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Fig. 2 | Virology Journal

Fig. 2

From: Presepsin as a prognostic biomarker in COVID-19 patients: combining clinical scoring systems and laboratory inflammatory markers for outcome prediction

Fig. 2

The predictive value of Presepsin for the severity of illness and 28-day mortality in COVID-19 patients. (A) Comparison of Presepsin levels among different severity groups of COVID-19 patients. (B) Comparison of Presepsin levels between the non-mechanical ventilation and mechanical ventilation groups. (C) Comparison of Presepsin levels between the 28-day survival and death groups. Data are displayed as a median with interquartile range (IQR) and were compared using the Mann-Whitney U test. Multiple samples were compared using the non-parametric Kruskal-Wallis test. (D) Receiver Operating Characteristic (ROC) curve of Presepsin for predicting the need for mechanical ventilation in COVID-19 patients, with an area under the ROC curve (AUC) of 0.866 (95% confidence interval [CI]: 0.800-0.932). (E) ROC curve of Presepsin for predicting 28-day mortality in COVID-19 patients, with an AUC of 0.828 (95% confidence interval [CI]: 0.737–0.920). (F) Kaplan-Meier curve for patients divided into two groups based on the median Presepsin level: above-median group and below-median group, for 28-day survival. A p-value < 0.05 was considered significant

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Virology Journal

ISSN: 1743-422X