Table 3 Meta-analysis of odds ratios for signs, symptoms, and conditions in non-hospitalized children with COVID-19 compared to negative controls, with comorbidity-matched subgroup analysis
Sign/Symptom/Condition | Overall | Matched comorbidity | ||||
|---|---|---|---|---|---|---|
Studies No | Pooled odds ratio (95% CI) | I2% | Studies No | Pooled odds ratio (95% CI) | I2% | |
Abdominal pain | 4 | 0.99 (0.74–1.33) | 93.1 | – | – | – |
Sore throat | 5 | 1.22 (1.01–1.48) | 67.6 | 3 | 1.30 (0.84–2.02) | 72.5 |
Fatigue | 4 | 1.84 (1.56–2.16) | 66 | – | – | – |
Headache | 6 | 1.24 (0.89–1.73) | 94.5 | 3 | 0.88 (0.78–0.98) | 0 |
Fever | 3 | 0.96 (0.76–1.21) | 0 | – | – | – |
Dizziness | 5 | 1.41 (1.08–1.85) | 81.5 | 3 | 0.97 (0.76–1.22) | 0.46 |
Anosmia | 3 | 10.45 (7.46–14.62) | 0 | – | – | – |
Congested or runny nose | 4 | 0.68 (0.40–1.16) | 0 | 3 | 0.65 (0.36–1.17) | 0 |
Cough | 6 | 0.97 (0.88–1.08) | 0 | 3 | 0.91 (0.83–1.00) | 0 |
Dyspnea | 5 | 1.56 (0.97–2.51) | 96.7 | 3 | 0.90 (0.75–1.08) | 8.7 |
Anxiety | 3 | 0.80 (0.64–1.01) | 0 | – | – | – |
Brain fog | 5 | 1.63 (1.24–2.15) | 51 | 3 | 1.10 (0.54–2.23) | 0.1 |
Chest pain | 4 | 1.25 (0.70–2.21) | 92.8 | 3 | 0.88 (0.76–1.03) | 0 |
Myalgia/arthralgia | 7 | 1.21 (0.75–1.95) | 92.6 | 5 | 0.83 (0.61–1.12) | 13.9 |