Figure 2
From: Oncolytic parvoviruses: from basic virology to clinical applications
The oncolytic rat parvovirus H-1PV. A) A model of the icosahedral capsid is illustrated showing the 2, 3 and 5 fold axes of symmetry [28] B) The 5Â kb single-stranded linear DNA genome has unique palindromic terminal sequences (Pal) that serve as self-priming origins of replication. Transcription is regulated by the P4 and P38 promoters, whose position is indicated by arrows. There are two transcription units coding for the non-structural (NS) and structural (VP) proteins, respectively.