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Fig. 2 | Virology Journal

Fig. 2

From: Highly efficacious and safe neutralizing DNA aptamer of SARS-CoV-2 as an emerging therapy for COVID-19 disease

Fig. 2

Aptamer therapy does not induce inflammatory response in hACE2 transgenic mice lungs. A Schematic experimental design of mice treatment conditions for evaluation of mouse inflammatory cytokines by flow cytometry. B Assessment of cytokines/chemokines from lung cells cultured in the absence or presence of phorbol 12-myristate 13-acetate /ionomycin was done using the LEGENDplex Mouse Inflammation Panel kit and quantitated using flow cytometry. Data were analyzed with BioLegend’s LEGENDplex™ software. Individual dots represent data generated with cells from different mice. The p values were determined with one-way ANOVA, Dunnett’s multiple comparisons test. ns: denotes as nonsignificant

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Virology Journal

ISSN: 1743-422X