Skip to main content

Articles

Page 66 of 76

  1. The UL97 kinase has been shown to phosphorylate and inactivate the retinoblastoma protein (Rb) and has three consensus Rb-binding motifs that might contribute to this activity. Recombinant viruses containing m...

    Authors: Rachel B Gill, Samuel L Frederick, Caroll B Hartline, Sunwen Chou and Mark N Prichard

    Citation: Virology Journal 2009 6:9

    Content type: Short report

    Published on:

  2. Various members of the mint family have been used historically in Chinese and Native American medicine. Many of these same family members, including Prunella vulgaris, have been reported to have anti-viral activi...

    Authors: Melinda A Brindley, Mark P Widrlechner, Joe-Ann McCoy, Patricia Murphy, Cathy Hauck, Ludmila Rizshsky, Basil Nikolau and Wendy Maury

    Citation: Virology Journal 2009 6:8

    Content type: Research

    Published on:

  3. Sci-B-Vac™ is a recombinant, hepatitis B vaccine derived from a mammalian cell line and containing hepatitis B surface antigen (HBsAg) as well as preS1 and preS2 antigens. Few studies have been performed on th...

    Authors: Ulla B Hellström, Kazimierz Madalinski and Staffan PE Sylvan

    Citation: Virology Journal 2009 6:7

    Content type: Research

    Published on:

  4. Affecting both livestock and humans, Rift Valley Fever is considered as one of the most important viral zoonoses in Africa. However, no licensed vaccines or effective treatments are yet available for human use...

    Authors: Nina Lagerqvist, Jonas Näslund, Åke Lundkvist, Michèle Bouloy, Clas Ahlm and Göran Bucht

    Citation: Virology Journal 2009 6:6

    Content type: Research

    Published on:

  5. Viral infections are frequently cited as a major environmental factor involved in subacute thyroiditis and autoimmune thyroid diseases This review examines the data related to the role of viruses in the develo...

    Authors: Rachel Desailloud and Didier Hober

    Citation: Virology Journal 2009 6:5

    Content type: Review

    Published on:

  6. No one likes to feel like they have been manipulated, but in the case of cytomegalovirus (CMV) immune manipulation, we do not really have much choice. Whether you call it CMV immune modulation, manipulation, o...

    Authors: Mindy Miller-Kittrell and Tim E Sparer

    Citation: Virology Journal 2009 6:4

    Content type: Review

    Published on:

  7. Adeno-associated virus (AAV) vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product...

    Authors: Shuiliang Shi, Scott A Mercer, Robert Dilley and Stephen B Trippel

    Citation: Virology Journal 2009 6:3

    Content type: Research

    Published on:

  8. Even though two prophylactic vaccines against HPV are currently licensed, infections by the virus continue to be a major health problem mainly in developing countries. The cost of the vaccines limits wide-scal...

    Authors: Georgina Paz de la Rosa, Alberto Monroy-García, María de Lourdes Mora-García, Cristina Gehibie Reynaga Peña, Jorge Hernández-Montes, Benny Weiss-Steider and Miguel Angel Gómez Lim

    Citation: Virology Journal 2009 6:2

    Content type: Research

    Published on:

  9. Dengue virus type 1 (DENV-1) have been mostly circulating silently with dominant serotypes DENV-2 and DENV-3 in India. However recent times have marked an increase in DENV-1 circulation in yearly outbreaks. Ma...

    Authors: Himani Kukreti, Paban Kumar Dash, Manmohan Parida, Artee Chaudhary, Parag Saxena, RS Rautela, Veena Mittal, Mala Chhabra, D Bhattacharya, Shiv Lal, PV Lakshmana Rao and Arvind Rai

    Citation: Virology Journal 2009 6:1

    Content type: Research

    Published on:

  10. The evolutionary success of La Crosse virus (LACV, family Bunyaviridae) is due to its ability to adapt to changing conditions through intramolecular genetic changes and segment reassortment. Vertical transmission...

