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Table 2 General clinical characteristics of the patients

From: Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B

Variables

IT(n=46)

IA(n=50)

LR(n=20)

RA(n=21)

HC(n=32)

P value

Male, n (%)

22(47.83)

37(74.00)

9(45.00)

13(61.90)

18(56.25)

0.067 c

Age (years)

35(31-46)

39(34-49)

40(31-55)

44(36-49)

48(32-58)

0.053 b

HbsAg(IU/ml)

33725.95(6390.21-54364.65)

10819.65(4075.77-21753.43)

3679.90(1095.77-7375.08)

3050.29(1684.47-8662.55)

NA

<0.001 b

HBeAg(IU/ml)

1394.59(541.24-1588.91)

880.70(262.23-1436.98)

NA

NA

NA

<0.001 a

log10[HBV-DNA]

7.97(5.25-8.40)

6.92(5.49-8.06)

3.45(3.08-3.96)

4.79(3.47-5.81)

NA

<0.001 b

ALT(U/L)

27.50(17.75-35.00)

103.00(66.25-225.50)

20.00(15.00-27.75)

74.00(25.50-154.50)

15.50(11.50-23.50)

<0.001 b

AST(U/L)

21.50(18.00-27.25)

65.00(44.75-114.25)

20.00(18.00-24.75)

41.00(22.50-99.50)

19.00(15.50-22.00)

<0.001 b

AKP(U/L)

77.00(61.75-94.25)

90.50(76.00-104.50)

75.50(62.75-97.50)

88.00(66.50-98.00)

74.50(57.50-84.00)

0.029 b

GGT(U/L)

19.00(12.00-31.00)

38.50(27.25-94.50)

16.50(12.25-25.25)

30.00(19.50-61.50)

21.00(13.25-27.75)

<0.001 b

TBIL(µmol/L)

9.45(7.50-14.10)

13.70(9.30-16.98)

10.45(8.03-14.33)

12.30(9.15-18.10)

9.70(8.15-14.33)

0.007 b

ALB(g/L)

46.25(44.20-48.83)

45.60(43.15-48.83)

47.80(46.10-49.93)

48.20(45.45-50.30)

47.15(46.05-49.03)

0.064 b

Cr(µmol/L)

72.00(54.00-79.00)

69.00(60.00-76.50)

65.00(57.00-78.00)

71.50(56.25-78.75)

69.50(64.25-79.00)

0.903 b

PLT(10^9/L)

218.00(182.75-252.00)

192.50(154.25-232.25)

220.00(183.75-235.00)

185.00(151.50-224.00)

228.50(200.25-272.75)

0.005 b

PTA(%)

119.00(109.00-122.75)

103.50(88.50-107.75)

115.00(110.50-122.00)

102.00(92.00-109.00)

110.00(103.00-119.00)

0.007 b

INR

0.90(0.89-0.95)

0.98(0.96-1.08)

0.92(0.89-0.94)

0.99(0.95-1.06)

0.94(0.90-0.98)

<0.001 b

AFP(ng/ml)

2.41(1.81-3.60)

5.68(2.83-15.89)

2.06(1.48-3.16)

2.82(1.92-4.50)

2.90(2.46-4.75)

<0.001 b

  1. Quantitative variables were expressed as medians (25th, 75th percentage)
  2. Qualitative variables were expressed as number (percentage)
  3. a Mann–Whitney U test. b Kruskal–Wallis H test. c chi-square test