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Table 2 Transmissibility of H7N9 influenza virus in mice put in contact with infected mice

From: Transmission of H7N9 influenza virus in mice by different infective routes

Virus

Virus titer (mean log10TCID50 ± SD)

 

Lung

Kidney

Intestine

Brain

Nose

Infected contact miceb

Weight loss (%)c

Seroconvertedd

Days post-infection

5

7

5 and 7

5

7

5

5

   

A/SZ/406H/06 A/CA/07/09

-

 

NPa

-f

-

-

NP

0

0

0

2.07 ± 0.16

1.47 ± 0.19

NP

-

-

-

+

8/14

11

4/7

A/Anhui/1/2013

1.26 ± 0.41

0.67 ± 0.01

-

1.34 ± 0.25

0.97 ± 0.01

+e

+

7/14

6

3/7

  1. aNP, Not performed.
  2. bNumber of contact mice containing virus in the lung, brain, and nose at 5 and 7 days after co-housing.
  3. cMaximum proportional weight loss.
  4. dHI titers >40.
  5. eCyotpathic effects were observed but TCID50 values were less than 0.5.
  6. fViable virus was not detected after three passages in MDCK cells.