    Authors: Sara M Reese, Bradley J Blitvich, Carol D Blair, Dave Geske, Barry J Beaty and William C Black IV

    Citation: Virology Journal 2008 5:164

    Content type: Research

    Published on:

  11. Cell entry and cell-to-cell spread of the highly pathogenic Nipah virus (NiV) requires binding of the NiV G protein to cellular ephrin receptors and subsequent NiV F-mediated fusion. Since expression levels of...

    Authors: Lena Thiel, Sandra Diederich, Stephanie Erbar, Dennis Pfaff, Hellmut G Augustin and Andrea Maisner

    Citation: Virology Journal 2008 5:163

    Content type: Research

    Published on:

  12. DSB, the 3-O-(3',3'dimethylsuccinyl) derivative of betulinic acid, blocks the last step of protease-mediated processing of HIV-1 Gag precursor (Pr55Gag), which leads to immature, noninfectious virions. When admin...

    Authors: Sandrina DaFonseca, Pascale Coric, Bernard Gay, Saw See Hong, Serge Bouaziz and Pierre Boulanger

    Citation: Virology Journal 2008 5:162

    Content type: Research

    Published on:

  13. Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral vectors expressing the ...

    Authors: Megan M Illick, Luis M Branco, Joseph N Fair, Kerry A Illick, Alex Matschiner, Randal Schoepp, Robert F Garry and Mary C Guttieri

    Citation: Virology Journal 2008 5:161

    Content type: Research

    Published on:

  14. Positive selection pressure acting on protein-coding sequences is usually inferred when the rate of nonsynonymous substitution is greater than the synonymous rate. However, purifying selection acting directly ...

    Authors: Nobubelo K Ngandu, Konrad Scheffler, Penny Moore, Zenda Woodman, Darren Martin and Cathal Seoighe

    Citation: Virology Journal 2008 5:160

    Content type: Research

    Published on:

  15. Diarrhea, the third leading infectious cause of death worldwide, causes approximately 2 million deaths a year. Approximately 40% of these cases are of unknown etiology. We previously developed a metagenomic st...

    Authors: Lori R Holtz, Stacy R Finkbeiner, Carl D Kirkwood and David Wang

    Citation: Virology Journal 2008 5:159

    Content type: Short report

    Published on:

  16. Hepatitis E virus (HEV) is highly endemic in several African countries with high mortality rate among pregnant women. Nothing is known about the circulation of this virus in central Africa. We evaluated theref...

    Authors: Mélanie Caron and Mirdad Kazanji

    Citation: Virology Journal 2008 5:158

    Content type: Short report

    Published on:

  17. An infectious bronchitis virus Arkansas DPI (Ark DPI) virulent strain was sequenced, analyzed and compared with many different IBV strains and coronaviruses. The genome of Ark DPI consists of 27,620 nucleotide...

    Authors: Arun Ammayappan, Chitra Upadhyay, Jack Gelb Jr and Vikram N Vakharia

    Citation: Virology Journal 2008 5:157

    Content type: Short report

    Published on:

  18. Hepatitis A virus (HAV), the causative agent of acute hepatitis in humans, is an atypical Picornaviridae that grows poorly in cell culture. HAV titrations are laborious and time-consuming because the virus in ...

    Authors: Krishnamurthy Konduru, Maria Luisa Virata-Theimer, Mei-ying W Yu and Gerardo G Kaplan

    Citation: Virology Journal 2008 5:155

    Content type: Methodology

    Published on:

  19. In immunopathological diseases, such as multiple sclerosis (MS), genetic and environmental factors that contribute to the initiation and progression of the disease are often discussed. The Theiler murine encep...

    Authors: Nicolas P Turrin

    Citation: Virology Journal 2008 5:154

    Content type: Research

    Published on:

  20. To perform a retrospective analysis of patients with IgM antibodies to dengue fever infection to determine the serotypes present by molecular techniques. A representative sample (~20%/per year) of patients dia...

