Fig. 1
From: Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection
Landscape of Vpr-induced DNA methylation. (A) The schematic depicts the experimental design employed in the Whole Genome Bisulfite Sequencing (WGBS) study. (B) Flow cytometry plots are presented as representatives, illustrating the HIV-1 infection of primary CD4 + T cells in the context of WGBS. (C–E) The methylation levels across the genome are displayed for CG (C), CHG (D), and CHH (E) contexts. (F) A violin plot is utilized to showcase the overall distribution of methylation levels, with a bin size of 10 kb. (G, H) The mean DNA methylation levels are computed based on elemental (G) and CGI (H) patterns.