Table 3 MHC-II epitopes prediction from HA and NA proteins
From: A computational approach to design a multiepitope vaccine against H5N1 virus
Pos | Allele | Peptide | Affinity (nM) | Antigenicity |
|---|---|---|---|---|
HA protein | ||||
462–477 | DRB1_0103 | NLYDKVRLQLRDNAK | 2778.9 | 1.1390 |
443–457 | DRB1_0301 | ELLVLMENERTLDFH | 87.4 | 1.0452 |
210–224 | DRB1_0401 | PTTYISIGTSTLNQR | 19.7 | 1.0883 |
442–456 | DRB1_0405 | AELLVLMENERTLDF | 20.4 | 1.0504 |
464–476 | DRB4_0101 | LYDKVRLQLRDNAKE | 25.6 | 1.0144 |
210–224 | HLA-DQA10501-DQB10301 | PTTYISIGTSTLNQR | 29.9 | 1.0883 |
NA protein | ||||
9–23 | DRB1_0403 | TIGSICMVIGMVSLM | 0.1 | 1.4483 |
13–27 | HLA-DQA10102-DQB10501 | ICMVIGMVSLMLQIG | 0.2 | 1.5671 |
10–24 | HLA-DQA10103-DQB10603 | GSICMVIGMVSLMLQ | 0.5 | 1.2727 |