Structure of ZEBRA protein. The carboxyl terminus of dimeric ZEBRA protein bound to a ZRE oligonucleotide (orange) is shown. This image was generated from previously determined ZEBRA molecular coordinates using PyMOL. The ZANK (ZEBRA ANKyrin-like region) carboxyl terminus of ZEBRA is highlighted in blue. ZANK is composed of two regions, a highly structured alpha helix stem highlighted in darker blue (the ZANK stem region) and a partially solved unstructured region continuing to the end of the protein highlighted in light blue (the ZANK loop region).