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Fig. 12 | Virology Journal

Fig. 12

From: Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza

Fig. 12

Pathomorphological evaluation of lung tissues of hamsters immunized with FluCoVac-19, or control LAIV, as well as non-immunized animals (PBS group) on day 5 after challenge with SARS-CoV-2. A Representative macrographs of the lungs of hamster from each study group. B Representative micrographs of the hematoxylin-eosin stained lung sections (magnification ×50): asterisk – foci and/or diffuse mix cell infiltrate C Representative micrographs of the hematoxylin-eosin stained lung sections (magnification ×20): AS – alveolar sept, EH – epithelial hyperplasia, ET – endothelial cells, ER – erythrocytes, IN – infiltration cells, MP – macrophages. D Semi-quantitative analyses of the airway, lung/alveolar and vascular damage. Data were analyzed by one-way ANOVA with Tukey’s post-hoc multiple analyses test. *—p < 0.05

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Virology Journal

ISSN: 1743-422X