Alignment of ZANK amino acid sequence with vertebrate and invertebrate anykrins. ZANK amino acids present in the solved ZEBRA structure are shown aligned with corresponding regions of non-viral ankyrins. Alignments were performed using clustalx, and individual vertebrate ankyrin stem loop domains from IκB, p53BP2/ASPP2, BCL3, and invertebrate ankyrins Unc-22 and Cactus. Approximate borders of stems (s) and loops (l) derived from PyMOL generated structures are shown at the top of the figure. Colored regions indicate highly conserved or identical amino acids according to the color scheme described at http://ekhidna.biocenter.helsinki.fi/pfam2/clustal_colours.