Negative-strand RNA viruses

Section edited by Andrew Easton

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  1. Methodology

    A robust and cost-effective approach to sequence and analyze complete genomes of small RNA viruses

    Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic acids. The use of sequence-independent amplification of viral nucleic acids without utilization of target-specific primers provides adva...

    Kiril M. Dimitrov, Poonam Sharma, Jeremy D. Volkening, Iryna V. Goraichuk, Abdul Wajid, Shafqat Fatima Rehmani, Asma Basharat, Ismaila Shittu, Tony M. Joannis, Patti J. Miller and Claudio L. Afonso

    Virology Journal 2017 14:72

    Published on: 7 April 2017

  2. Methodology

    Development of real-time and lateral flow strip reverse transcription recombinase polymerase Amplification assays for rapid detection of peste des petits ruminants virus

    Peste des petits ruminants (PPR) is an economically important, Office International des Epizooties (OIE) notifiable, transboundary viral disease of small ruminants such as sheep and goat. PPR virus (PPRV), a n...

    Yang Yang, Xiaodong Qin, Yiming Song, Wei Zhang, Gaowei Hu, Yongxi Dou, Yanmin Li and Zhidong Zhang

    Virology Journal 2017 14:24

    Published on: 7 February 2017

  3. Research

    A DNA vaccine encoding the viral hemorrhagic septicemia virus genotype IVb glycoprotein confers protection in muskellunge (Esox masquinongy), rainbow trout (Oncorhynchus mykiss), brown trout (Salmo trutta), and lake trout (Salvelinus namaycush)

    The viral hemorrhagic septicemia virus (VHSV) is one of the most serious fish pathogens. In 2003, a novel sublineage (genotype IVb) of this deadly virus emerged in the Great Lakes basin causing serious fish ki...

    Isaac F. Standish, Elena V. Millard, Travis O. Brenden and Mohamed Faisal

    Virology Journal 2016 13:203

    Published on: 2 December 2016

  4. Review

    Host cytoskeleton in respiratory syncytial virus assembly and budding

    Respiratory syncytial virus (RSV) is one of the major pathogens responsible for lower respiratory tract infections (LRTI) in young children, the elderly, and the immunosuppressed. Currently, there are no antiv...

    Shadi Shahriari, James Gordon and Reena Ghildyal

    Virology Journal 2016 13:161

    Published on: 26 September 2016

  5. Research

    Common position of indels that cause deviations from canonical genome organization in different measles virus strains

    The canonical genome organization of measles virus (MV) is characterized by total size of 15 894 nucleotides (nts) and defined length of every genomic region, both coding and non-coding. Only rarely have repor...

    Jelena Ivancic-Jelecki, Anamarija Slovic, Maja Šantak, Goran Tešović and Dubravko Forcic

    Virology Journal 2016 13:134

    Published on: 29 July 2016

  6. Short report

    Differences in viral load among human respiratory syncytial virus genotypes in hospitalized children with severe acute respiratory infections in the Philippines

    Human respiratory syncytial virus (HRSV) is a leading viral etiologic agent of pediatric lower respiratory infections, including bronchiolitis and pneumonia. Two antigenic subgroups, HRSV-A and B, each contain...

    Francois Marie Ngako Kadji, Michiko Okamoto, Yuki Furuse, Raita Tamaki, Akira Suzuki, Irene Lirio, Clyde Dapat, Rungnapa Malasao, Mariko Saito, Gay Anne Granada Pedrera-Rico, Veronica Tallo, Socorro Lupisan, Mayuko Saito and Hitoshi Oshitani

    Virology Journal 2016 13:113

    Published on: 27 June 2016

  7. Research

    Development of real-time reverse transcriptase qPCR assays for the detection of Punta Toro virus and Pichinde virus

    Research with high biocontainment pathogens such as Rift Valley fever virus (RVFV) and Lassa virus (LASV) is expensive, potentially hazardous, and limited to select institutions. Surrogate pathogens such as Pu...

    Christopher P. Stefan, Kitty Chase, Susan Coyne, David A. Kulesh, Timothy D. Minogue and Jeffrey W. Koehler

    Virology Journal 2016 13:54

    Published on: 31 March 2016

  8. Research

    Actin- and clathrin-dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus

    Respiratory syncytial virus (RSV) can cause recurrent and severe respiratory tract infections. Cytoskeletal proteins are often involved during viral infections, either for cell entry or the initiation of the i...

