Table 6 Association of studied SNPs with COVID-19 severity

rs2285666

females

Genotypes

CC

42

64.6%

57

53.8%

-

1

Reference

CT

13

20.0%

25

23.6%

0.379

1.241

0.768–2.005

TT

10

15.4%

24

22.6%

0.178

1.420

0.853–2.362

Dominant

CC

42

64.6%

57

53.8%

-

1

Reference

CT + TT

23

35.4%

49

46.2%

0.163

1.321

0.894–1.952

Recessive

CC + CT

55

84.6%

82

77.4%

-

1

Reference

TT

10

15.4%

24

22.6%

0.246

1.339

0.818–2.191

Alleles

C

97

74.6%

139

65.6%

-

1

Reference

T

33

25.4%

73

34.4%

0.078

1.306

0.971–1.758

rs2285666

males

Alleles

C

19

20.9%

89

39.4%

-

1

Reference

T

7

7.7%

31

13.7%

0.909

1.032

0.602–1.771

rs12329760

Genotypes

CC

59

64.8%

172

76.1%

-

1

Reference

CT

19

20.9%

30

13.3%

0.066

0.689

0.463–1.025

TT

13

14.3%

24

10.6%

0.230

0.759

0.484–1.190

Dominant

CC

59

64.8%

172

76.1%

-

1

Reference

CT + TT

32

35.2%

54

23.9%

0.044

0.718

0.520–0.991

Recessive

CC + CT

78

85.7%

202

89.4%

-

1

Reference

TT

13

14.3%

24

10.6%

0.364

0.814

0.523–1.268

Alleles

C

137

75.3%

374

82.7%

-

1

Reference

T

45

24.7%

78

17.3%

0.034

0.759

0.588–0.979