Fig. 3From: RIG-I is responsible for activation of type I interferon pathway in Seneca Valley virus-infected porcine cells to suppress viral replicationKnockout of RIG-I enhanced SVV replication in PK-15 cells. a RIG-I KO and WT PK-15 cells were infected with SVV (MOI of 0.1) respectively, and the cellular samples were collected at 10Â hpi. Viral RNA levels were detected by qPCR, (b) viral protein levels were detected by western bloting, and (c) viral protein levels were detected by IFA. d RIG-I KO and WT PK-15 cells were infected with equal amounts of SVV for 6, 10 or 14Â h, the viral titers were detected by TCID50 assayBack to article page