    Jop Jans, Hicham elMoussaoui, Ronald de Groot, Marien I. de Jonge and Gerben Ferwerda

    Virology Journal 2016 13:52

    Published on: 22 March 2016

  9. Research

    Protective efficacy of a recombinant Newcastle disease virus expressing glycoprotein of vesicular stomatitis virus in mice

    Vesicular stomatitis virus (VSV) causes severe losses to the animal husbandry industry. In this study, a recombinant Newcastle disease virus (NDV) expressing the glycoprotein (G) of VSV (rL-VSV-G) was construc...

    Minmin Zhang, Jinying Ge, Xiaofang Li, Weiye Chen, Xijun Wang, Zhiyuan Wen and Zhigao Bu

    Virology Journal 2016 13:31

    Published on: 24 February 2016

  10. Short report

    Fugong virus, a novel hantavirus harbored by the small oriental vole (Eothenomys eleusis) in China

    Rodents are natural reservoirs of hantaviruses, which cause two disease types: hemorrhagic fever with renal syndrome in Eurasia and hantavirus pulmonary syndrome in North America. Hantaviruses related human ca...

    Xing-Yi Ge, Wei-Hong Yang, Hong Pan, Ji-Hua Zhou, Xi Han, Guang-Jian Zhu, James S. Desmond, Peter Daszak, Zheng-Li Shi and Yun-Zhi Zhang

    Virology Journal 2016 13:27

    Published on: 16 February 2016

    The Erratum to this article has been published in Virology Journal 2016 13:75

  11. Research

    Identification of mumps virus protein and lipid composition by mass spectrometry

    Mumps virus is a negative-sense, single stranded RNA virus consisting of a ribonucleocapsid core enveloped by a lipid membrane derived from host cell, which causes mumps disease preventable by vaccination. Sin...

    Marija Brgles, Maximilian Bonta, Maja Šantak, Maja Jagušić, Dubravko Forčić, Beata Halassy, Günter Allmaier and Martina Marchetti-Deschmann

    Virology Journal 2016 13:9

    Published on: 14 January 2016

  12. Research

    The M, F and HN genes of genotype VIId Newcastle disease virus are associated with the severe pathological changes in the spleen of chickens

    The strains of the genotype VIId Newcastle disease virus (NDV) induce more severe tissue damage in lymphoid organs than other virulent strains. The underlying molecular mechanisms are poorly understood.

    Yan Kai, Zenglei Hu, Haixu Xu, Shunlin Hu, Jie Zhu, Jiao Hu, Xiaoquan Wang, Xiaowen Liu and Xiufan Liu

    Virology Journal 2015 12:133

    Published on: 4 September 2015

  13. Research

    Surveillance of avirulent Newcastle disease viruses at live bird markets in Eastern China during 2008–2012 reveals a new sub-genotype of class I virus

    The strains of Newcastle disease virus (NDV) can be divided into two distinct clades: class I and class II. At present, limited molecular epidemiological data are available for the class I virus at live bird m...

    Jie Zhu, Haixu Xu, Jingjing Liu, Zhenzhen Zhao, Shunlin Hu, Xiaoquan Wang and Xiufan Liu

    Virology Journal 2014 11:211

    Published on: 4 December 2014

  14. Short report

    Identification of rhabdoviral sequences in oropharyngeal swabs from German and Danish bats

    In the frame of active lyssavirus surveillance in bats, oropharyngeal swabs from German (N = 2297) and Danish (N = 134) insectivorous bats were investigated using a newly developed generic pan-lyssavirus real-...

    Melina Fischer, Conrad M Freuling, Thomas Müller, Juliane Schatz, Thomas Bruun Rasmussen, Mariann Chriel, Anne Balkema-Buschmann, Martin Beer and Bernd Hoffmann

    Virology Journal 2014 11:196

    Published on: 25 November 2014

  15. Research

    Characterization of a new genotype of avian bornavirus from wild ducks

    Avian bornaviruses (ABV) are a recently described group of intranuclear negative-stranded RNA viruses (Order Mononegavirales, Family Bornaviridae). At least 13 different ABV genotypes have been described. One gen...

    Jianhua Guo, H L Shivaprasad, Raquel R Rech, Jill J Heatley, Ian Tizard and Susan Payne

    Virology Journal 2014 11:197

    Published on: 19 November 2014

  16. Research

    Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein

    There are no approved small molecule drug therapies for human respiratory syncytial virus (hRSV), a cause of morbidity and mortality in at-risk newborns, the immunocompromised, and the elderly. We have investi...

    Adam B Shapiro, Ning Gao, Nichole O’Connell, Jun Hu, Jason Thresher, Rong-Fang Gu, Ross Overman, Ian M Hardern and Graham G Sproat

    Virology Journal 2014 11:191

    Published on: 19 November 2014

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