Skip to main content
Figure 3 | Virology Journal

Figure 3

From: Decreased antigenicity profiles of immune-escaped and drug-resistant hepatitis B surface antigen (HBsAg) double mutants

Figure 3

The supernatants from each plasmid transfection were analyzed for HBsAg using five ELISA kits. (A) Zhu Hai LivZon Diagnostic INC (LZ); (B) Beijing WanTai Biological Pharmacy Enterprise Limited Company (WT); (C) Beijing Big-GBI Biotech Limited Company (GBI); (D) Beijing BioNeovan Limited Company (BN); and (E) Shenzhen Kang Sheng Bao Bio-Technology Limited Company (KSB). With the rtM204I (sI195M) mutation in the backbone of sG145K, avidity was reduced significantly in four kits. The exception was with ELISA kit GBI. rtM204V (sW196S) mutation did not cause antigenic variation of sG145K HBsAg. *, p < 0.05, compared with sG145K HBsAg.

Back to article page

Virology Journal

ISSN: 1743-422X