and Zewdie Mekonnen

    Virology Journal 2017 14:21

    Published on: 6 February 2017

  6. Research

    HBsAg and HBeAg in the prediction of a clinical response to peginterferon α-2b therapy in Chinese HBeAg-positive patients

    This study aimed to evaluate the predictive values of hepatitis B e antigen (HBeAg) and hepatitis B surface antigen (HBsAg) levels in 171 Chinese patients with chronic hepatitis B who received a 48-week course...

    Song Yang, Huichun Xing, Yuming Wang, Jinlin Hou, Duande Luo, Qing Xie, Qin Ning, Hong Ren, Huiguo Ding, Jifang Sheng, Lai Wei, Shijun Chen, Xiaoling Fan, Wenxiang Huang, Chen Pan, Zhiliang Gao…

    Virology Journal 2016 13:180

    Published on: 28 October 2016

  7. Research

    Serologic and genotypic characterization of hepatitis B virus in HIV-1 infected patients from South West and Littoral Regions of Cameroon

    HBV and HIV share similar transmission routes. Concurrent infection with the two viruses usually results in more severe and progressive liver disease, and a higher incidence of cirrhosis, liver cancer and mort...

    Tshifhiwa Magoro, George Gachara, Lufuno Mavhandu, Emmaculate Lum, Helen K. Kimbi, Roland N. Ndip and Pascal Bessong

    Virology Journal 2016 13:178

    Published on: 21 October 2016

  8. Research

    Characterization of differential antibody production against hepatitis C virus in different HCV infection status

    The Centers for Disease Control and Prevention (CDC) issued an update on hepatitis C virus (HCV) testing approach, in which it omitted the use of recombinant immunoblot assay (RIBA) in the diagnostic algorithm...

    Mona Rafik, Salwa Bakr, Dina Soliman, Nesrine Mohammed, Dina Ragab, Walid Abd ElHady and Nancy Samir

    Virology Journal 2016 13:116

    Published on: 30 June 2016

  9. Research

    Changing etiologies and outcome of liver failure in Southwest China

    The prognosis of liver failure depends greatly on the underlying cause, and there were few data about the prognosis, etiologies or trigger factors of liver failure in China based on long-term and large samples...

    Gui-Juan Xie, Hui-Yan Zhang, Qing Chen, Hui-Min Liu, Jian-Ping You, Sha Yang, Qing Mao and Xu-Qing Zhang

    Virology Journal 2016 13:89

    Published on: 4 June 2016

  10. Research

    Occult Hepatitis B virus infection in previously screened, blood donors in Ile-Ife, Nigeria: implications for blood transfusion and stem cell transplantation

    Hepatitis B virus (HBV) transmission through blood transfusion is reduced by screening for hepatitis B surface antigen (HBsAg). However this method cannot detect the presence of occult hepatitis B virus infect...

    Amadin A. Olotu, Adesola O. Oyelese, Lateef Salawu, Rosemary A. Audu, Azuka P. Okwuraiwe and Aaron O. Aboderin

    Virology Journal 2016 13:76

    Published on: 5 May 2016

  11. Research

    Increased CD56bright NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype

    HIV-HCV co-infection is associated with accelerated progression to hepatic fibrosis, cirrhosis and hepatocellular carcinoma than HCV mono-infection. The contribution of innate immunity during HIV-HCV co-infect...

    Suvercha Bhardwaj, Fareed Ahmad, Heiner Wedemeyer, Marcus Cornberg, Julian Schulze zur Wiesch, Jan van Lunzen, Shiv K. Sarin, Reinhold E. Schmidt and Dirk Meyer-Olson

    Virology Journal 2016 13:67

    Published on: 18 April 2016

  12. Research

    Molecular epidemiology of hepatitis D virus circulating in Southwestern Nigeria

    Hepatitis B virus (HBV) and hepatitis D virus (HDV) infections are major public health problems in sub-Saharan Africa. Whereas it is known that HBV infection is endemic in Nigeria, there is only little data ab...

    Oluyinka Oladele Opaleye, Oluwatoyin Margaret Japhet, Olubusuyi Moses Adewumi, Ewean Chukwuma Omoruyi, Olusola Anuoluwapo Akanbi, Adeolu Sunday Oluremi, Bo Wang, Hoang van Tong, Thirumalaisamy P. Velavan and C.-Thomas Bock

    Virology Journal 2016 13:61

    Published on: 5 April 2016

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