    Authors: M Gittens-St Hilaire and Nicole Clarke-Greenidge

    Citation: Virology Journal 2008 5:152

    Content type: Research

    Published on:

  21. PVs (PV) are small, non-enveloped, double-stranded DNA viruses that have been identified as the primary etiological agent for cervical cancer and their potential for malignant transformation in mucosal tissue ...

    Authors: John Lowe, Debasis Panda, Suzanne Rose, Ty Jensen, Willie A Hughes, For Yue Tso and Peter C Angeletti

    Citation: Virology Journal 2008 5:150

    Content type: Research

    Published on:

  22. The I5L gene is one of ~90 genes that are conserved throughout the chordopoxvirus family, and hence are presumed to play vital roles in the poxvirus life cycle. Previous work had indicated that the VP13 protei...

    Authors: Bethany Unger, R Jeremy Nichols, Eleni S Stanitsa and Paula Traktman

    Citation: Virology Journal 2008 5:148

    Content type: Research

    Published on:

  23. Although the important role of the non-structural 1 (NS) gene of influenza A in virulence of the virus is well established, our knowledge about the extent of variation in the NS gene pool of influenza A viruses i...

    Authors: Siamak Zohari, Péter Gyarmati, Anneli Ejdersund, Ulla Berglöf, Peter Thorén, Maria Ehrenberg, György Czifra, Sándor Belák, Jonas Waldenström, Björn Olsen and Mikael Berg

    Citation: Virology Journal 2008 5:147

    Content type: Research

    Published on:

  24. Occult or latent hepatitis B virus (HBV) infection is defined as infection with detectable HBV DNA and undetectable surface antigen (HBsAg) in patients' blood. The cause of an overt HBV infection becoming an o...

    Authors: Formijn J van Hemert, Hans L Zaaijer, Ben Berkhout and Vladimir V Lukashov

    Citation: Virology Journal 2008 5:146

    Content type: Research

    Published on:

  25. Low levels of uracil in DNA result from misincorporation of dUMP or cytosine deamination. Vaccinia virus (VACV), the prototype poxvirus, encodes two enzymes that can potentially reduce the amount of uracil in ...

    Authors: Frank S De Silva and Bernard Moss

    Citation: Virology Journal 2008 5:145

    Content type: Research

    Published on:

  26. Our studies were aimed at developing a vaccination strategy that could provide protection against highly pathogenic avian influenza virus (AIV), H7N3 or its variants outbreaks. A purified viral stock of highly...

    Authors: Mirza Imran Shahzad, Khalid Naeem, Muhammad Mukhtar and Azra Khanum

    Citation: Virology Journal 2008 5:144

    Content type: Research

    Published on:

  27. RNA recombination is one of the two major factors that create RNA genome variability. Assessing its incidence in plant RNA viruses helps understand the formation of new isolates and evaluate the effectiveness ...

    Authors: Alla G Gagarinova, Mohan Babu, Martina V Strömvik and Aiming Wang

    Citation: Virology Journal 2008 5:143

    Content type: Short report

    Published on:

  28. The high diversity of HIV variants driving the global AIDS epidemic has caused many to doubt whether an effective vaccine against the virus is possible. However, by identifying the selective forces that are dr...

    Authors: Gama P Bandawe, Darren P Martin, Florette Treurnicht, Koleka Mlisana, Salim S Abdool Karim and Carolyn Williamson

    Citation: Virology Journal 2008 5:141

    Content type: Research

    Published on:

  29. Toll-like receptors have a key role in innate immune response to microbial infection. The toll-like receptor (TLR) family consists of ten identified human TLRs, of which TLR2 and TLR9 have been shown to initia...

    Authors: Piritta Peri, Riikka K Mattila, Helena Kantola, Eeva Broberg, Heidi S Karttunen, Matti Waris, Tytti Vuorinen and Veijo Hukkanen

    Citation: Virology Journal 2008 5:140

    Content type: Research

    Published on:

  30. In this report we describe the genomic sequence of guinea pig cytomegalovirus (GPCMV) assembled from a tissue culture-derived bacterial artificial chromosome clone, plasmid clones of viral restriction fragment...

