Table 2 Notable mutation sites in cs2301
From: Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China
Gene | Reference | Mutation | Structural interaction(s) | Multiple position effect | Prev. reported effect |
|---|---|---|---|---|---|
HA | A/Duck/HongKong/24/1976(H4N2) | V98I, S342A | â‘£ | - | - |
I106V | ④⑤ | - | - | ||
T140S | ④⑤⑥ | ①| - | ||
E173A | ④⑤⑥ | ①②③ | ①②③ | ||
T105A, I182V | ④⑤⑥ | - | - | ||
PB2 | K340R, L464M | â‘£ | - | - | |
I292V | - | - | â‘ | ||
NA | A/Duck/Taiwan/0526/1972(H6N1) | I75L, I188T, G189S, F445L | â‘£ | - | - |
D309N | ④⑤ | - | - | ||
N222D | ④⑤⑥ | ②③ | ②③ | ||
S248N | ④⑤⑥⑦ | ⑧ | - | ||
S449N | ④⑤⑩ | - | - | ||
I2N, T48P, T94I, I234V, D273N, V288I, I289M, R352K, K355N | ⑤ | - | - | ||
P51Q | ⑨ | - | - | ||
MP | K101R, P121T, Q72R | â‘£ | - | - |