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Fig. 8 | Virology Journal

Fig. 8

From: A novel film spray containing curcumin inhibits SARS-CoV-2 and influenza virus infection and enhances mucosal immunity

Fig. 8

Various actions of the curcumin film spray. Formulation of curcumin film spray shows various actions on prevention of COVID-19; First, it can inhibit SARS-CoV-2 infection by inhibiting ACE-2 binding. Second, the film spray upregulates the production of antimicrobial peptides LL-37 and HD-5 produced by oral epithelial cells, which have been previously reported to inhibit SARS-CoV-2 infection in silico. Third, the film spray induced the production of antiinflammatory cytokines IL-6 and TNF-α produced by oral epithelial cells. In addition, the film spray inhibits influenza virus infection.The infographic was designed by BioRender.com (https://app.biorender.com)

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