    Authors: Mark R Schleiss, Alistair McGregor, K Yeon Choi, Shailesh V Date, Xiaohong Cui and Michael A McVoy

    Citation: Virology Journal 2008 5:139

    Content type: Short report

    Published on:

  31. Nipah virus (NiV) is a recently emerged paramyxovirus capable of causing fatal disease in a broad range of mammalian hosts, including humans. Together with Hendra virus (HeV), they comprise the genus Henipavirus ...

    Authors: Jared R Patch, Ziying Han, Sarah E McCarthy, Lianying Yan, Lin-Fa Wang, Ronald N Harty and Christopher C Broder

    Citation: Virology Journal 2008 5:137

    Content type: Research

    Published on:

  32. The Anopheles gambiae heat shock cognate gene (hsc70B) encodes a constitutively expressed protein in the hsp70 family and it functions as a molecular chaperone for protein folding. However, the expression of hsc7...

    Authors: Seokyoung Kang, Cheolho Sim, Brian D Byrd, Frank H Collins and Young S Hong

    Citation: Virology Journal 2008 5:136

    Content type: Research

    Published on:

  33. Viruses of the genus Begomovirus (Geminiviridae) are emerging economically important plant viruses with a circular, single-stranded DNA genome. Previous studies have shown that geminiviruses and RNA viruses exhib...

    Authors: Cica Urbino, Gael Thébaud, Martine Granier, Stéphane Blanc and Michel Peterschmitt

    Citation: Virology Journal 2008 5:135

    Content type: Methodology

    Published on:

  34. As part of efforts to control Japanese encephalitis (JE), the World Health Organization is producing a set of standards for JE surveillance, which require the identification of patients with acute encephalitis...

    Authors: Fidan Jmor, Hedley CA Emsley, Marc Fischer, Tom Solomon and Penny Lewthwaite

    Citation: Virology Journal 2008 5:134

    Content type: Review

    Published on:

  35. Neuraminidase inhibitors (NI) play a major role in plans to mitigate future influenza pandemics. Modeling studies suggested that a pandemic may be contained at the source by early treatment and prophylaxis wit...

    Authors: Stefan O Brockmann, Markus Schwehm, Hans-Peter Duerr, Mark Witschi, Daniel Koch, Beatriz Vidondo and Martin Eichner

    Citation: Virology Journal 2008 5:133

    Content type: Short report

    Published on:

  36. The transcription/replication of the influenza viruses implicate the terminal nucleotide sequences of viral RNA, which comprise sequences at the extremities conserved among the genomic segments as well as vari...

    Authors: Bernadette Crescenzo-Chaigne, Cyril Barbezange and Sylvie van der Werf

    Citation: Virology Journal 2008 5:132

    Content type: Research

    Published on:

  37. Identification of neutralizing antibodies with specificity away from the traditional mutation prone antigenic regions, against the conserved regions of hemagglutinin from H5N1 influenza virus has the potential...

    Authors: Angeline PC Lim, Conrad EZ Chan, Steven KK Wong, Annie HY Chan, Eng Eong Ooi and Brendon J Hanson

    Citation: Virology Journal 2008 5:130

    Content type: Research

    Published on:

  38. Chicken anemia virus (CAV) is the causative agent of chicken infectious anemia (CIA). Study on the type of CAV isolates present and their genetic diversity, transmission to their progeny and level of protectio...

    Authors: Zerihun Hailemariam, Abdul Rahman Omar, Mohd Hair-Bejo and Tan Ching Giap

    Citation: Virology Journal 2008 5:128

    Content type: Research

    Published on:

  39. Cell-surface viral proteins most frequently enter the cell through clathrin or caveolae endocytosis. Respiratory syncytial virus antigen internalization by immune cells is via caveolin, however, uptake of para...

    Authors: Abel Gutiérrez-Ortega, Carla Sánchez-Hernández and Beatriz Gómez-García

    Citation: Virology Journal 2008 5:127

    Content type: Short report

    Published on: