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Fig. 1 | Virology Journal

Fig. 1

From: Cross-neutralizing antibody against emerging Omicron subvariants of SARS-CoV-2 in infection-naïve individuals with homologous BNT162b2 or BNT162b2(WT + BA.4/5) bivalent booster vaccination

Fig. 1

PRNT50 antibody titres to wild-type (WT) SARS-CoV-2 and Omicron subvariants pango lineage BA.5, XBB.1.5, XBB.1.16, XBB.1.9.1, XBB.2.3.2, EG.5.1, HK.3, BA.2.86 and JN.1. Infection-naïve individuals with three doses BNT162b2 boosted by a monovalent WT BNT162b2 (BBBB) vaccine (N = 18) are labelled by blue dots, and those boosted with a BNT162b2 bivalent vaccine (BBB + BIV) (N = 8) are labelled by red triangles. The Geometric mean titre (GMT) and 95% confidence intervals of GMT are denoted. Mann-Whitney U test was used to test significant differences between the GMTs of the groups. The horizontal dotted line at a titre 1:25.6 represents the 50% protective threshold against symptomatic infection (see text) as defined by Khoury et al. [8,9,10] and the shaded area represents the 95% confidence interval of this protective threshold

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Virology Journal

ISSN: 1743-422X