Fig. 7
From: Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection
Vpr induces loss of histone DNA methylation. (A, B) The effect of Vpr on histone DNA methylation. Number of differentially methylated cytosines (DMCs) (A) or differentially methylated regions (DMRs). (C) Example of genome browser tracks of histone DNA methylation profiles in HIV-1-△Vpr and HIV-1-Vpr infection. (D) The effect of Vpr on the transcription of histone genes through real-time quantitative RCR. Data are presented as means ± SD for three technical replicates. P values were calculated using an unpaired t-test.