Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific

Table 1 Sequence comparisons of clinical isolates NH1067, NH1125

Genomic segment^a	Length in bases^b	Nucleotide differences	Non-sense^c	Mis-sense^c	Silent^c
3’end-NS1	98	1
NS1 gene	420	1			1
NS1-NS2	107	0
NS2 gene	375	4		1	3
NS2-N	136 (137)	6
N gene	1176	16		1	15
N-P	32	0
P gene	726	5		1	4
P-M	186 (188)	11
M gene	771	10			10
M-SH	268	10
SH gene	198	4			4
SH-G	189	4
G gene	888 (951)	23		13	10
G-F	88	0
F gene	1725	20		4	16
F-M2-1	225 (226)	8
M2-1 gene	588	4		2	2
M2-1-M2-2^d	35	0
M2-2 gene	273	4			4
M2-2-L	65	2
L gene	6501	59		8	51
L-5’end	216	2
Total	15216 (15283)	194	0	30	120

^aGene coding sequences (“gene”) or intergenic (inter-ORF) segment listed unless otherwise noted (3’ and 5’ end).
^bNH1067 length in () when it differs from NH1125. NH1067 G gene contains a 3 base and 60 base insertion.
^cNon-sense, mis-sense and silent nucleotide differences between the 2 strains are listed for coding sequences only.
^dM2-1 and M2-2 overlap by 35 nucleotides.

ISSN: 1743-422X