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Table 3 Mutations lost in sample 9

From: Chronic COVID-19 infection in an immunosuppressed patient shows changes in lineage over time: a case report

Position

Mutation

Lineage characteristic of

Sample 1 (%)

Sample 2 (%)

Sample 3 (%)

Sample 4 (%)

Sample 5 (%)

Sample 6 (%)

Sample 7 (%)

Sample 8 (%)

Sample 9 (%)

Annotation

Gene

315

Δ3 bp

Neither

100

100

100

100

100

100

100

100

14.10

coding (50–52/13203 nt)

orf1ab → 

1,321

A → C

B.1.1.176

58.60

92.70

86.30

91.70

77.50

23.20

100

100

23.00

E352D (GAA → GAC)

orf1ab → 

2,189

C → T

Neither

100

100

100

100

100

100

100

100

 

L642F (CTT → TTT)

orf1ab → 

6,114

C → T

Both

100

100

100

100

100

100

100

100

27.50

P1950L (CCT → CTT)

orf1ab → 

6,352

G → T

Neither

100

100

100

100

100

100

100

100

36.10

K2029N (AAG → AAT)

orf1ab → 

8,208

C → T

Neither

100

100

100

100

100

100

100

100

37.20

T2648I (ACT → ATT)

orf1ab → 

14,767

G → T

B.1.1.176

100

100

100

100

100

100

100

100

30.30

A4835S (GCT → TCT)

orf1ab → 

21,621

C → T

B.1.1.176

100

100

100

100

100

100

100

100

37.60

T20I (ACC → ATC) ‡

S → 

22,632

G → A

B.1.1.176

100

100

100

100

100

100

100

100

33.30

R357K (AGA → AAA)

S → 

25,386

C → T

Neither

100

100

100

100

100

100

100

100

30.70

intergenic (+ 2/-7)

S → / → ORF3a

25,947

G → T

B.1.1.176

100

100

100

100

100

100

100

100

16.60

Q185H (CAG → CAT)

ORF3a → 

28,361

G → A

B.1.1.176

100

100

100

100

100

100

100

100

33.40

G30R (GGA → AGA)

N → 

28,905

C → T

B.1.1.176

100

100

100

100

100

100

100

100

29.40

A211V (GCT → GTT)

N → 

  1. Percentages reflet the proportion of sequencing reads with the listed mutation. "Neither" indicates that the mutation is not characteristic of B.1.1.176 or BA.1. "Both" indicates that the mutation is characteristic of both B.1.1.176 and BA.1, while a blank cell indicates that the listed mutation was present in 0% of reads